The Best Luxury Hotels in Southern Minnesota, MN from ₩164,150 in 2026

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Our top choices for Southern Minnesota luxury hotels

The Towers At Kahler Grand Hotel

Downtown Rochester

₩630,646 total

includes taxes & fees

Jun 19 - Jun 20

EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park

₩226,612 total

includes taxes & fees

Jun 21 - Jun 22

DoubleTree by Hilton Austin, MN

Austin

₩164,150 total

includes taxes & fees

Jun 29 - Jun 30

DoubleTree by Hilton Owatonna

Owatonna

₩197,739 total

includes taxes & fees

Jun 30 - Jul 1

The Charmant Hotel

Historic Downtown La Crosse

Elegant riverside sophistication awaits at this historic La Crosse hotel with pillowtop beds, rainfall showers, and two bars.

₩315,991 total

includes taxes & fees

Jun 21 - Jun 22

Premium bedding, down comforters, in-room safe, desk

Omni Viking Lakes Hotel

Eagan

₩281,899 total

includes taxes & fees

Jun 28 - Jun 29

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Top Southern Minnesota Hotel Reviews

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

8/10 Good

"The restaurant I’d first rate. The provided transportation to and from Mayo and surrounding area was first rate. The colonial breakfast was good. The staff support was first rate. The price was a good value. The condition of the hotel was just ok."

Kahler Grand Hotel

2/10 Terrible

"I usually stay at another hotel for my Mayo Clinic appointments and treatment but it was full so I booked at Kaylee Grand due to convenience. When I checked in, all seemed fine until we got to our room. The state of the bathroom was disgusting! Massive amounts of hair on the floor and in the bathtub. We let the front desk know as we were heading to appointments. 4 hours later the room was not cleaned and when we took our concerns to the front desk they were totally dismissed. We asked to speak to management and were told they were unavailable, which was a lie. For someone in cancer treatment at the Mayo Clinic, this is totally unacceptable. People need to see this feedback!!"

Med City Inn & Suites - Mayo Clinic Area

4/10 Poor

"The pool was really dirty. On the side of the side of the pool, you could see people scratching their initials in it through the scum. I was on the first floor and the carpet was damp because of all the condensation while it was really warm or it was leaking or something. The beds weren’t comfortable. The breakfast waffle maker did not work. Although it was not ideal for the cost, I guess you get what you pay for."