Find hotels near San Sebastiano, Milan from ₩201,843

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Sebastiano hotels

Exterior
Oriana Homèl Milano

Oriana Homèl Milano

Oriana Homèl Milano
Centro Storico, 0.1 km from San Sebastiano
10.0 out of 10, Exceptional, (42)
"Perfect stay!"
Australia
Martin
The price is ₩224,171
₩278,564 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Oriana Homèl Milano
Lounge
Hotel Spadari Al Duomo

Hotel Spadari Al Duomo

Hotel Spadari Al Duomo
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.8 out of 10, Exceptional, (646)
"Best hotel in the best location with kind and attentive staff! Excellent breakfast. Comfortable bed. Bathroom (newly renovated) gorgeous! "
United States
Karen
The price is ₩488,825
₩571,367 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Hotel Spadari Al Duomo
Property entrance
Hotel Gran Duca Di York

Hotel Gran Duca Di York

Hotel Gran Duca Di York
3.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.6 out of 10, Exceptional, (548)
"Great location, quiet and friendly staff!"
United States
Anette
The price is ₩313,941
₩370,236 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel Gran Duca Di York
Elite Apartment, 2 Bedrooms, Balcony (Piazza Erculea 5) | Balcony
Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori

Heart Milan Apartments Duomo Missori
Centro Storico, 0.2 km from San Sebastiano
10.0 out of 10, Exceptional, (11)
"Great property and stay! The property was super communicative and met us at the apartment to give us the keys! The apartment was large with plenty of space, an awesome balcony, and comfy beds. The location was perfect - close to the Duomo and transpiration options (metro and tram stops) "
United States
Alison
The price is ₩252,092
₩309,546 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Heart Milan Apartments Duomo Missori
Royal Apartment, 3 Bedrooms, City View (Via Santa Maria Valle 7) | Terrace/patio
Heart Milan Apartments - San Sepolcro Duomo

Heart Milan Apartments - San Sepolcro Duomo

Heart Milan Apartments - San Sepolcro Duomo
Centro Storico, < 0.1 km from San Sebastiano
9.2 out of 10, Wonderful, (510)
"Beautiful place, amazing location. "
United States
Andre
The price is ₩228,646
₩283,487 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Heart Milan Apartments - San Sepolcro Duomo
Down comforters, minibar, in-room safe, blackout drapes
Speronari Suites

Speronari Suites

Speronari Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (205)
"Great location."
United States
Bruce
The price is ₩447,093
₩524,055 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Speronari Suites
Royal Luxury Suite Litta, Duomo View | Premium bedding, down comforters, pillowtop beds, minibar
AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites

AF Duomo - Milano Luxury Suites
Centro Storico, 0.3 km from San Sebastiano
9.8 out of 10, Exceptional, (29)
"Amazing view!!"
United States
Laura
The price is ₩1,161,821
₩1,325,126 total
includes taxes & fees
Jan 2 - Jan 3, 2026
AF Duomo - Milano Luxury Suites
Free daily buffet breakfast
Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite

Matilde Boutique Hotel, WorldHotels Elite
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (143)
"Great room, nice staff and breakfast. Concierge team was wonderful "
United States
Karrie Ellen
The price is ₩986,846
₩1,119,190 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Matilde Boutique Hotel, WorldHotels Elite
Interior entrance
Brera Apartments in City Center

Brera Apartments in City Center

Brera Apartments in City Center
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (29)
"We really enjoyed our stay. It was in a great location with so many restaurants and shopping nearby along with historical sites."
United States
Leann
The price is ₩219,780
₩391,542 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Brera Apartments in City Center
Exterior
Santa Marta Suites

Santa Marta Suites

Santa Marta Suites
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (158)
"Our stay was wonderful. The hotel is clean, close to everything and extremely quiet. The staff here is above wonderful. Niousha at the front desk went above and beyond. We cant say enough things about her. The breakfast is very good and plentiful. This is our second time here and will definitely be back."
United States
Mary
Santa Marta Suites
Breakfast and dinner served, international cuisine
The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts

The Square Milano Duomo - Preferred Hotels & Resorts
4.0 star property
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (1002)
"Very nice hotel, nice rooms, great friendly staff, very nice location."
United States
Reem
The price is ₩552,653
₩641,581 total
includes taxes & fees
Jan 6 - Jan 7, 2026
The Square Milano Duomo - Preferred Hotels & Resorts
Rooftop terrace
Prestige Boutique Homes Aparthotel Piazza Duomo View

Prestige Boutique Homes Aparthotel Piazza Duomo View

Prestige Boutique Homes Aparthotel Piazza Duomo View
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (47)
"Wonderful stay! The room was perfect and the view of the duomo was beautiful! The staff was outstanding and welcoming. Highly recommend!"
United States
Robert
The price is ₩298,459
₩581,591 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Prestige Boutique Homes Aparthotel Piazza Duomo View
Superior Double Room, Balcony, City View | Terrace/patio
Luxury Suite Milano Duomo

