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Check prices for these dates

Tonight
Dec 19 - Dec 20
Tomorrow
Dec 20 - Dec 21
This weekend
Dec 19 - Dec 21
Next weekend
Dec 26 - Dec 28

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Our top choices for Prague 21 hotels

Premium bedding, minibar, in-room safe, desk
Almanac X Alcron Prague

Almanac X Alcron Prague

Almanac X Alcron Prague
5.0 star property
Nové Město, 17.6 km from Prague 21
9.6 out of 10, Exceptional, (830)
"Clean room, amazing staff and amenities. Very spacious rooms and very easy check in and out. We loved our stay"
Australia
Holly
The price is ₩283,156
₩324,061 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Almanac X Alcron Prague
Staircase
Aurea Legends by Eurostars Hotel Company

Aurea Legends by Eurostars Hotel Company

Aurea Legends by Eurostars Hotel Company
4.0 star property
Nové Město, 18 km from Prague 21
9.8 out of 10, Exceptional, (181)
"Great Hotel"
Canada
Yitao
The price is ₩95,983
₩114,529 total
includes taxes & fees
Jan 19 - Jan 20, 2026
Aurea Legends by Eurostars Hotel Company
Lobby
The Dominican

The Dominican

The Dominican
4.0 star property
Stare Mesto, 18.1 km from Prague 21
9.4 out of 10, Exceptional, (883)
"Great area to stay ! Staff was very friendly "
Canada
Jonathan
The price is ₩144,493
₩168,930 total
includes taxes & fees
Jan 12 - Jan 13, 2026
The Dominican
Exterior
K+K Hotel Central Prague

K+K Hotel Central Prague

K+K Hotel Central Prague
4.0 star property
Nové Město, 17.3 km from Prague 21
9.2 out of 10, Wonderful, (1044)
"Hotel & breakfast "
United Kingdom
Delyth Lloyd
The price is ₩137,946
₩161,679 total
includes taxes & fees
Jan 18 - Jan 19, 2026
K+K Hotel Central Prague
City view
Grand Hotel Bohemia

Grand Hotel Bohemia

Grand Hotel Bohemia
5.0 star property
Stare Mesto, 17.6 km from Prague 21
9.6 out of 10, Exceptional, (1001)
"Staff was wonderful and the place was beautiful and clean!"
United States
Kimberly
The price is ₩210,506
₩242,760 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Grand Hotel Bohemia
Exterior
Hotel Hastal Prague Old Town

Hotel Hastal Prague Old Town

Hotel Hastal Prague Old Town
4.0 star property
Stare Mesto, 17.7 km from Prague 21
9.4 out of 10, Exceptional, (546)
"Wonderful hotel in Old Town Prague!"
United States
Daisuke
The price is ₩126,425
₩148,694 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Hastal Prague Old Town
Reception
Hotel Garden Court

Hotel Garden Court

Hotel Garden Court
4.0 star property
Nové Město, 18.1 km from Prague 21
9.2 out of 10, Wonderful, (562)
"Overall great location and wonderful stay. "
Canada
Dakota
The price is ₩119,632
₩140,878 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel Garden Court
Deluxe Terrace | Hypo-allergenic bedding, in-room safe, desk, laptop workspace
K+K Hotel Fenix

K+K Hotel Fenix

K+K Hotel Fenix
4.0 star property
Nové Město, 17.5 km from Prague 21
8.8 out of 10, Excellent, (1001)
"Great room great location very nice stuff!"
United States
Dvir
The price is ₩123,804
₩145,723 total
includes taxes & fees
Jan 11 - Jan 12, 2026
K+K Hotel Fenix
Front of property - evening/night
Boutique Hotel Constans

Boutique Hotel Constans

Boutique Hotel Constans
4.0 star property
Mala Strana, 19.5 km from Prague 21
9.4 out of 10, Exceptional, (701)
"Friendly staff great breakfast "
Canada
Janet
The price is ₩112,328
₩125,807 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Boutique Hotel Constans
Exterior
Hotel Villa

Hotel Villa

Hotel Villa
4.0 star property
13.6 km from Prague 21
9.2 out of 10, Wonderful, (221)
"Great hotel with a decent restaurant"
United States
Tafara
Hotel Villa
Reception
The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts

The Emblem Prague Hotel - Preferred Hotels & Resorts
5.0 star property
Stare Mesto, 18.2 km from Prague 21
9.4 out of 10, Exceptional, (1004)
"Ideal location for exploring Prague Old Town, Christmas Market and other sights."
United States
Mika
The price is ₩325,508
₩371,667 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Emblem Prague Hotel - Preferred Hotels & Resorts
Lobby
Hermitage Hotel Prague

Hermitage Hotel Prague

Hermitage Hotel Prague
4.5 star property
18.2 km from Prague 21
9.4 out of 10, Exceptional, (1000)
"Location is good; the breakfast is excellent; front desk personnel is super nice and professional"
United States
Wenzhou
The price is ₩118,643
₩139,986 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hermitage Hotel Prague
Reception
Pure White

Pure White

Pure White
4.0 star property
Vinohrady, 17.2 km from Prague 21
9.0 out of 10, Wonderful, (625)
"All of the above were great and it was easy and convenient to locate. "
United States
Alan
Pure White
Front of property
The Julius Prague

