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Find hotels in Southeast Missouri, MO from ₩86,138
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Our top choices for Southeast Missouri hotels

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (75 reviews)
The price is ₩163,987
₩241,203 total
includes taxes & fees
Jun 14 - Jun 15

Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,008 reviews)
The price is ₩121,038
₩127,968 total
includes taxes & fees
Jun 8 - Jun 9

Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (193 reviews)
The price is ₩140,195
₩158,160 total
includes taxes & fees
Jul 2 - Jul 3

Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (131 reviews)
The price is ₩146,806
₩167,086 total
includes taxes & fees
Jun 21 - Jun 22

Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
8.0 out of 10, Very Good, (1,009 reviews)
The price is ₩93,879
₩102,187 total
includes taxes & fees
Jun 8 - Jun 9

The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (587 reviews)
The price is ₩199,041
₩224,547 total
includes taxes & fees
Jun 9 - Jun 10

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,011 reviews)
The price is ₩165,477
₩186,690 total
includes taxes & fees
Jun 28 - Jun 29

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
La Quinta Inn & Suites by Wyndham Festus - St. Louis SouthFestus
8.0 out of 10, Very Good, (991 reviews)
The price is ₩126,601
₩144,769 total
includes taxes & fees
Jun 16 - Jun 17

Current River Inn
Current River InnVan Buren
8.2 out of 10, Very Good, (176 reviews)
The price is ₩163,837
₩177,302 total
includes taxes & fees
Jun 8 - Jun 9

Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
9.8 out of 10, Exceptional, (36 reviews)
The price is ₩158,459
₩177,931 total
includes taxes & fees
Jun 21 - Jun 22

Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (858 reviews)
The price is ₩164,709
₩184,432 total
includes taxes & fees
Jun 14 - Jun 15

Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,005 reviews)
The price is ₩167,947
₩193,097 total
includes taxes & fees
Jun 14 - Jun 15

Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (84 reviews)
The price is ₩166,449
₩188,462 total
includes taxes & fees
Jun 21 - Jun 22

Lake Wappapello
Lake WappapelloWilliamsville
10.0 out of 10, Exceptional, (2 reviews)
The price is ₩115,092
₩121,393 total
includes taxes & fees
Jun 14 - Jun 15

New Orleans Inn Portageville
New Orleans Inn PortagevillePortageville
8.0 out of 10, Very Good, (767 reviews)
The price is ₩85,303
₩92,103 total
includes taxes & fees
Jun 7 - Jun 8

Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (359 reviews)
The price is ₩148,943
₩161,471 total
includes taxes & fees
Jun 7 - Jun 8

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (1,005 reviews)
The price is ₩142,223
₩160,676 total
includes taxes & fees
Jun 7 - Jun 8

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (776 reviews)
The price is ₩140,195
₩151,726 total
includes taxes & fees
Jun 4 - Jun 5

The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (555 reviews)
The price is ₩142,925
₩162,542 total
includes taxes & fees
Jun 10 - Jun 11

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (909 reviews)
The price is ₩166,449
₩188,045 total
includes taxes & fees
Jun 14 - Jun 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southeast Missouri
Cabin

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (75 reviews)
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Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Clearwater Lake.

Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
More cheap stays in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is ₩93,879 per night from Jun 8 to Jun 9
₩93,879
₩102,187 total
Jun 8 - Jun 9
includes taxes & fees
8/10 Very Good! (1,009 reviews)
Hotels in Southeast Missouri with star-rating

4 Star Hotels
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