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Our top choices for Byron hotels

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Residence Inn by Marriott Rochester Mayo Clinic Area

Residence Inn by Marriott Rochester Mayo Clinic Area
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (201 reviews)
"We were there for 3 nights while visiting Doctors at Mayo. The location is very good and is connected to the Mayo Subway. The hotel was clean and staff friendly. "
United States
James
The price is ₩219,712
₩252,949 total
includes taxes & fees
Jan 31 - Feb 1
Residence Inn by Marriott Rochester Mayo Clinic Area
Exterior

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park
9.2 out of 10, Wonderful, (777 reviews)
"Staff was very helpful and positive. "
United States
Bradley
The price is ₩138,611
₩159,576 total
includes taxes & fees
Jan 31 - Feb 1
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Front of property - evening/night

The Towers At Kahler Grand Hotel

The Towers At Kahler Grand Hotel
4.0 star property
Downtown Rochester
9.4 out of 10, Exceptional, (96 reviews)
  • cleanliness
    Located near Mayo Clinic with indoor pool and Lord Essex restaurant on-site.
"Excellent accommodations, amazing staff"
United States
Shannon
The price is ₩642,912
₩740,152 total
includes taxes & fees
Jan 27 - Jan 28
The Towers At Kahler Grand Hotel
2 indoor pools

TownePlace Suites by Marriott Rochester

TownePlace Suites by Marriott Rochester
3.0 star property
Rochester
8.8 out of 10, Excellent, (544 reviews)
"My kids really enjoyed the pool, and so did I! Room was nice & clean. Staff were nice. I really appreciated the late checkout. (At least compared to other hotels, 12pm is late!) "
United States
Ashley
The price is ₩144,509
₩166,367 total
includes taxes & fees
Jan 29 - Jan 30
TownePlace Suites by Marriott Rochester
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (169 reviews)
  • cleanliness
    Convenient Mayo Clinic access with pool, hot tub, and apartment-style amenities.
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is ₩237,555
₩273,505 total
includes taxes & fees
Jan 24 - Jan 25
Broadway Plaza, Trademark Collection by Wyndham
Exterior

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park
8.8 out of 10, Excellent, (772 reviews)
  • cleanliness
    Stay close to Mayo Clinic in Rochester with free breakfast and parking.
"the staff was friendly and helpful/ and the room was clean/ and good amenities"
United States
carol
The price is ₩152,535
₩175,606 total
includes taxes & fees
Feb 8 - Feb 9
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
View from property

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park
9.6 out of 10, Exceptional, (685 reviews)
  • cleanliness
    A comfortable stay near Mayo Clinic with convenient shuttle service and amenities.
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is ₩144,509
₩166,366 total
includes taxes & fees
Feb 20 - Feb 21
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Terrace/patio

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (903 reviews)
  • cleanliness
    Modern suites with indoor pools just 5 minutes from Mayo Clinic facilities.
"Staff, room and breakfast were wonderful!"
United States
DeLaine
The price is ₩180,164
₩207,414 total
includes taxes & fees
Jan 29 - Jan 30
Home2 Suites by Hilton Rochester Mayo Clinic Area
Lobby lounge

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
Kutzky Park
8.6 out of 10, Excellent, (956 reviews)
"Friendly staff, good breakfast."
United States
Missy
The price is ₩138,611
₩159,577 total
includes taxes & fees
Jan 31 - Feb 1
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Lobby

Red Carpet Inn Rochester

Red Carpet Inn Rochester
2.0 star property
Rochester
7.6 out of 10, Good, (535 reviews)
  • cleanliness
    Convenient hotel near Mayo Clinic with free parking and housekeeping service.
"Quiet and affordable. Comfortable beds."
United States
Amy
Red Carpet Inn Rochester
Free daily full breakfast

Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (841 reviews)
  • cleanliness
    Enjoy a peaceful stay near Mayo Clinic with convenient access to Rochester attractions.
"Great stay!"
United States
William
The price is ₩97,370
₩113,696 total
includes taxes & fees
Feb 15 - Feb 16
Quality Inn & Suites Mayo Clinic Area
Property entrance

Country Inn & Suites Rochester South Mayo Clinic

Country Inn & Suites Rochester South Mayo Clinic
3.0 star property
Rochester
8.4 out of 10, Very Good, (1,003 reviews)
  • cleanliness
    Contemporary hotel near Mayo Clinic offers comfort with indoor pool and hot tub.
"Rooms are always clean wonderful service from the staff. It’s a great place to stay."
United States
Jamie
The price is ₩128,396
₩147,816 total
includes taxes & fees
Feb 15 - Feb 16
Country Inn & Suites Rochester South Mayo Clinic
City view from property

Marriott Rochester Mayo Clinic

Marriott Rochester Mayo Clinic
3.5 star property
Downtown Rochester
8.4 out of 10, Very Good, (529 reviews)
  • cleanliness
    Perfectly located minutes from Mayo Clinic, this hotel offers pool and dining options.
"it was a fantastic "
United States
Paul
The price is ₩249,204
₩286,896 total
includes taxes & fees
Jan 31 - Feb 1
Marriott Rochester Mayo Clinic
Pub

