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Our top choices for Palestine Regional Medical Center hotels

Exterior
Comfort Suites Palestine

Comfort Suites Palestine

Comfort Suites Palestine
2.5 star property
0.8 km from Palestine Regional Medical Center
9.2 out of 10, Wonderful, (885)
"Clean room and courteous staff "
United States
Carlos
The price is ₩163,456
₩187,974 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Comfort Suites Palestine
Reception
Hampton Inn & Suites Palestine

Hampton Inn & Suites Palestine

Hampton Inn & Suites Palestine
2.5 star property
0.8 km from Palestine Regional Medical Center
9.0 out of 10, Wonderful, (630)
"Hotel was fine but the staff was awful. There was b"
United States
Josh
The price is ₩152,404
₩175,264 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Hampton Inn & Suites Palestine
Lobby
La Quinta Inn & Suites by Wyndham Palestine

La Quinta Inn & Suites by Wyndham Palestine

La Quinta Inn & Suites by Wyndham Palestine
3.0 star property
0.2 km from Palestine Regional Medical Center
8.8 out of 10, Excellent, (867)
"Its a good place to stay with family. No complaints "
United States
Srikanth
The price is ₩171,562
₩197,297 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Quinta Inn & Suites by Wyndham Palestine
Reception
Premier Inn Palestine

Premier Inn Palestine

Premier Inn Palestine
2.5 star property
3 km from Palestine Regional Medical Center
6.8 out of 10, (317)
"It was very clean and my room was well accommodated with a fridge, microwave, And a huge bed."
United States
Nathaniel
The price is ₩93,630
₩107,674 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Premier Inn Palestine
BBQ/picnic area
Best Western Palestine Inn

Best Western Palestine Inn

Best Western Palestine Inn
2.5 star property
3.2 km from Palestine Regional Medical Center
7.8 out of 10, Good, (525)
"Yes"
United States
Leigh
The price is ₩103,223
₩118,707 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Best Western Palestine Inn
BBQ/picnic area
Super 8 by Wyndham Palestine

Super 8 by Wyndham Palestine

Super 8 by Wyndham Palestine
2.0 star property
4.3 km from Palestine Regional Medical Center
7.8 out of 10, Good, (419)
"Rooms were clean and staff was very nice. "
United States
Donna
The price is ₩104,224
₩119,857 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Palestine
Exterior
Holiday Inn Express Palestine by IHG

Holiday Inn Express Palestine by IHG

Holiday Inn Express Palestine by IHG
2.5 star property
4.7 km from Palestine Regional Medical Center
8.8 out of 10, Excellent, (593)
"Clean room, staff was friendly and helpful "
United States
Jackie
The price is ₩170,132
₩195,652 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express Palestine by IHG
Fridge, microwave, eco-friendly cleaning products
Motel 6 Palestine, TX

Motel 6 Palestine, TX

Motel 6 Palestine, TX
2.0 star property
4.9 km from Palestine Regional Medical Center
7.8 out of 10, Good, (293)
"The room was extremely clean, appeared to be recently updated. Very nice. Courteous staff."
United States
Karen
The price is ₩107,226
₩123,311 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Motel 6 Palestine, TX
Outdoor pool
Express Inn & Suites

Express Inn & Suites

Express Inn & Suites
2.5 star property
4.7 km from Palestine Regional Medical Center
7.4 out of 10, Good, (524)
"Excellent location, great staff, clean property and close proximity to local attractions."
United States
Roger
The price is ₩93,244
₩107,231 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Express Inn & Suites
Standard Room, 2 Queen Beds, Non Smoking | Free WiFi
Rodeway Inn Palestine

Rodeway Inn Palestine

Rodeway Inn Palestine
2.5 star property
4.6 km from Palestine Regional Medical Center
7.2 out of 10, Good, (43)
"No hot water at all, bathroom sink wouldnt drain. Stains on thr top sheet and black hair on the pillow case. "
United States
Michael
The price is ₩88,268
₩101,508 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Rodeway Inn Palestine
Lobby
Budget Inn By OYO Palestine Tx Hwy 79

Budget Inn By OYO Palestine Tx Hwy 79

Budget Inn By OYO Palestine Tx Hwy 79
2.5 star property
5.4 km from Palestine Regional Medical Center
4.2 out of 10, (25)
"This place is an hourly motel for prostitutes. Don’t book here. Mold on the walls, doors won’t close. Absolutely disgusting. "
United States
Leeah
The price is ₩66,121
₩84,676 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Budget Inn By OYO Palestine Tx Hwy 79
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Palestine Regional Medical Center Hotel Reviews

Best Western Jacksonville Inn

Best Western Jacksonville Inn

10/10 Excellent
"Good visit. Friendly receptionist who checked us in. Kids loved the pool. Room cleaned. Breakfast variety not so good. "
nadia 1-night trip
Posted 4 days ago
Best Western Jacksonville Inn

Hotels near other Palestine Regional Medical Center attractions

Historic Anderson County Courthouse Located in Palestine, Texas

Anderson County Courthouse

4.1/5 (15 reviews)
Anderson County Courthouse is just one of the places to see in Palestine, so why not enjoy the other things to explore during your travels? Experience the entertainment venues and theater scene in this family-friendly area.
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Texas State Railroad Station - Depot - Palestine Station.

Texas State Railroad: Palestine Depot

4.6/5 (58 reviews)
You can take time to visit Texas State Railroad: Palestine Depot during your travels to Palestine. Experience the festivals and theater scene in this family-friendly area.
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Frequently asked questions

What's the area like around Palestine Regional Medical Center?
Palestine Regional Medical Center is located in Palestine. You'll find 22 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay close to Palestine Regional Medical Center?
Adjacent to Palestine Regional Medical Center, La Quinta Inn & Suites by Wyndham Palestine is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an outdoor pool. Other good options within a short distance include Comfort Suites Palestine and Hampton Inn & Suites Palestine.
How many hotels can I expect to find near Palestine Regional Medical Center?
Expedia has 22 hotels and other accommodations a few miles from Palestine Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Palestine Regional Medical Center, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If your reservation is non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to get top deals close to Palestine Regional Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Palestine Regional Medical Center?
To find more details about picking new dates or cancelling your stay near Palestine Regional Medical Center, go to https://www.expedia.com/service/.
What can I see and do near Palestine Regional Medical Center?
Sights like Redlands Hotel and Palestine Community Theatre highlight some of the local culture. You might spend a leisurely day outdoors at Davey Dogwood Park and Green Park. If you want to see more of the surrounding area, you might plan a visit to Texas State Railroad: Palestine Depot and University of Texas at Tyler Palestine Campus.