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Find hotels in Southeast Missouri, MO from ₩84,459
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Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,001 reviews)
The price is ₩153,397
₩176,369 total
includes taxes & fees
May 4 - May 5

Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (536 reviews)
The price is ₩156,937
₩177,691 total
includes taxes & fees
May 14 - May 15

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (746 reviews)
The price is ₩131,432
₩142,243 total
includes taxes & fees
Apr 20 - Apr 21

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
The price is ₩162,247
₩183,046 total
includes taxes & fees
May 10 - May 11

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (346 reviews)
The price is ₩140,438
₩152,245 total
includes taxes & fees
Apr 18 - Apr 19

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ₩154,887
₩174,727 total
includes taxes & fees
Apr 26 - Apr 27

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (888 reviews)
The price is ₩161,948
₩182,961 total
includes taxes & fees
Apr 29 - Apr 30

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
8.0 out of 10, Very Good, (1,001 reviews)
The price is ₩107,474
₩113,348 total
includes taxes & fees
Apr 22 - Apr 23

Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
8.4 out of 10, Very Good, (980 reviews)
The price is ₩102,815
₩117,697 total
includes taxes & fees
May 3 - May 4

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (71 reviews)
The price is ₩162,262
₩183,722 total
includes taxes & fees
May 10 - May 11

Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti CaruthersvilleHayti
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ₩156,347
₩178,197 total
includes taxes & fees
Apr 22 - Apr 23

Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.2 out of 10, Very Good, (60 reviews)
The price is ₩106,208
₩121,315 total
includes taxes & fees
May 17 - May 18

Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
8.4 out of 10, Very Good, (1,004 reviews)
The price is ₩132,745
₩151,295 total
includes taxes & fees
Apr 19 - Apr 20

Madison Inn Lodge
Madison Inn LodgeFredericktown
7.6 out of 10, Good, (298 reviews)
The price is ₩128,837
₩140,733 total
includes taxes & fees
Apr 25 - Apr 26

Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
9.0 out of 10, Wonderful, (606 reviews)
The price is ₩175,538
₩191,086 total
includes taxes & fees
Apr 19 - Apr 20

Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
8.6 out of 10, Excellent, (458 reviews)
The price is ₩148,986
₩168,690 total
includes taxes & fees
May 3 - May 4

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,000 reviews)
The price is ₩154,872
₩174,966 total
includes taxes & fees
May 10 - May 11

Current River Inn
Current River InnVan Buren
8.2 out of 10, Very Good, (170 reviews)
The price is ₩160,639
₩173,841 total
includes taxes & fees
Apr 19 - Apr 20

Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (310 reviews)
The price is ₩159,003
₩173,667 total
includes taxes & fees
Apr 19 - Apr 20

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very Good, (766 reviews)
The price is ₩96,418
₩109,891 total
includes taxes & fees
Apr 29 - Apr 30
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (59 reviews)
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