A calm lake with mountains in the background.

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Our top choices for Seneca hotels

1. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
Seneca
United States
Susana
₩143,702
₩158,072 total
includes taxes & fees
Sep 13 - Sep 14
Tru by Hilton Seneca Clemson

2. Lakeside Lodge Clemson

Lakeside Lodge Clemson
Seneca
United States
Christopher
₩111,049
₩141,233 total
includes taxes & fees
Sep 7 - Sep 8
Lakeside Lodge Clemson

3. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
Seneca
United States
Bryan
₩162,967
₩179,262 total
includes taxes & fees
Sep 27 - Sep 28
Fairfield Inn & Suites Seneca Clemson Univ Area

4. Quality Inn Seneca US-123

Quality Inn Seneca US-123
Seneca
United States
Anthony
₩102,695
₩121,141 total
includes taxes & fees
Sep 20 - Sep 21
Quality Inn Seneca US-123

5. Best Western Seneca-Clemson

Best Western Seneca-Clemson
Seneca
United States
Michelle
₩131,643
₩144,807 total
includes taxes & fees
Sep 15 - Sep 16
Best Western Seneca-Clemson

6. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
Seneca
United States
kendra
₩164,529
₩180,993 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn & Suites Seneca-Clemson Area

7. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
Seneca
United States
Rosario
₩111,389
₩122,528 total
includes taxes & fees
Sep 6 - Sep 7
Days Inn by Wyndham Seneca / Clemson Area

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
United States
Nirumol
₩126,331
₩198,733 total
includes taxes & fees
Oct 4 - Oct 5
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

9. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
Clemson
United States
Jennifer
₩151,801
₩168,509 total
includes taxes & fees
Sep 6 - Sep 7
Clemson University's James F. Martin Inn

10. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Robert
₩206,613
₩229,340 total
includes taxes & fees
Sep 7 - Sep 8
The Abernathy of Clemson

11. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
Clemson
United States
Anita
₩137,402
₩152,516 total
includes taxes & fees
Sep 27 - Sep 28
Comfort Inn & Suites Clemson - University Area

12. The Inn at Patrick Square

The Inn at Patrick Square
Clemson
United States
Christy
₩202,402
₩224,666 total
includes taxes & fees
Sep 6 - Sep 7
The Inn at Patrick Square

13. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
₩324,658
₩360,369 total
includes taxes & fees
Sep 6 - Sep 7
The Shepherd Hotel Downtown Clemson

14. Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
Anderson
United States
Mary
₩133,259
₩147,918 total
includes taxes & fees
Sep 13 - Sep 14
Fairfield Inn & Suites by Marriott Anderson Clemson

15. Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
Anderson
United States
Jessica
₩114,309
₩126,884 total
includes taxes & fees
Sep 7 - Sep 8
Microtel Inn & Suites by Wyndham Anderson/Clemson

16. Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
Anderson
United States
David
₩143,692
₩159,499 total
includes taxes & fees
Sep 21 - Sep 22
Hilton Garden Inn Anderson

17. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
Clemson
United States
Karen
₩137,402
₩152,516 total
includes taxes & fees
Sep 14 - Sep 15
Best Western Plus Clemson Hotel & Conference Center

18. Inn @ Clemson

Inn @ Clemson
Clemson
United States
Terry
₩108,808
₩120,776 total
includes taxes & fees
Sep 6 - Sep 7
Inn @ Clemson

19. Hampton Inn Anderson

Hampton Inn Anderson
Anderson
United States
ANNA
₩154,206
₩171,169 total
includes taxes & fees
Sep 13 - Sep 14
Hampton Inn Anderson

20. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Anderson
United States
Merret
₩139,915
₩155,306 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.

Downtown

Downtown Seneca captures the essence of small-town Southern charm with its well-preserved railroad heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colorful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railroad memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained vacation rentals rather than hotels. While dining options are limited within the neighborhood, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This neighborhood offers an authentic lakeside living experience without tourist crowds. Vacation rentals range from cozy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious sidewalks while listening to birdsong. Lake Keowee lies just beyond the neighborhood boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

A waterfall surrounded by autumn foliage.

