East Seneca Vacations

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Where to stay in East Seneca

Find the best East Seneca areas and neighborhoods for the activities you enjoy most. Learn more about East Seneca
Buffalo showing a city, a monument and a skyscraper

Downtown Buffalo

4 out of top 10 points of interest in this area
4/5(1,204 area reviews)

Experience the city's rich culture with visits to the oldest urban parks system in the US, Albright–Knox Art Gallery, and Shea's Performing Arts Center. Enjoy annual festivals and explore nearby universities.

Find hotels in Downtown Buffalo

East Seneca Hotel Deals

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is ₩136,983 per night from Sep 1 to Sep 2
₩136,983
₩155,824 total
Sep 1 - Sep 2
includes taxes & fees
M Hotel Buffalo
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is ₩153,139 per night from Sep 2 to Sep 3
₩153,139
₩174,181 total
Sep 2 - Sep 3
includes taxes & fees
7.8/10 Good! (2,538 reviews)
"Good"

Reviewed on Aug 27, 2025

Buffalo Airport Hotel
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
The price is ₩175,330 per night from Sep 1 to Sep 2
₩175,330
₩199,440 total
Sep 1 - Sep 2
includes taxes & fees
7.8/10 Good! (1,432 reviews)
"Good place"

Reviewed on Aug 28, 2025

Hyatt Regency Buffalo / Hotel and Conference Center
See all 762 properties in East Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an East Seneca vacation package cost?
Get set to book, because a trip to East Seneca starts from an enticing . When you bundle your hotels, flights and car rentals into a vacation package, you'll enjoy the biggest bargains.
How do I get a cheap travel package to East Seneca?
Combine your hotels and flights, add on extras such as activities or a rental car, and save with an East Seneca vacation package. You won't just score exciting discounts on your escape — you'll have loads of choice at your fingertips too. When you book with Expedia, you'll have your pick of over 550 air carriers and 1,000,000 properties worldwide. Your next big adventure starts right here, right now!
Where should I stay in East Seneca?
With popular attractions like Southgate Plaza and Charles E. Burchfield Nature and Art Center in this neighborhood, look for a hotel situated near either of them. Enjoy The Journey Art Gallery is another East Seneca sight that visitors flock to.
How far in advance should I book my East Seneca vacation?
While prices fluctuate, we generally recommend booking your flight as soon as possible. Most international airfares can be compared on Expedia up to a year in advance. If circumstances have left you booking late, you might still get lucky. Cheap tickets to East Seneca sometimes occur just weeks before departure.
What does an Expedia East Seneca travel package include?
Much of that depends on you. You can choose from a variety of East Seneca packages, such as a hotel, rental car and flight. You can also book a hotel with a flight, or a rental car and a flight. Once you've made your booking, you can add on the fun stuff like experiences and tours. Whatever your ideal East Seneca trip looks like, get ready to save!
What should I know before booking an East Seneca travel package?
You'll save big with an Expedia travel package. Bundle your airfares, rental cars and hotels and unlock terrific discounts. Hotels aren't your only option, though. We have island villas, mountain cabins and even glamping tents!
Can I choose my airline with an East Seneca Expedia vacation package?
Expedia offers access to more than 550 airline partners worldwide, so you certainly can. Just pick your preferred air carrier and create the perfect East Seneca trip.
If I'm not able to travel, can I cancel my East Seneca vacation package?
Whether it's your flight or hotel, yes, you can cancel or amend it. Booked your East Seneca vacation package in the last 24 hours? You may be able to make changes or cancellations for free. For bookings made more than 24 hours ago, you may be charged a fee by your hotel, airline or car rental company. For further information, check out our Customer Service Portal. We're here to help you each step of the way.

Discover the most popular places to visit in East Seneca

Buffalo General Medical Center

Though Buffalo General Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Buffalo while you are here.

Buffalo General Medical Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.