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Domus 21 Luxury Suites

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Luxury
VIP Access
1.401298464324817E-45 star property
9.8

Exceptional

Historic elegance in Rome's heart

Amidst Rome's Historic District, this boutique hotel offers a serene escape with modern, stylish interiors and ancient frescoes. Enjoy spacious rooms, luxurious bath products, and attentive service, all within walking distance of iconic landmarks like the Trevi Fountain and Pantheon.

Popular amenities

  • Pet friendly
  • Laundry
  • Housekeeping
  • Air conditioning
  • Free WiFi

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Room options

Available filters for rooms
Showing 4 of 4 rooms

View all photos for Superior Room, 1 Queen Bed, Courtyard View

Superior Room, 1 Queen Bed, Courtyard View | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Superior Room, 1 Queen Bed, Courtyard View

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Soundproofed
Individually furnished
Individually decorated
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
  • 20 sq m
  • Sleeps 3
  • 1 Queen Bed

View all photos for Deluxe Room, City View

Deluxe Room, City View | View from room

Deluxe Room, City View

9.6 out of 10
Exceptional
(4 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • 24 sq m
  • City view
  • Sleeps 2
  • 1 King Bed OR 2 Twin Beds

View all photos for Junior Suite

Junior Suite | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Junior Suite

10.0 out of 10
Exceptional
(3 reviews)

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • 40 sq m
  • City view
  • Sleeps 4
  • 1 King Bed

View all photos for Grand Room

Grand Room | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Grand Room

Highlights

Soundproofed
Air conditioning
Connecting rooms available
Free cribs/infant beds
Minibar (some free items)
Smart TV
Hypo-allergenic bedding
Pillow menu
  • 34 sq m
  • City view
  • Sleeps 3
  • 1 King Bed

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About the neighborhood

Map
Corso Vittorio Emanuele II 21, Rome, RM, 00186

What's nearby

  • Teatro Faiano - 1 min walk - 0.0 km
  • Piazza della Minerva - 2 min walk - 0.2 km
  • Santa Maria Sopra Minerva - 2 min walk - 0.2 km
  • Chiesa del Gesù - 2 min walk - 0.2 km
  • Largo di Torre Argentina - 2 min walk - 0.2 km

Getting around

  • Venezia Tram Stop - 4 min walk
  • Rome San Pietro Station - 5 min drive
  • Fiumicino - Leonardo da Vinci Intl. Airport (FCO) - 40 min drive

Restaurants

  • ‪Alice Pizza Largo Argentina - ‬1 min walk
  • ‪Rossopomodoro - ‬3 min walk
  • ‪Pizza e Mozzarella - ‬3 min walk
  • ‪PASTAEAT la pastapoke - ‬1 min walk
  • ‪Vini & Cucina Blasi - ‬4 min walk

About this property

Domus 21 Luxury Suites

Family-friendly guesthouse near Pantheon
A short walk from Campo de' Fiori and Piazza Navona, Domus 21 Luxury Suites provides dry cleaning/laundry services and more. Guests can connect to free in-room WiFi.
Other perks include:
  • A roundtrip airport shuttle (surcharge), an electric car charging station, and express check-out
  • Express check-in, tour/ticket assistance, and free newspapers
  • An elevator, bicycle parking, and smoke-free premises
  • Guest reviews speak highly of the helpful staff
Room features
All guestrooms at Domus 21 Luxury Suites have comforts such as premium bedding and pillow menus, in addition to thoughtful touches like laptop-compatible safes and air conditioning.
Extra amenities include:
  • Highchairs, children's books, and art supplies
  • Reusable coffee/tea filters, recycling, and LED light bulbs
  • Rainfall showers, designer toiletries, and bidets
  • Composting, eco-friendly cleaning products, and childcare services

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • In-room WiFi speed: 500+ Mbps (good for 6+ people or 10+ devices)
  • Available in some public areas: Free WiFi

Parking and transportation

  • Electric car charging station on site
  • Offsite parking within 1 mile (EUR 24 per day); discounts available
  • Street parking available
  • 24-hour roundtrip airport shuttle at scheduled times and on request for a surcharge

Food and drink

  • Couples/private dining
  • Private picnics

Things to do

  • Bicycle tours
  • Books
  • Helicopter/airplane tours
  • Private wine tours
  • Wine tours
  • Winery release events

Family friendly

  • Art supplies
  • Baby toys
  • Children's books
  • Children's games
  • Children's toys
  • High chair
  • In-room babysitting (surcharge)
  • In-room crib
  • Laundry facilities
  • Soundproofed rooms

Conveniences

  • Free newspapers in lobby
  • Guidebooks
  • Laundry facilities
  • Limited-hour front desk
  • Luggage storage

Guest services

  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Proposal/romance packages
  • Tour and ticket assistance
  • Turndown service

Business services

  • Coworking space

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible airport shuttle
  • Elevator
  • Well-lit path to entrance