High Falls County Park

Nestled along Lake Keowee with the Blue Ridge Mountains as backdrop, High Falls County Park offers pristine swimming and camping spots. Reserve waterfront campsites early to enjoy the park's serene natural setting.
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A grassy field with yellow flowers and trees in the foreground, with mountains in the background.

Blue Ridge Field

This historic park honors African-American education in Oconee County on the former Blue Ridge High School football grounds. Stroll the paved loop trail and explore community gardens in this peaceful green space.
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Oconee County Library Seneca Branch

This welcoming community hub offers reading materials, digital resources, and programs for all ages. Explore seasonal events like storytimes, trivia contests, and craft workshops in a tranquil learning environment.
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South Cove Park

This lakeside retreat on Lake Keowee offers pristine beaches, boat ramps, and scenic picnic spots. Enjoy fishing, swimming, or simply relaxing amid the natural beauty of upstate South Carolina.
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Friendship Recreation Area

After visiting Friendship Recreation Area, make a plan to see the other sights and activities in Seneca. Stroll along the lakeside or attend a sporting event in this family-friendly area.
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Seneca City Hall

Seneca City Hall is just one of the places to see in Seneca, so why not enjoy the other things to explore during your travels?
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The Gauntlet

You can enjoy a show at The Gauntlet during your stay in Seneca.
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World of Energy

This free educational center reveals the science of nuclear power through interactive exhibits and engaging displays. Explore the outdoor nature trail and butterfly garden for a complete energy learning experience.
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Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

See all hotels in Seneca
A calm lake with mountains in the background.

Top Seneca Hotel Reviews

Quality Inn Seneca US-123

Quality Inn Seneca US-123

8/10 Good
"Every thing was good"
Robert 4-night trip
Posted 19 hours ago
Quality Inn Seneca US-123
Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn

10/10 Excellent
"No complaints, very pretty atmosphere"
Kate 2-night trip
Posted 1 day ago
Clemson University's James F. Martin Inn
The Abernathy of Clemson

The Abernathy of Clemson

10/10 Excellent
"Easy, clean, and friendly!"
Laura Catherine 1-night trip
Posted 3 days ago
The Abernathy of Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

8/10 Good
"Enjoyed the stay, it was clean and would stay again"
Gerald 3-night trip
Posted 3 days ago
Best Western Plus Clemson Hotel & Conference Center
Quality Inn Clemson near University

Quality Inn Clemson near University

10/10 Excellent
"Everything was great"
Clarence 6-night trip
Posted 12 days ago
Quality Inn Clemson near University

More cheap stays in Seneca

Quality Inn Clemson near University

Quality Inn Clemson near University

3430 Clemson Blvd Anderson SC
₩71,710
₩79,598 total
Sep 30 - Oct 1
includes taxes & fees
Quality Inn Clemson near University
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

1007 George Smith Mill Rd Anderson SC
₩79,670
₩88,434 total
Sep 21 - Sep 22
includes taxes & fees
Days Inn by Wyndham Anderson
Inn @ Clemson

Inn @ Clemson

1303 Tiger Blvd Clemson SC
₩108,808
₩120,776 total
Sep 6 - Sep 7
includes taxes & fees
Inn @ Clemson
Lakeside Lodge Clemson

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC
₩111,049
₩141,233 total
Sep 7 - Sep 8
includes taxes & fees
Lakeside Lodge Clemson
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC
₩137,402
₩152,516 total
Sep 14 - Sep 15
includes taxes & fees
Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC
₩137,402
₩152,516 total
Sep 27 - Sep 28
includes taxes & fees
Comfort Inn & Suites Clemson - University Area

Find out more about Seneca

Top reasons to visit Seneca

  • Scenic Outdoor Adventures: Enjoy hiking, fishing, and exploring the natural beauty of Seneca Lake and the surrounding parks.
  • Cultural Experiences: Visit the Seneca Museum and participate in the vibrant Seneca Powwow for a taste of local heritage.
  • Charming Downtown: Stroll through the historic downtown area, featuring quaint shops and local eateries.
  • Golfing Opportunities: Tee off at excellent golf courses for a relaxing day outdoors.
  • Diverse Accommodations: Choose from cozy guesthouses to well-equipped hotels for a comfortable stay.

