Find hotels in Southeast Missouri, MO from ₩87,492
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Tonight
Sep 1 - Sep 2Tomorrow
Sep 2 - Sep 3This weekend
Sep 4 - Sep 6Next weekend
Sep 11 - Sep 13Our top choices for Southeast Missouri hotels
1. Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
David
₩132,657
₩151,859 total
includes taxes & fees
Sep 6 - Sep 7
2. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Sandra
₩136,746
₩154,268 total
includes taxes & fees
Sep 6 - Sep 7
3. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Scott Andrew
₩129,362
₩148,735 total
includes taxes & fees
Sep 14 - Sep 15
4. Super 8 by Wyndham Potosi
Super 8 by Wyndham PotosiPotosi
Ross
₩79,622
₩86,967 total
includes taxes & fees
Sep 6 - Sep 7
5. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
Raidas
₩98,454
₩111,069 total
includes taxes & fees
Sep 6 - Sep 7
6. Madison Inn Lodge
Madison Inn LodgeFredericktown
Lori
₩119,679
₩130,729 total
includes taxes & fees
Sep 11 - Sep 12
7. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Allen
₩138,128
₩156,396 total
includes taxes & fees
Sep 13 - Sep 14
8. Perryville RV Resort
Perryville RV ResortPerryville
Von
₩90,809
₩103,953 total
includes taxes & fees
Sep 2 - Sep 3
9. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
Kristin
₩171,087
₩193,866 total
includes taxes & fees
Sep 13 - Sep 14
10. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
Susan
₩149,957
₩163,228 total
includes taxes & fees
Sep 2 - Sep 3
11. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
ELAINE
₩138,128
₩157,209 total
includes taxes & fees
Sep 7 - Sep 8
12. The Riverview
The RiverviewCape Girardeau
Alyssa
₩156,316
₩176,346 total
includes taxes & fees
Sep 2 - Sep 3
13. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Jamie
₩114,222
₩120,761 total
includes taxes & fees
Sep 21 - Sep 22
14. Super 8 by Wyndham Perryville
Super 8 by Wyndham PerryvillePerryville
Elizabeth
₩96,484
₩110,450 total
includes taxes & fees
Sep 9 - Sep 10
15. Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
JOAQUIN
₩135,392
₩146,784 total
includes taxes & fees
Sep 5 - Sep 6
16. Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
ILUNGA
₩80,378
₩87,492 total
includes taxes & fees
Sep 13 - Sep 14
17. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
Arsenia
₩138,333
₩156,283 total
includes taxes & fees
Sep 13 - Sep 14
18. Best Western Plus Sikeston I-55
Best Western Plus Sikeston I-55Sikeston
Kevin
₩119,460
₩136,155 total
includes taxes & fees
Sep 2 - Sep 3
19. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
Shawn
₩126,708
₩137,130 total
includes taxes & fees
Sep 2 - Sep 3
20. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
Rebekah
₩144,665
₩163,203 total
includes taxes & fees
Sep 13 - Sep 14
Vacation Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
"I really enjoyed my time at the stay !"
Cottage
'turtle Rock' - Ironton Cabin w/ Furnished Patio!
'turtle Rock' - Ironton Cabin w/ Furnished Patio!Ironton
"Stroller, pack n play and high chair. This was amazing "
Aparthotel
The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
Vacation Home
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
Cottage
Walk to Current River: Ozarks Adventure Home!
Walk to Current River: Ozarks Adventure Home!Van Buren
"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."
Cottage
Cozy Belgrade Cottage w/ Wood-burning Stove!
Cozy Belgrade Cottage w/ Wood-burning Stove!Belgrade
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Stay near popular Southeast Missouri attractions
Photo by Pat Long
Elephant Rocks State Park
9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.
Current River State Park
9.2/10 (20 reviews)
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.
Century Casino Caruthersville
7.0/10 (57 reviews)
Why not roll the dice with a visit to Century Casino Caruthersville during your travels in Caruthersville? While in this family-friendly area, you can enjoy the restaurants.
Learn more about Southeast Missouri
Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from K Bridge Recreation Area to Clearwater Lake.
See all hotels in Southeast Missouri
Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"Front desk was welcoming and nice. Room was cleaned, beds were comfy. Very spacious. Quiet as well."
The Riverview
10/10 Excellent
"My stay was wonderful and the food was good"
Holiday Inn Poplar Bluff by IHG
8/10 Good
"Everything was good, the only issue I had. Was served the wrong breakfast . Then charged $18.00 for the difference. But the restaurant was busy. So I paid and never said anything. Including the ham I got that I don’t eat."
Drury Inn & Suites Sikeston, MO
8/10 Good
"Had a very nice stay for one night while traveling. Room was clean and comfortable."
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
10/10 Excellent
"Nice customer service. I liked the access to washer and dryer, as well as cookies being served in the evening. I like the indoor pool and the gym. Is closed to many restaurants and showing mall."
Motel 6 Poplar Bluff, MO
10/10 Excellent
"The room was clean and the bed was comfortable. It was also quiet making it easy to get some sleep before getting back on the road."
More cheap stays in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
₩80,378
₩87,492 total
Sep 13 - Sep 14
includes taxes & fees
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
₩89,509
₩102,018 total
Sep 3 - Sep 4
includes taxes & fees
7.2/10 Good! (1,003 reviews)
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
₩92,067
₩107,581 total
Sep 21 - Sep 22
includes taxes & fees
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
₩108,040
₩120,991 total
Sep 2 - Sep 3
includes taxes & fees
8/10 Very Good! (1,002 reviews)
The Farmstead Hotel
778 E 3rd St Caruthersville MO
₩129,922
₩147,754 total
Sep 2 - Sep 3
includes taxes & fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
₩138,128
₩157,209 total
Sep 7 - Sep 8
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Hotels in Southeast Missouri with star-rating
4 Star Hotels
2 properties
3 Star Hotels
70 properties
2 Star Hotels
90 properties