Luxury Suite Milano Duomo

Luxury Suite Milano Duomo
Centro Storico, 0.3 km from San Sebastiano
9.4 out of 10, Exceptional, (231)
"Beds were very comfortable, location was awesome "
United States
Nadia
The price is ₩334,145
₩399,535 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Luxury Suite Milano Duomo
Front of property - evening/night
Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan

Room Mate Collection Giulia, Milan
4.0 star property
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (1003)
"Excellent stay from start to finish ."
United States
Sergey
The price is ₩573,739
₩664,772 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Room Mate Collection Giulia, Milan
View from property
Santa Marta Suites

Santa Marta Suites

Santa Marta Suites
Centro Storico, 0.2 km from San Sebastiano
9.4 out of 10, Exceptional, (136)
"Amazing location, amazing staff! The hotel has 5 floors, each with a suite and a hotel style room. The top floor has a terrace with views of the city. We walked everywhere during our stay. The front desk staff was fantastic, as was the restaurant. Thank you so much for a great first trip to Milano!"
United States
Brittany
Santa Marta Suites
Terrace/patio
Milan Retreats Duomo

Milan Retreats Duomo

Milan Retreats Duomo
Centro Storico, 0.3 km from San Sebastiano
9.2 out of 10, Wonderful, (693)
"Great place and great apartment. I’ll come again "
United States
Mohammed
The price is ₩140,394
₩268,136 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Milan Retreats Duomo
Premium bedding, down comforters, memory foam beds, free minibar
ODSweet Duomo Milano Hotel

ODSweet Duomo Milano Hotel

ODSweet Duomo Milano Hotel
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.2 out of 10, Wonderful, (169)
"Great location with a nice rooftop. Great room and great staff. I recommend it. "
United States
VICTOR
The price is ₩558,982
₩648,540 total
includes taxes & fees
Jan 14 - Jan 15, 2026
ODSweet Duomo Milano Hotel
Exterior
Ostello Bello Milano Duomo

Ostello Bello Milano Duomo

Ostello Bello Milano Duomo
0.4 km from San Sebastiano
9.4 out of 10, Exceptional, (251)
"Everything was perfect. Awesome location. Friendly staff, would definitely stay again. "
United States
Youbi
The price is ₩174,313
₩201,843 total
includes taxes & fees
Jan 14 - Jan 15, 2026
Ostello Bello Milano Duomo
Reception
Casa Brivio

Casa Brivio

Casa Brivio
Centro Storico, 0.4 km from San Sebastiano
9.6 out of 10, Exceptional, (34)
"Memorable stay."
United States
Nabeel
Casa Brivio
Property entrance
Maison Milano | UNA Esperienze

Maison Milano | UNA Esperienze

Maison Milano | UNA Esperienze
4.0 star property
Centro Storico, 0.2 km from San Sebastiano
9.0 out of 10, Wonderful, (1003)
"Location, super helpful stuff, spacious room. Recommended."
United Kingdom
Alessio
The price is ₩470,772
₩551,508 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Maison Milano | UNA Esperienze
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top San Sebastiano Hotel Reviews

Hotels near other San Sebastiano attractions

Biblioteca Ambrosiana

One of Europe’s first public libraries is home to Leonardo da Vinci’s Codex Atlanticus, which is housed alongside a huge book and art collection.
See properties

Via Torino

During your visit to Milan, you can search for that perfect souvenir at Via Torino. Make time to visit the area's stunning cathedral, or simply enjoy its charming cafes.
See properties

Frequently asked questions

What's the area like around San Sebastiano?
San Sebastiano is located in a historic area of Milan known for its stunning cathedral and top museums. If you're looking for a convenient place to stay, check out the 1295 hotels and other accommodations you'll find within a mile.
What's the best place to stay near San Sebastiano?
Adjacent to San Sebastiano, Hotel Dei Cavalieri Milano Duomo is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a bar. Other good options within a short distance include Rosa Grand Milano - Starhotels Collezione and The Square Milano Duomo - Preferred Hotels & Resorts.
How many hotels are there close to San Sebastiano?
Expedia has 1295 hotels and other accommodations within a mile from San Sebastiano.
If I need to cancel the hotel reservation for my stay near San Sebastiano, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then use the "fully refundable" filter to get the best options available near San Sebastiano.
Where can I learn more about changing or cancelling my trip in the area near San Sebastiano?
To access more information about picking new dates or cancelling your stay near San Sebastiano, head over to our customer service page.
What can I see and do near San Sebastiano?
Museo del Novecento, Museo del Duomo, and Museo Poldi Pezzoli feature captivating exhibits. Sights like Cathedral of Milan, Biblioteca Ambrosiana, and Royal Palace of Milan are must-sees while exploring the area. You can check out the local talent at Teatro alla Scala, Teatro Dal Verme, and Teatro San Babila.
How can I get to San Sebastiano?
With so many choices for transportation, seeing all of the area near San Sebastiano is simple. You can access metro transit at Duomo Station, Via Orefici P.za Cordusio Tram Stop, and Cordusio M1 Tram Stop. If you're taking a train into town, Milan Cadorna Nord Station and Milan (XNC-Cadorna Train Station) are the closest stations to Milan Centre.