Find great hotels near Seneca

For a delightful stay in Seneca, South Carolina, you'll find a variety of accommodations to meet your needs, from cozy guesthouses to well-equipped hotels. Whether you're traveling for business, seeking a pet-friendly option, or planning a family vacation, Seneca offers a range of choices, including the Hampton Inn and the charming downtown Seneca bungalow. Explore your options to enjoy a comfortable and memorable experience in this picturesque town.

  • Best Western Plus Clemson Hotel & Conference Center: This budget-friendly hotel boasts a guest rating of 8.2 out of 10 and is located 11km from Seneca. It offers a welcoming atmosphere for both business travelers and those on a pet-friendly vacation. Guests appreciate the convenience of onsite amenities and the pet-friendly policy, which allows certain pets with applicable fees. With a focus on value and comfort, this property is a suitable choice for travelers seeking a reliable lodging option close to Clemson University.
  • Comfort Inn & Suites Clemson - University Area: Also rated 8.2 out of 10, this budget-friendly hotel is situated 11km from Seneca. It stands out for its accommodating environment for business travelers and pet owners alike. The hotel features policies that permit pets, including dogs and cats, along with waived fees for service animals. Guests enjoy a variety of amenities designed for comfort and convenience, making this property a solid option for those visiting the university area while needing a pet-friendly stay.
  • Inn @ Clemson: With a guest rating of 8.0 out of 10, the Inn @ Clemson provides a budget-conscious choice for travelers, located 11km from Seneca. This hotel emphasizes a professional environment, ideal for business travelers. While it may not have the same pet-friendly policies as other options, it offers essential amenities for a comfortable stay. Guests appreciate the convenient access to local attractions and the hotel's focus on providing a pleasant lodging experience for those on work-related trips.

Where to stay in and around Seneca

Experience the charm of Seneca, South Carolina, where outdoor adventures and stunning scenery await. Enjoy family-friendly activities and warm hospitality as you explore the historical downtown, featuring quaint shops and local eateries. Nearby, discover the picturesque beauty of Lake Hartwell and the vibrant atmosphere of Seneca Falls, New York. Whether hiking, fishing, or simply relaxing, Seneca promises a memorable getaway filled with nature and friendly faces.

  • Clemson: Located 11km from Seneca, Clemson is a vibrant city renowned for its rich culture and educational heritage. This college town attracts visitors year-round, with peak travel occurring from July to September. Travelers flock to Clemson for its outdoor activities, scenic views, and cultural experiences. Explore the historic Clemson University campus, enjoy a game at the local stadium, or take a leisurely stroll around Lake Hartwell. The city offers recreational areas and golf courses, making it a perfect destination for both relaxation and adventure.
  • Keowee: Nestled within the Seneca area, Keowee is a charming village that is ideal for nature lovers and couples seeking a romantic getaway. With a peak in visitor arrivals from July to August and October, this destination is perfect for outdoor enthusiasts. Keowee is famous for its stunning scenery, featuring beautiful lakes and lush landscapes. Visitors can enjoy various recreational activities, including hiking and golfing, and can explore the nearby historic college university and sports stadium. The serene ambiance makes it an excellent spot for relaxation and scenic enjoyment.
  • Normandy Shores: Also located close to Seneca, Normandy Shores is another picturesque village that captivates visitors with its outdoor beauty and romantic appeal. This destination sees an influx of travelers primarily from July to August and October. Normandy Shores is perfect for those who appreciate nature, offering scenic views and activities such as hiking and golfing. Key attractions include beautiful lakes, a historic college university, and access to a national state park. The tranquil environment and recreational opportunities make it a delightful stop for anyone seeking a peaceful retreat.

Things to do near Seneca

Shopping

In Seneca, you can enjoy shopping at local favorites like the Seneca Shopping Center, featuring a variety of stores. If you're up for a drive, visit the nearby Anderson Mall, approximately 24km away, where you’ll find numerous retail options and eateries to explore.

Recreation

At Serenity Spa, indulge in rejuvenating treatments that blend traditional techniques with modern wellness practices. For outdoor recreation, explore Lake Hartwell, offering opportunities for kayaking, fishing, and hiking amidst stunning landscapes, allowing for a refreshing connection with nature.

