Find hotels in Southeast Missouri, MO from ₩84,459

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southeast Missouri hotels

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1,001 reviews)
"Very nice for overnight stay"
United States
Scott
The price is ₩153,397
₩176,369 total
includes taxes & fees
May 4 - May 5
Drury Inn & Suites Sikeston, MO

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (536 reviews)
"Great stay"
United States
grant
The price is ₩156,937
₩177,691 total
includes taxes & fees
May 14 - May 15
Hampton Inn Sikeston

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (746 reviews)
"Very clean and staff was very nice"
United States
Nastassia
The price is ₩131,432
₩142,243 total
includes taxes & fees
Apr 20 - Apr 21
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
"Great room, staff and breakfast! "
United States
Kenneth
The price is ₩162,247
₩183,046 total
includes taxes & fees
May 10 - May 11
Drury Plaza Hotel Cape Girardeau Conference Center

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (346 reviews)
"It was a very nice hassle free stay. I will be staying here again."
United States
Michael Grey
The price is ₩140,438
₩152,245 total
includes taxes & fees
Apr 18 - Apr 19
Honeysuckle Inn - Mountain View

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1,000 reviews)
"This was probably the cleanest hotel we have ever stayed in. The beds were also very comfortable. Staff was also friendly and helpful."
United States
Amber
The price is ₩154,887
₩174,727 total
includes taxes & fees
Apr 26 - Apr 27
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (888 reviews)
"Staff is Great , Room very clean and well stocked ."
United States
joan
The price is ₩161,948
₩182,961 total
includes taxes & fees
Apr 29 - Apr 30
Fairfield Inn & Suites by Marriott Poplar Bluff

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very Good, (1,001 reviews)
"Overall stay was convenient."
United States
Salman Mahmud
The price is ₩107,474
₩113,348 total
includes taxes & fees
Apr 22 - Apr 23
Motel 6 Poplar Bluff, MO

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very Good, (980 reviews)
"Great place to stay"
United States
Doug
The price is ₩102,815
₩117,697 total
includes taxes & fees
May 3 - May 4
Super 8 by Wyndham Perryville

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (71 reviews)
"Nice quiet hotel "
United States
Steven
The price is ₩162,262
₩183,722 total
includes taxes & fees
May 10 - May 11
Fairfield Inn & Suites by Marriott Sikeston

Drury Inn & Suites Hayti Caruthersville

Drury Inn & Suites Hayti Caruthersville
3.0 star property
Hayti
9.4 out of 10, Exceptional, (1,000 reviews)
"Hotel was clean, comfortable, and a great stay off interstate! Staff was friendly"
United States
Rhian
The price is ₩156,347
₩178,197 total
includes taxes & fees
Apr 22 - Apr 23
Drury Inn & Suites Hayti Caruthersville

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.2 out of 10, Very Good, (60 reviews)
"The property is beautiful! The rooms are terrific! Staff is amazing! Totally recommend!! "
United States
Sue
The price is ₩106,208
₩121,315 total
includes taxes & fees
May 17 - May 18
Super 8 By Wyndham Marston

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1,004 reviews)
"Very nice folks who manage the hotel!!"
United States
Jane
The price is ₩132,745
₩151,295 total
includes taxes & fees
Apr 19 - Apr 20
Best Western Plus Sikeston I-55

Madison Inn Lodge

Madison Inn Lodge
2.5 star property
Fredericktown
7.6 out of 10, Good, (298 reviews)
"Rooms were clean! Beds were comfortable, and the staff were very accommodating."
United States
Ashley
The price is ₩128,837
₩140,733 total
includes taxes & fees
Apr 25 - Apr 26
Madison Inn Lodge

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (606 reviews)
"Excellent staff and location was nice and quiet "
United States
Colleen
The price is ₩175,538
₩191,086 total
includes taxes & fees
Apr 19 - Apr 20
Crown Pointe Lodge, BW Signature Collection

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (458 reviews)
"Clean rooms, friendly staff and convenient location."
United States
Mark
The price is ₩148,986
₩168,690 total
includes taxes & fees
May 3 - May 4
Holiday Inn Express & Suites Sikeston Southwest by IHG

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean, comfortable room and great staff!"
United States
Kendra
The price is ₩154,872
₩174,966 total
includes taxes & fees
May 10 - May 11
Drury Inn & Suites Poplar Bluff

Current River Inn

Current River Inn
3.0 star property
Van Buren
8.2 out of 10, Very Good, (170 reviews)
"The room was very clean. The desk help was very good, pleasant, and informative."
United States
Frank
The price is ₩160,639
₩173,841 total
includes taxes & fees
Apr 19 - Apr 20
Current River Inn

Shepherd Mountain Inn

Shepherd Mountain Inn
2.5 star property
Ironton
9.2 out of 10, Wonderful, (310 reviews)
"Every thang was awsome and it has been the nicest place we have stayed very well taken care of"
United States
Terry
The price is ₩159,003
₩173,667 total
includes taxes & fees
Apr 19 - Apr 20
Shepherd Mountain Inn

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (766 reviews)
"Very nice place, very nice stay! They were out of cream cheese for the bagels at breakfast though.:-)"
United States
Mark
The price is ₩96,418
₩109,891 total
includes taxes & fees
Apr 29 - Apr 30
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southeast Missouri

Save an average of 15% on thousands of hotels when you're signed in

Top Southeast Missouri Hotel Reviews

Hotels in Southeast Missouri with star-rating