More

  • At least 10% of profits reinvested in community and sustainability
  • At least 80% lighting from LEDs
  • Comprehensive food waste policy
  • Comprehensive recycling policy
  • Double-glazed windows
  • Humane treatment of captive wild animals
  • Local artist showcase
  • Local culture and ecosystem education
  • Locally-owned and organized tours and activities
  • Smoking not allowed

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Egyptian cotton sheets
  • Free crib
  • Hypo-allergenic bedding
  • Pillow menu
  • Pillowtop mattress

Bathroom

  • Bathrobes
  • Bidet
  • Designer toiletries
  • Hair dryer
  • Rainfall showerhead
  • Shampoo
  • Shower
  • Slippers
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Food and drink

  • Champagne service
  • Coffee/tea maker
  • Electric kettle
  • Espresso maker
  • Free bottled water
  • Free minibar (limited items)
  • Restaurant dining guides

More

  • Air conditioning
  • Cleaning products are eco-friendly
  • Composting
  • Connecting rooms available
  • Eco-friendly toiletries
  • Electrical adapters
  • Energy-saving switches in guestrooms
  • Free daily newspapers
  • Iron/ironing board on request
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Printer
  • Recycling
  • Reusable coffee/tea filters
  • Soundproofed rooms
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: 11:30 AM
Contactless check-in available
Express check-in available
Minimum check-in age: 15

Check-out

Check-out before 11:30 AM
Contactless check-out available
Express check-out available

Special check-in instructions

This property offers transfers from the airport (surcharges may apply); guests must contact the property with arrival details before travel, using the contact information on the booking confirmation
The front desk is open daily from 9:00 AM - 5:00 PM
Guests planning to arrive outside of normal check-in hours must contact the property in advance for check-in instructions and key retrieval information; front desk staffed during limited hours
To make arrangements for check-in please contact the property at least 24 hours before arrival using the information on the booking confirmation
If you are planning to arrive after 2:00 PM please contact the property in advance using the information on the booking confirmation

Access methods

Front desk (limited hours), key retrieval

Pets

Pets stay free
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
4 total (up to 22 lbs per pet)
Pets cannot be left unattended
Food and water bowls, pet-sitting services, litter boxes, and pet grooming services are available

Children and extra beds

Children are welcome
Rollaway/extra beds are not available
Free cribs are available on request at the property

Property payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • A tax is imposed by the city: EUR 5.00 per person, per night, up to 10 nights. This tax does not apply to children under 10 years of age.

We have included all charges provided to us by the property.

Optional extras

  • Airport shuttle fee: EUR 70 per vehicle (one-way, maximum occupancy 2)
  • Airport shuttle fee per child: EUR 70 (one-way), (from 10 to 18 years old)
  • Nearby parking fee: EUR 24 per day (3281 ft away)

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards, debit cards, and cash
Cashless transactions are available
Safety features at this property include a fire extinguisher, a security system, a first aid kit, and window guards
Property Registration Number IT058091B4OUIRD7WF

We should mention

All guests, including children, must be present at check-in and show their government-issued photo ID card or passport
Cash transactions at this property cannot exceed EUR 5000, due to national regulations; for further details, please contact the property using information in the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation

Property is also known as

Domus 21 Luxury Suites Rome
Domus 21 Luxury Suites Guesthouse
Domus 21 Luxury Suites Guesthouse Rome

Frequently asked questions

Is Domus 21 Luxury Suites pet-friendly?

Yes, this property allows cats and dogs (limit 4 total) with a maximum weight of up to 22 lbs per pet.

What time is check-in at Domus 21 Luxury Suites?

Check-in start time: 2:00 PM; Check-in end time: 11:30 AM.

What time is check-out at Domus 21 Luxury Suites?

Check-out is at 11:30 AM.

Does Domus 21 Luxury Suites provide a shuttle to the airport?

Yes, there's an airport shuttle that runs on request. A fee of EUR 70 per vehicle applies.

Where is Domus 21 Luxury Suites located?

This family-friendly Rome guesthouse is located near the airport, within a 5-minute walk of Corso Vittorio Emanuele II, Pantheon, and Piazza Venezia. Campo de' Fiori and Piazza Navona are also within 10 minutes. Venezia Tram Stop and Arenula-Cairoli Tram Station are within a 5-minute walk.