Adventure

Highlands Aerial Park is an exhilarating zipline and ropes course located 50km from Seneca. Experience the thrill of soaring through the treetops while enjoying breathtaking views of the surrounding landscape. It’s a great way to embrace the outdoors and connect with nature in an adventurous setting.

Nightlife

Seneca offers a laid-back nightlife with cozy pubs and local bars. Enjoy live music at places like The Spot on the Square, or sip craft beers at the Seneca Brewing Company. For a relaxed evening, unwind at the outdoor seating of local restaurants along Main Street.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in and around Seneca

Seneca, South Carolina, is an ideal destination for outdoor enthusiasts and those seeking scenic and romantic getaways. Visitors can explore diverse attractions, including urban parks, Seneca Lake, and historic sports stadiums. The area offers family-friendly activities and cultural experiences, with highlights such as the Seneca Museum and the beautiful Seneca River. Whether you're interested in history or nature, Seneca has something for everyone.

  • Highpointe Lower Field: This urban park in Seneca offers a welcoming atmosphere for families and outdoor enthusiasts. With ample green space, it's an ideal spot for picnics, leisurely walks, or simply enjoying the fresh air amidst the city vibes.
  • Lake Keowee: Located 14km from Seneca, Lake Keowee is a stunning destination known for its picturesque scenery and tranquil beaches. Perfect for a romantic getaway or a day of outdoor activities like swimming, kayaking, or fishing, it provides a serene escape from daily life.
  • Memorial Stadium: Situated 10km from Seneca, this historic sports stadium is a cultural hub where you can experience local sports events. The stadium's rich history adds to the excitement of cheering for the home team in a vibrant atmosphere.

Best time to go to Seneca

The best time to visit Seneca can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Seneca falls in July, when visitor numbers are slightly high and weather is mostly sunny with light rain. The coolest average temperature in Seneca falls in January, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January41.7°F (5.4°C)Light RainMostly SunnyAverageSlightly Low
February45.7°F (7.6°C)Light RainMostly SunnyAverageSlightly Low
March52.0°F (11.1°C)Light RainMostly SunnyAverageAverage
April59.9°F (15.5°C)Light RainMostly SunnyAverageAverage
May68.2°F (20.1°C)Light RainMostly SunnyAverageAverage
June75.7°F (24.3°C)Light RainMostly SunnySlightly HighAverage
July79.2°F (26.2°C)Light RainMostly SunnySlightly HighAverage
August77.4°F (25.2°C)Light RainMostly SunnyAverageAverage
September72.1°F (22.3°C)Light RainMostly SunnySlightly HighSlightly High
October62.1°F (16.7°C)Light RainMostly SunnySlightly LowSlightly High
November51.4°F (10.8°C)Light RainMostly SunnySlightly LowSlightly High
December45.7°F (7.6°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Seneca

Traveling to Seneca, South Carolina, is convenient with several nearby airports. Knoxville, TN (TYS-McGhee Tyson) is 156km away, with notable hotels like THE TENNESSEAN Hotel and Marriott Knoxville Downtown, both 18km from the airport. Asheville, NC (AVL-Asheville Regional), located 92km from Seneca, offers upscale stays at Grand Bohemian Lodge Asheville and The Inn on Biltmore Estate, both 14km from the airport. The closest option is Greenville, SC (GSP-Greenville-Spartanburg Intl.), just 71km away, featuring the Greenville Marriott and Hilton Greenville, which provide complimentary transportation services. Each airport offers various airlines to accommodate your travel needs.

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveler data. This hotel offers a restaurant and free parking. Other good options for your trip include Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy and Hampton Inn & Suites Seneca-Clemson Area. See all available top hotels, or vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
Where can I learn more about changing or cancelling my trip to Seneca?
To find more details about updating your trip to Seneca or cancelling it, click here.
What's the best place to stay for a family vacation to Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.
What's the best LGBTQ-friendly place to stay in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best pet-friendly accommodation in Seneca?
Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Quality Inn Seneca US-123. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Hampton Inn & Suites Seneca-Clemson Area and Fairfield Inn & Suites Seneca Clemson Univ Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.
What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?
Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.
What is staying in Seneca like?
Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 320 hotels and other accommodations to choose from. Find out more about Seneca.
What should I do while I'm visiting Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.
What's the weather like in Seneca?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.

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