Southeast Missouri, MO

Travel Guide

Southeast Missouri
Southeast Missouri
Southeast Missouri
Photo by Jessica Richter
Photo by Jessica Richter
Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 out of 5
1625 W Columbia St, Farmington, MO
Fully refundableReserve now, pay when you stay
The price is ₩72,470 per night from Sep 21 to Sep 22
₩72,470
₩82,508 total
Sep 21 - Sep 22
includes taxes & fees
Book a stay at this business-friendly hotel in Farmington. Enjoy free breakfast, free parking, and an outdoor pool. Our guests praise the breakfast and the helpful ...
8/10 Very Good! (1,002 reviews)
"Front desk employee very helpful and managed to get us into ground floor room since we have some mobility issues."

Reviewed on Sep 10, 2025

Baymont Inn and Suites by Wyndham Farmington, MO
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is ₩125,415 per night from Sep 21 to Sep 22
₩125,415
₩141,470 total
Sep 21 - Sep 22
includes taxes & fees
Stay at this 3-star business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,001 reviews)
"Allowing the guests to use the gym 24/7; would be extremely appreciated."

Reviewed on Sep 10, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
The price is ₩146,752 per night from Sep 16 to Sep 17
₩146,752
₩165,557 total
Sep 16 - Sep 17
includes taxes & fees
Book a stay at this business-friendly hotel in Cape Girardeau. Enjoy free WiFi, free parking, and 2 restaurants. Popular attractions Isle Casino Cape Girardeau ...
9.2/10 Wonderful! (413 reviews)
"Staff was welcoming. Room very nice & clean. The bed spotlights did not work on my bed, the other bed's did work."

Reviewed on Sep 9, 2025

The Riverview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 out of 5
4800 U.S. Highway 67, De Soto, MO
Stay at this 3.5-star family-friendly aparthotel in De Soto. Enjoy free parking, an outdoor pool, and a fitness center. Our guests praise the property condition ...
9.4/10 Exceptional! (152 reviews)
2Bd/2Ba Room at Timber Creek Resorts
"Very nice resort and accommodations were fantastic!! My young nephews loved the jetted tub. 2 bedrooms were spacious and the back balcony was wonderful to relax for the evening. Unique extra kitchenette in the Queen bedroom!! I would highly recommend and would return again."

Reviewed on Sep 9, 2025

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Postcard Cabins St. Francois

Postcard Cabins St. Francois

2 out of 5
7555 State Hwy Y, French Village, MO
Stay at this cabin in French Village. Enjoy free parking, patios, and climate control.
9.8/10 Exceptional! (30 reviews)
"My first time staying at the post card cabins with my spouse and we absolutely loved it. The communication from the time i booked until check out was amazing. Provided all the details needed. We felt very safe and enjoyed no phones and tv for two days. Very clean cabin. All needed toiletries was ..."

Reviewed on Aug 27, 2025

Postcard Cabins St. Francois
Lake Wappapello

Lake Wappapello

2 out of 5
8005 Missouri 172, Williamsville, MO
Stay at this cabin in Williamsville. Enjoy free parking. Popular attractions North Main Street Historic District and Margaret Harwell Art Museum are located ...
Lake Wappapello
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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