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Reviews

Domus 21 Luxury Suites Reviews

9.8

Exceptional

10

Cleanliness

9.4

Amenities

9.8

Staff & service

9.8

Eco-friendliness

9.6

Property conditions & facilities
Rating 10 - Excellent. 78 out of 92 reviews
Rating 8 - Good. 12 out of 92 reviews
Rating 6 - Okay. 1 out of 92 reviews
Rating 4 - Poor. 0 out of 92 reviews
Rating 2 - Terrible. 1 out of 92 reviews

Reviews

10/10 Excellent

Patrick

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great staff & location
Stayed 1 night in Oct 2025

10/10 Excellent

Deanna

Liked: Cleanliness, amenities, property conditions & facilities
Very lovely property! Close to so many restaurants, shopping, bus stops and site seeing.
Stayed 4 nights in Jun 2025

10/10 Excellent

diane

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This was a very unique and private property. The entrance was unsuspecting but easy to find. Once you went up the elevator and entered the guest services desk we were warmly welcomed. The room was very clean and the bed and linens very comfortable. We could not hear any street noise and had a pretty city view.
Stayed 3 nights in Sep 2025

10/10 Excellent

Jonathan

Liked: Cleanliness, staff & service, property conditions & facilities
Yes
Stayed 2 nights in Oct 2025

10/10 Excellent

Alexandra

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

10/10 recommend

Everything was amazing! We were at first a little confused on where to go once inside, but quickly figured it out and the concierge was so helpful in getting our bags into our room so we can go explore! We would def stay here again !
Stayed 1 night in Jul 2025

10/10 Excellent

Nhu

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This is exceptional space to spend time in Rome. The staff and rooms are superior. Their space is very aesthetic and the attention to detail in their design did not go unnoticed. I would not hesitate to stay here again! Thank you for the beautiful accommodations!
Stayed 1 night in Jun 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice staff. Great location
Stayed 1 night in Apr 2025

8/10 Good

Caitlyn

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The property is in an excellent location. Walkable to many dining options and close to a lot of sight seeing. The suites are a little hard to find once you arrive and you have to go up the oldest and smallest elevator which was an Experience in itself! more directions prior Would have been helpful but overall it’s a great place for a quick trip in Rome!
Stayed 2 nights in Jun 2025

10/10 Excellent

Jose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent location and service. Even though the hotel doesn't have a 24 hr reception, the staff is invaluable with anything, and the size of the room and location are superb.
Stayed 5 nights in Apr 2025

8/10 Good

Dennis

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location, location, location. Great restaurants all around. Walkable to Trevi, the Colosseum and Pantheon.
Stayed 3 nights in Mar 2025

10/10 Excellent

Yuri

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very good location and stylish
Stayed 2 nights in Nov 2024

10/10 Excellent

Mikeala

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Lovely size rooms that are really clean and quiet. Great location and friendly reception staff
Stayed 4 nights in Oct 2024

10/10 Excellent

Ira

Liked: Cleanliness, staff & service, property conditions & facilities
A five star experience in a well priced four star type property. Getting into place the first time is a bit of a challenge - street level passcode, up a flight of stairs to an old style elevator up to fifth floor - but once there, it's a lovely boutique property. Clean and front desk clerk very helpful.
Stayed 2 nights in May 2025

8/10 Good

Julie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Convenient, clean guesthouse in Rome.
Stayed 1 night in Jun 2024

10/10 Excellent

Robert Anthony

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location and very accommodating!
Stayed 6 nights in Apr 2023

10/10 Excellent

Gregory

Liked: Cleanliness, staff & service, property conditions & facilities
Overall this was superb. Clearer instructions on finding the reception would be an improvement.
Stayed 3 nights in Apr 2025

10/10 Excellent

Eusebio Dan

Liked: Cleanliness, staff & service, property conditions & facilities
Staff were kind and approachable! Location is amazing
Stayed 3 nights in May 2023

10/10 Excellent

Cynthia

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great location!

Nice place to stay! Perfect location, close to almost everything! Clean & very friendly staff. We would not hesitate to stay here again.
Stayed 2 nights in Jun 2023

10/10 Excellent

Angela

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Absolutely wonderful hotel. Unbelievably quiet and extremely convenient to all the major sites. The staff was excellent and easy to work with and we loved the beverages/snacks made available daily.

10/10 Excellent

Mert

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious, clean rooms in a historical building.
Stayed 1 night in Jul 2022

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful accommodations and top notch service by Gregorio and Jane. The hotel accommodations were lovely, the location was central and convenient, and definitely enhanced our stay in Rome.
Stayed 4 nights in Jul 2022

10/10 Excellent

zeline

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very nice rooms. good location. walkable to colusseum and many nice areas.
Stayed 3 nights in Mar 2024

10/10 Excellent

Sandra

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The location is ideal, centrally located in the historic center of Rome and immediately beside a busy taxi stand. Stepping inside the impressively large doors, one climbs a beautiful flight of stairs (shallow and easily managed) to the small lift. The office is on the top floor, number 5. Entering the double doors, the reception is immaculate, decor modern and inviting. Halls have intriguing
Stayed 1 night in Apr 2025

10/10 Excellent

Diana

Liked: Cleanliness, staff & service, property conditions & facilities
the staff was very attentive, nice, friendly, and welcoming, they also always made sure the room was always clean refilled my pear juice which was 10/10
Stayed 5 nights in Jul 2024

8/10 Good

Alison

Liked: Cleanliness, staff & service, property conditions & facilities
Fabulous location. Very quiet and peaceful room.
Stayed 4 nights in Sep 2023