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (489 reviews)
  • cleanliness
    Contemporary hotel near Mayo Clinic with free breakfast and area shuttle service.
"Staff was very helpful. Room was spacious and beds were very comfortable. "
United States
Lisa
The price is ₩187,272
₩215,597 total
includes taxes & fees
Feb 21 - Feb 22
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Restaurant

Hampton Inn & Suites Rochester-North

Hampton Inn & Suites Rochester-North
2.5 star property
Rochester
9.2 out of 10, Wonderful, (1,000 reviews)
  • cleanliness
    Explore Mayo Clinic then unwind in this modern Rochester hotel's heated pool.
"Will stay again."
United States
dennis
The price is ₩131,798
₩151,732 total
includes taxes & fees
Feb 1 - Feb 2
Hampton Inn & Suites Rochester-North
Breakfast served

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester
8.8 out of 10, Excellent, (866 reviews)
  • cleanliness
    Convenient downtown Rochester lodging, minutes from Mayo Clinic.
"Very convenient and clean hotel "
United States
Kirsten
The price is ₩157,824
₩181,694 total
includes taxes & fees
Jan 31 - Feb 1
Hilton Garden Inn Rochester Downtown, MN
Exterior

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Experience comfort near Rochester International Airport with a complimentary shuttle.
"Enjoyed our stay, rated breakfast as a erage as we did not try it."
United States
jeanne
The price is ₩112,032
₩128,976 total
includes taxes & fees
Feb 19 - Feb 20
Comfort Inn & Suites Rochester South Mayo Clinic
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (917 reviews)
  • cleanliness
    Peaceful stay near Mayo Clinic, featuring rooftop terrace and fitness center.
"Great stay as always! "
United States
Misty
The price is ₩137,136
₩157,877 total
includes taxes & fees
Jan 24 - Jan 25
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Indoor pool

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
Rochester
9.6 out of 10, Exceptional, (261 reviews)
  • cleanliness
    Relax near Mayo Clinic with a hot tub and modern fitness center at your disposal.
"Staff was great and helpful, lovely room!, quiet area, restaurants nearby"
United States
Ann Marie
The price is ₩194,645
₩224,085 total
includes taxes & fees
Jan 31 - Feb 1
Residence Inn by Marriott Rochester Mayo Clinic Area South
Lobby

Sleep Inn & Suites West-Near Medical Center

Sleep Inn & Suites West-Near Medical Center
2.5 star property
Rochester
9.0 out of 10, Wonderful, (590 reviews)
  • cleanliness
    Convenient access to Mayo Clinic, with indoor pool and free breakfast for travelers.
"Nice place to stay "
United States
Melissa
The price is ₩127,846
₩147,183 total
includes taxes & fees
Feb 21 - Feb 22
Sleep Inn & Suites West-Near Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Byron attractions

Putting Green

Enjoy a round of golf in Byron at Putting Green. Amble around the area's parks or experience its art scene.
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Oxbow Park

Explore the great outdoors at Oxbow Park, a lovely green space in Byron. Check out the charming coffeehouses or top-notch restaurants in this walkable area.
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Top Byron Hotel Reviews

The Berkman

The Berkman

10/10 Excellent
"This is a wonderful, comfortable space. My mom was hospitalized at St. Mary’s and I was able to run back over within 5 minutes when I needed to. It was so nice to have a cozy welcoming space during the chaos of having someone hospitalized. "
April 1-night trip
Posted 22 hours ago
The Berkman

More cheap stays in Byron

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

4210 Highway 52 North Rochester MN
The price is ₩95,258 per night from Jan 30 to Jan 31
₩95,258
₩109,666 total
Jan 30 - Jan 31
includes taxes & fees
7.8/10 Good! (1,002 reviews)

Frequently asked questions

Where is the best place to stay in Byron?
Located 9 mi (14.4 km) from the heart of Byron, Kahler Grand Hotel is a top choice for your stay based on our traveler data. Other good choices for your visit to the area are Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG. See all available top hotels, or vacation rentals in Byron.
If I need to cancel my hotel reservation in Byron, will I receive a refund?
Yes! Most hotel room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Byron.
Where can I learn more about changing or cancelling my trip to Byron?
To find more details about updating your trip to Byron or cancelling it, head over to our customer service page.
Where is the best place to stay near Oxbow Park?
Staybridge Suites Rochester - Commerce Dr NW, an IHG Hotel is one of the top choices for your stay based on our traveler data, and this 3-star hotel offers free breakfast and an indoor pool. You'll find it 7 mi (11.3 km) from Oxbow Park. Other good choices around the area include Baymont by Wyndham Kasson Rochester Area and Hampton Inn & Suites Rochester-North.
How is it to stay in Byron?
Visitors can enjoy all that Byron has to offer including the zoo, golf courses, and bars. Tourists can also enjoy the city's parks and art. In Byron, there are 2 hotels and other accommodations to choose from. Find out more about Byron.
What should I see while I'm in Byron?
Favorite places to visit include Putting Green, Links of Byron Mini Golf, and Cheery Meadows Center. A couple of additional sights to add to your agenda are High Point Shopping Center and Byron Town Square. Check out what more to see and do in Expedia's Byron guide.
What's the weather like in Byron?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 21°F. The snowiest months in Byron are January, March, April, and February, with each month seeing an average of 8 inches of snowfall.

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