The Best Hotels Closest to Museum of Life and Science in Raleigh for 2026

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

elizabeth

₩190,513 total

includes taxes & fees

Aug 23 - Aug 24

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board

2. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

LILIANA

₩149,484 total

includes taxes & fees

Sep 1 - Sep 2

3. Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Derrick

₩98,243 total

includes taxes & fees

Sep 6 - Sep 7

4. Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Dorcas

₩197,129 total

includes taxes & fees

Aug 16 - Aug 17

5. The Colonial Inn, an Ascend Collection Hotel

18.9 km from Museum of Life and Science

Sharon

₩183,994 total

includes taxes & fees

Aug 23 - Aug 24

6. Rizzo Center, a Destination by Hyatt Hotel

16.3 km from Museum of Life and Science

James

₩287,191 total

includes taxes & fees

Aug 16 - Aug 17

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

17.5 km from Museum of Life and Science

Ryan

₩190,094 total

includes taxes & fees

Aug 16 - Aug 17

8. Fairfield by Marriott Inn & Suites Durham

17.3 km from Museum of Life and Science

Jeaneth

₩166,183 total

includes taxes & fees

Aug 27 - Aug 28

9. Hyatt Place Durham Southpoint

15.3 km from Museum of Life and Science

Kelly

₩204,904 total

includes taxes & fees

Aug 16 - Aug 17

10. Hyatt House Raleigh / RDU / Brier Creek

17.1 km from Museum of Life and Science

Darius

₩217,334 total

includes taxes & fees

Aug 16 - Aug 17

11. The Westin Raleigh-Durham Airport

17.5 km from Museum of Life and Science

donald

₩352,561 total

includes taxes & fees

Aug 28 - Aug 29

12. DoubleTree Suites by Hilton Raleigh - Durham

13.3 km from Museum of Life and Science

Zachary

₩140,238 total

includes taxes & fees

Aug 23 - Aug 24

13. Tru by Hilton Raleigh Durham Airport

19.7 km from Museum of Life and Science

George

₩170,291 total

includes taxes & fees

Aug 30 - Aug 31

Daily cooked-to-order breakfast for a fee

14. Courtyard Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Pia

₩190,200 total

includes taxes & fees

Aug 7 - Aug 8

15. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

17.5 km from Museum of Life and Science

Johnathan

₩256,097 total

includes taxes & fees

Aug 23 - Aug 24

16. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

19.7 km from Museum of Life and Science

Zubair

₩162,597 total

includes taxes & fees

Aug 21 - Aug 22

17. The Carolina Inn, a Destination by Hyatt Hotel

19.3 km from Museum of Life and Science

Tricia

₩485,642 total

includes taxes & fees

Aug 17 - Aug 18

18. Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

KEVIN

₩236,820 total

includes taxes & fees

Aug 16 - Aug 17

19. Residence Inn Raleigh-Durham Airport/Brier Creek

15.9 km from Museum of Life and Science

Claudia

₩217,572 total

includes taxes & fees

Aug 21 - Aug 22

20. JB Duke Hotel

5.6 km from Museum of Life and Science

Manit

₩240,407 total

includes taxes & fees

Aug 30 - Aug 31

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Compare popular hotels close to Museum of Life and Science

Property	Property class	Guest rating
Hampton Inn & Suites Durham/North I-85	2.5 star property	9.0 Wonderful 1,005 reviews	View
Comfort Inn & Suites Durham near Duke University	2.5 star property	8.6 Excellent 1,097 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	2.0 star property	6.8 1,001 reviews	View
Hampton Inn & Suites Durham University Medical Center	2.5 star property	9.6 Exceptional 533 reviews	View
The Colonial Inn, an Ascend Collection Hotel	4.0 star property	9.6 Exceptional 305 reviews	View

Top Museum of Life and Science Hotel Reviews

University Inn Durham next to Duke University Medical Center

10/10 Excellent

"Would absolutely stay here again! We were a family of five visiting the area to tour colleges. We stayed here for 3 nights in order to spend time on the Duke University and UNC campuses. It was the perfect location for visiting everywhere we needed to be. We did not visit the hospital however it was right across the street which was so convenient for anyone staying for treatments, etc. The room is spacious enough for everyone. We had a suite which was great having the sofa and additional space. The staff was so friendly and very helpful with directions and recommendations. Our only complaint, which is minor, is the size of the bathroom. We were fine however be prepared that the area for the toilet and shower is very tight."

21c Museum Hotel Durham

8/10 Good

"The gentleman handing valet wer the nicest. When I went to check in I went up to the second floor. I think you're supposed to and it doesn't give you very clear directions on where check-in is at. So when I turn the corner I ask the gentleman that was sitting behind the wall. Hey can you tell me we're checking is and he was like here with such an attitude. He spoke so quickly through the spiel that I had no idea what he had even said. The room was comfortable. It was very clean besides the mirror. You could tell that somebody had sprayed the mirror but didn't wipe it off and there was a minor break in the mirror(for the nightly price I expect the mirror not to be broken or dirty which is why I'm giving it four stars) The bed was extremely comfortable. So were the pillows. The artwork in the hotel is nice. There's a lot of stuff within walking distance. Most definitely have to Loaf for breakfast needs because they have the best chocolate stuffed croissants.(2 minute walk from the hotel) I would recommend and stay here again."

Red Roof Inn Durham - Duke Univ Medical Center

8/10 Good

"The hotel is older but it’s well kept. For the price I would absolutely stay there again without hesitation. There are also plenty of outlets for phones and such. Two things I disliked - no elevator and no mini fridge in the room. However, there is free ice on the first floor."

Residence Inn Durham McPherson/Duke University Medical Cntr

10/10 Excellent

"This is always a great MARRIOTT chain, and they did amazingly well considering that a major access road to the hotel is now under construction. It was difficult to gain access, but once the detour signs were located, it was fine."

Other attractions near Museum of Life and Science

Brightleaf Square

9.6/10 (8 reviews)

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 11 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Comfort Inn & Suites Durham near Duke University.

How many hotels will I find close to Museum of Life and Science?

Expedia has 11 hotels and other accommodations within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.

Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?

To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Museum of Life and Science, Raleigh from ₩98,243

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Our top choices for Museum of Life and Science hotels

1. Hampton Inn & Suites Durham/North I-85

2. Comfort Inn & Suites Durham near Duke University

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Hampton Inn & Suites Durham University Medical Center

5. The Colonial Inn, an Ascend Collection Hotel

6. Rizzo Center, a Destination by Hyatt Hotel

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

8. Fairfield by Marriott Inn & Suites Durham

9. Hyatt Place Durham Southpoint

10. Hyatt House Raleigh / RDU / Brier Creek

11. The Westin Raleigh-Durham Airport

12. DoubleTree Suites by Hilton Raleigh - Durham

13. Tru by Hilton Raleigh Durham Airport

14. Courtyard Raleigh-Durham Airport/Brier Creek

15. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

16. Towneplace Suites By Marriott Raleigh-Durham Airport/Morrisville

17. The Carolina Inn, a Destination by Hyatt Hotel

18. Hilton Garden Inn Durham/University Medical Center

19. Residence Inn Raleigh-Durham Airport/Brier Creek

20. JB Duke Hotel

Compare popular hotels close to Museum of Life and Science

Top Museum of Life and Science Hotel Reviews

University Inn Durham next to Duke University Medical Center

Other attractions near Museum of Life and Science

Brightleaf Square

Frequently asked questions