Photo by Visit Greenville, South Carolina

Greenville 5 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Greenville 5 Star Hotels

Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Greenville.
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

44 EAST CAMPERDOWN WAY Greenville SC
The price is ₩471,389 per night from Jan 4 to Jan 5
₩471,389
₩532,669 total
Jan 4 - Jan 5, 2026
includes taxes & fees
9.4/10 Exceptional! (418 reviews)
Still don't see what you're looking for?
See all properties in Greenville.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Greenville

Falls Park on the Reedy offers a stunning urban oasis with waterfalls right in the heart of downtown. Bike the Swamp Rabbit Trail in the morning, then explore Main Street's locally-owned shops and farm-to-table restaurants by afternoon.

See all hotels in Greenville
Greenville which includes a river or creek, a city and a bridge
Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Top Greenville Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Greenville?
The amount you pay for a 5-star hotel in Greenville can vary depending on what time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to find the best deal on a plush stay.

  • Search for the lowest price per night from ₩274,706

What makes a hotel 5 stars in Greenville?
Faultless guest service is the defining feature of every 5-star hotel in Greenville. From the minute you arrive, staff are at your beck and call, whether arranging customized tours or providing a turn-down service. Also, hotels must feature upscale amenities to qualify for a 5-star rating. These can include luxury bathrobes, spas or saunas, pools, gourmet kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Greenville?
Find a luxury retreat that includes your room, meals, drinks and entertainment in Greenville with our filters. Search for resorts with a 5-star rating and select the "All inclusive" filter. Have a look at what's included in the purchase price. This way, you're ready to take advantage of all the premium perks from the moment you get there.

Explore a world of travel with Expedia