The Julius Prague

The Julius Prague
4.5 star property
Nové Město, 17.3 km from Prague 21
9.8 out of 10, Exceptional, (594)
"Great location Lovely staff Perfectly clean Great breakfast Very good room"
United States
Elisabeth
The price is ₩262,756
₩301,350 total
includes taxes & fees
Jan 7 - Jan 8, 2026
The Julius Prague
Classic Studio | Desk, laptop workspace, iron/ironing board, free WiFi
City Pop 2Night Prague - Self check-in

City Pop 2Night Prague - Self check-in

City Pop 2Night Prague - Self check-in
4.0 star property
Nové Město, 17.3 km from Prague 21
9.0 out of 10, Wonderful, (330)
"clean and modern amenities"
United Kingdom
Mae
The price is ₩96,056
₩114,688 total
includes taxes & fees
Jan 13 - Jan 14, 2026
City Pop 2Night Prague - Self check-in
Premium bedding, minibar, in-room safe, desk
Mandarin Oriental, Prague

Mandarin Oriental, Prague

Mandarin Oriental, Prague
5.0 star property
Mala Strana, 19.1 km from Prague 21
9.4 out of 10, Exceptional, (288)
"It was really an outstanding experience "
United States
ricardo
The price is ₩518,498
₩587,812 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Mandarin Oriental, Prague
Couples treatment rooms, massages
Mosaic House Design Hotel

Mosaic House Design Hotel

Mosaic House Design Hotel
4.0 star property
Nové Město, 18.2 km from Prague 21
9.8 out of 10, Exceptional, (717)
"Stupendous hotel, staff, attention to detail, the lot."
United Kingdom
Patricia
Mosaic House Design Hotel
Superior Room (Panoramic View) | Minibar, in-room safe, desk, laptop workspace
Hotel Clement

Hotel Clement

Hotel Clement
4.0 star property
Petrská čtvrť, 17.3 km from Prague 21
9.2 out of 10, Wonderful, (1000)
"Fantastic stay"
United States
Yaminiteja
The price is ₩109,894
₩130,144 total
includes taxes & fees
Jan 12 - Jan 13, 2026
Hotel Clement
Royal Double Room | Hypo-allergenic bedding, in-room safe, iron/ironing board, free WiFi
U Medvidku - Brewery Hotel

U Medvidku - Brewery Hotel

U Medvidku - Brewery Hotel
3.0 star property
Stare Mesto, 18.1 km from Prague 21
9.2 out of 10, Wonderful, (434)
"Very friendly and welcoming staff. Great beer and superb food. "
United Kingdom
Julian
U Medvidku - Brewery Hotel
Lobby
Occidental Praha Wilson

Occidental Praha Wilson

Occidental Praha Wilson
4.0 star property
Nové Město, 17.3 km from Prague 21
8.6 out of 10, Excellent, (343)
"Great hotel excellent location close to city center and all it has to offer. Clean spacious room very clean and quiet. "
United States
James
The price is ₩130,914
₩153,618 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Occidental Praha Wilson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Prague 21

Find the best Prague 21 areas and neighborhoods for the activities you enjoy most.
Charles Bridge featuring a bridge, a city and a river or creek

Prague City Center

Discover the medieval heart of Prague, a UNESCO World Heritage Site, featuring major attractions like Prague Castle, Old Town Square, and Charles Bridge. Explore the historic district, home to the Czech Parliament, government offices, and Charles University.

Czech Republic showing a city, a church or cathedral and heritage architecture

Stare Mesto

The geographical and historical heart of Prague, this UNESCO-listed district features a tangle of cobblestone streets lined by Baroque churches, palaces and houses.

Nove Mesto which includes heritage elements, railway items and a city

Nové Město

As the largest town in Prague's historic center, New Town boasts landmarks like Wenceslas Square, Dvořák Museum, and Dancing House. Explore its bustling commerce, vibrant tourism, and rich history.

Prague featuring a city

Prague 1

Known for its popular shops and acclaimed art galleries, there's plenty to explore in Prague 1. Check out top attractions like Old Town Square and Royal Route, and jump on the metro at Staromestska Station or Staroměstská Stop to see more of the city.

Nove Mesto showing a bay or harbor

Prague 2

Discover the medieval fortress ruins at Vyšehrad, stroll through Riegrovy sady in Vinohrady, or explore Charles Square's Gothic town hall. Easily navigate via I.P. Pavlova station and tramlines.

Top Prague 21 Hotel Reviews

Majestic Plaza Hotel Prague

Majestic Plaza Hotel Prague

10/10 Excellent
"Great location. Clean and spacious room. Varied breakfast choices Nice bar, with reasonablely price, great tasting food "
Heather 4-night trip
Posted 2 days ago
Majestic Plaza Hotel Prague

Frequently asked questions

What's it like in Prague 21?
Travelers will be sure to enjoy their time in Prague's Prague 21 neighborhood.
If I need to cancel my hotel reservation in Prague 21, will I receive a refund?
Yes! The majority of room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to get the best deals available in Prague 21.
Where can I learn more about changing or cancelling my trip to Prague 21?
To access more information about picking new dates or cancelling your trip to Prague 21, head over to our customer service page.
What can I see and do in this Prague neighborhood?
Some places to visit in the Prague area include House of the Black Madonna, Na Prikope, and Powder Tower so get out of the neighborhood to explore more of the city. While you're out sightseeing, Municipal House Hall and Estates Theatre are a couple of sights to visit.
How can I get around Prague 21 and the greater Prague area?
If you're considering venturing out of town, train travel is a great option. Prague-Klanovice Station is the closet train station, but Prague-Běchovice střed Station and Prague-Bechovice Station are also close by.