Alexander County Vacations & Trips

Book a Hotel + Flight or Car together to unlock savings

Photo by Jen - Nealys On Wheels

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩1,660,000 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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    Plan, book, and manage your trip all in one place

Alexander County Hotel Deals

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ₩156,531 per night from Jul 6 to Jul 7
₩156,531
₩176,589 total
Jul 6 - Jul 7
includes taxes & fees
9.6/10 Exceptional! (1,008 reviews)
"Right off the hwy very nice"

Reviewed on Jun 28, 2026

Drury Plaza Hotel Cape Girardeau Conference Center
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
The price is ₩170,344 per night from Jul 12 to Jul 13
₩170,344
₩195,854 total
Jul 12 - Jul 13
includes taxes & fees
9.6/10 Exceptional! (1,004 reviews)
"Quick check-in. Room was very clean and nice. Staff was helpful. Would definitely stay here again."

Reviewed on Jun 28, 2026

Drury Inn & Suites Sikeston, MO
The Riverview

The Riverview

4 out of 5
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is ₩203,050 per night from Jun 29 to Jun 30
₩203,050
₩229,068 total
Jun 29 - Jun 30
includes taxes & fees
9.4/10 Exceptional! (613 reviews)
"The view of the river from the 3rd floor.Starbucks downstairs.Big open room and bathroom."

Reviewed on Jun 28, 2026

The Riverview
See all 220 properties in Alexander County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Alexander County vacation package cost?
Maybe less than you might think — from as low as , actually! By combining hotels, flights and car rentals into your own tailor-made vacation package, your getaway to Alexander County is only clicks away.
How do I get a cheap travel package to Alexander County?
Our Alexander County vacation packages promise plenty of savings for the savvy wanderer. For the best deal, simply combine your flights, hotels and rental cars into a convenient package. But great bargains are just the beginning of your next unforgettable adventure. When you book with Expedia, you'll have more than 550 airlines and 1,000,000 hotel options globally to select from. Whatever your style or budget, there's a vacation package here just for you.
What are the top hotels in Alexander County?
If you're headed to Tamms, you can't go wrong with Quality Inn Cairo I-57 and Beautiful Cabin Retreat. Both are great bases for discovering this unique Alexander County city.
How far in advance should I book my Alexander County vacation?
Reserving your flights early with Expedia means one less thing to worry about. Many air carriers advertise prices up to 12 months prior to departure dates. Typically, this is the cheapest time to book. If circumstances have left you booking late, incredible deals to Alexander County sometimes emerge just a few weeks before departure.
What does an Expedia Alexander County travel package include?
Flights, hotels and a cool car for all your road trip adventures. Simply choose your favorite bundle and gain access to great discounts. Once you've made your booking, add on some tours and experiences and watch your savings grow. When it comes to creating your Alexander County getaway, you're in control!
What should I know before booking an Alexander County travel package?
Get set to save with an Expedia travel package. Combine your airfares, rental cars and hotels and score fabulous discounts. You're not limited to hotels, however. Book with us and choose from beachfront villas, chalets in the middle of mountains and even houseboats and castles!
Can I choose my airline with an Alexander County Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our vacation packages give you the flexibility to take your pick of available flights, hotels and activities that suit you.
If I'm not able to travel, can I cancel my Alexander County vacation package?
You can. We totally understand that life happens, so we're happy to help if you have to make changes to your Alexander County vacation package. You may be able to cancel or change your itinerary for free if you've booked within 24 hours. Your hotel, airline or car rental company may impose a fee if you booked more than 24 hours ago. Take a look at our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.

Stay near popular Alexander County attractions

Fort Defiance State Park

7.4/5 (15 reviews)
You can take time to visit Fort Defiance State Park during your travels to Cairo. Stroll along the riverfront or visit the churches while you're in the area.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.