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Find hotels in Southeast Missouri, MO from ₩82,472
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Our top choices for Southeast Missouri hotels
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Room was spotless, staff was SO kind. 5 day trip, stayed in 4 different hotels & this one was BY FAR the nicest. Breakfast was fabulous. 10 out of 10 recommend!! "
Brenda
The price is ₩121,609
₩128,569 total
includes taxes & fees
Jan 25 - Jan 26
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.8 out of 10, Excellent, (472 reviews)
"Clean room, very nice staff"
Mack
The price is ₩111,728
₩127,062 total
includes taxes & fees
Jan 30 - Jan 31
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,006 reviews)
"Great place "
Kelly
The price is ₩131,866
₩148,747 total
includes taxes & fees
Jan 25 - Jan 26
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
7.8 out of 10, Good, (1,000 reviews)
"Clean room/friendly staff "
Sloan
The price is ₩83,796
₩88,383 total
includes taxes & fees
Jan 19 - Jan 20
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (979 reviews)
"Great location and room "
Curtis
The price is ₩152,876
₩172,708 total
includes taxes & fees
Feb 6 - Feb 7
Echo Bluff State Park
Echo Bluff State ParkEminence
9.4 out of 10, Exceptional, (219 reviews)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
Joanne
The price is ₩240,316
₩254,074 total
includes taxes & fees
Jan 18 - Jan 19
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (864 reviews)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
Brenda
The price is ₩152,449
₩172,229 total
includes taxes & fees
Jan 31 - Feb 1
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (798 reviews)
"Staff was kind and provided a lot of information during check out."
Shea
The price is ₩159,227
₩178,295 total
includes taxes & fees
Feb 14 - Feb 15
Best Western Plus Sikeston
Best Western Plus SikestonSikeston
8.4 out of 10, Very Good, (1,002 reviews)
"Great stay, everything was clean and comfortable. "
Charles
The price is ₩104,950
₩119,616 total
includes taxes & fees
Jan 25 - Jan 26
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (551 reviews)
"lean, updated rooms, friendly staff and great breakfast."
Linda
The price is ₩133,779
₩153,142 total
includes taxes & fees
Jan 18 - Jan 19
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,002 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
Nicole
The price is ₩138,175
₩158,859 total
includes taxes & fees
Jan 21 - Jan 22
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (730 reviews)
"Clean room and easy access to room"
Anne
The price is ₩81,576
₩92,975 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (714 reviews)
"Amazing place"
Mladen
The price is ₩161,711
₩182,719 total
includes taxes & fees
Jan 24 - Jan 25
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (336 reviews)
"Staff was very friendly."
Joyce
The price is ₩132,294
₩143,423 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (688 reviews)
"Conveniently located, clean, friendly staff."
Philip
The price is ₩117,095
₩126,726 total
includes taxes & fees
Jan 25 - Jan 26
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (151 reviews)
"Great hotel - super clean, fast check-in, convenient, etc.
We’ll definitely stay here again. "
Richard
The price is ₩128,950
₩145,473 total
includes taxes & fees
Jan 25 - Jan 26
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
"clean room, comfy bedding, nice staff, convenient location "
Alexa
The price is ₩148,848
₩168,533 total
includes taxes & fees
Feb 1 - Feb 2
Pear Tree Inn Cape Girardeau Near the Medical Center
Pear Tree Inn Cape Girardeau Near the Medical CenterCape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Staff great. "
Nancy
The price is ₩180,808
₩203,977 total
includes taxes & fees
Jan 18 - Jan 19
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very Good, (905 reviews)
"Breakfast was great!
Location right off interstate was perfect.
The property is a little old."
Mindy
The price is ₩134,955
₩154,322 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHGFestus
9.4 out of 10, Exceptional, (706 reviews)
"Clean room and great staff"
Stacy
The price is ₩178,771
₩204,425 total
includes taxes & fees
Feb 15 - Feb 16
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cottage
40-acre Poplar Bluff Nature Lovers Paradise!
40-acre Poplar Bluff Nature Lovers Paradise!Poplar Bluff
10.0 out of 10, Exceptional, (3 reviews)
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Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Lake Wappapello State Park.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Cape Girardeau
10/10 Excellent
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ₩77,621 per night from Jan 25 to Jan 26
₩77,621
₩88,371 total
Jan 25 - Jan 26
includes taxes & fees
7.8/10 Good! (1,000 reviews)
Hotels in Southeast Missouri with star-rating
4 Star Hotels
2 properties
