Find Resorts & Hotels with Spas in Panajachel

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Panajachel Resorts & Hotels with Spas

Our top choices for Panajachel hotels with a spa

Lake View Premium Room | Premium bedding, desk, blackout drapes, iron/ironing board
Porta Hotel del Lago

Porta Hotel del Lago

Porta Hotel del Lago
3.5 star property
Panajachel
8.8 out of 10, Excellent, (1004)
"The staff and breakfast is amazing! Great location "
United States
Maria del
Porta Hotel del Lago
Couples treatment rooms, deep-tissue massages, Swedish massages
Jenna's River Bed & Breakfast

Jenna's River Bed & Breakfast

Jenna's River Bed & Breakfast
3.0 star property
Panajachel
9.2 out of 10, Wonderful, (295)
"Great location, friendly staff and amazing views. Would most definitely stay again!"
United States
Dania
The price is ₩145,386
₩177,371 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Jenna's River Bed & Breakfast
Massage
Posada de Don Rodrigo Panajachel

Posada de Don Rodrigo Panajachel

Posada de Don Rodrigo Panajachel
3.5 star property
Panajachel
8.8 out of 10, Excellent, (440)
"beautiful views and great services "
United States
Rocio
The price is ₩262,870
₩320,701 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Posada de Don Rodrigo Panajachel
Property amenity
Regis Hotel & Spa

Regis Hotel & Spa

Regis Hotel & Spa
3.5 star property
Panajachel
8.8 out of 10, Excellent, (658)
"Nice place"
United States
Gerardo
The price is ₩88,909
₩115,812 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Regis Hotel & Spa
Sauna
Kula Maya Boutique Hotel & Spa

Kula Maya Boutique Hotel & Spa

Kula Maya Boutique Hotel & Spa
5.0 star property
San Marcos La Laguna
9.6 out of 10, Exceptional, (115)
"The staff were very friendly and polite, and the food was delicious! "
United States
Yessica
The price is ₩350,081
₩427,099 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Kula Maya Boutique Hotel & Spa
Exterior
Hotel y Cafe La Casa del Mundo

Hotel y Cafe La Casa del Mundo

Hotel y Cafe La Casa del Mundo
3.0 star property
Santa Cruz La Laguna
9.4 out of 10, Exceptional, (266)
"Excellent beautiful view "
United States
Luis
The price is ₩180,284
₩219,947 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel y Cafe La Casa del Mundo
Massages
Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul

Atitlan Oasis Eco Hotel and Spa Kaalpul
3.5 star property
San Antonio Palopo
8.6 out of 10, Excellent, (73)
"The location... The atmosphere"
United States
ewa
The price is ₩211,471
₩257,995 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Atitlan Oasis Eco Hotel and Spa Kaalpul
Family Quadruple Room, Garden View | Individually decorated, individually furnished, iron/ironing board
Hotel Toliman

Hotel Toliman

Hotel Toliman
3.0 star property
San Lucas Toliman
9.0 out of 10, Wonderful, (26)
"Lovely place to spend a few days away "
United States
Faye
The price is ₩83,539
₩117,265 total
includes taxes & fees
Dec 17 - Dec 18
Hotel Toliman
Exterior
Hotel Villa Santa Catarina

Hotel Villa Santa Catarina

Hotel Villa Santa Catarina
3.0 star property
Santa Catarina Palopo
9.0 out of 10, Wonderful, (307)
"Beautiful hotel and location! Definitely worth a stay here. One of our favorite hotels we stayed at in Lake Atitlan. "
United States
Lilly
Hotel Villa Santa Catarina
Luxury Studio | Pillowtop beds, minibar, laptop workspace, free WiFi
Refugio del Volcan

Refugio del Volcan

Refugio del Volcan
3.5 star property
San Pedro La Laguna
9.8 out of 10, Exceptional, (6)
"The place is in a safe area a little outside of the main town. The cabins are super cute and very clean. There is a main gate locks and it felt very secure. The walk up the path was tough with luggage ! This was my only complaint, but it was a great work out at the same time. Easy for backpackers but not a single lady with larger luggage. "
United States
Steve
Refugio del Volcan
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Panajachel Hotel Reviews

Porta Hotel del Lago

Porta Hotel del Lago

10/10 Excellent
"Fantastic place great location easy parking. Well, kept facilities. Very clean very safe and staff was very nice. It’s right in front of the lake so the views are fantastic. We got a lake view in the high floor. The staff was really nice. Very courteous. I definitely highly recommended. The restaurant is fantastic. They have an incredible dishes, especially the lomito . The staff was notifying me way ahead when I was going to get there and they were really accommodating to our needs. The suite was absolutely fabulous. I definitely. highly recommend this place. There’s so much to see and to walk all around the city the location as I mentioned before is incredible."
Ernesto 2-night trip
Posted 6 days ago
Porta Hotel del Lago

Frequently asked questions

Looking for a spa hotel in Panajachel?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers like the lakes and gardens in Panajachel so get ready to explore the great outdoors. Be sure to enjoy the shopping during your stay. Hotels with spas are the perfect way to break away from your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Panajachel?
Posada de Don Rodrigo Panajachel is a top spa hotel featuring a bar, an outdoor pool, and a restaurant. Enjoy a massage at the on-site spa. In-room massages are also available. Another popular spa hotel in Panajachel is Regis Hotel & Spa.
How many spa hotels will I find in Panajachel?
Among Expedia's 107 accommodation options in Panajachel, there are 2 spa hotels.
What's there to see and do in Panajachel?
Experience all that Panajachel has to offer when you visit Lake Atitlán, Casa Cakchiquel Arts Center, and Panajachel Municipal Market. If you have spare time during your trip, you might want to make a stop at Museo Raúl Vasquéz and La Galeria.
What is a Panajachel spa hotel?
Spa hotels in Panajachel provide lodging and have a full on-site spa offering services including therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.