A red truck parked near a tent in a desert at night with stars visible in the sky.

Find Luxury Hotels in Eastern Oregon, OR

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
  • Be picky

    Search almost a million properties worldwide

Check availability on Eastern Oregon Luxury Hotels

Tonight
Oct 25 - Oct 26
Tomorrow
Oct 26 - Oct 27
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Eastern Oregon luxury hotels

1. Cameo Heights Mansion

Cameo Heights Mansion
Touchet
  • Unwind at a countryside mansion with a full-service spa, outdoor pool, and sophisticated dining in the Walla Walla Valley region.
₩385,350
₩461,534 total
includes taxes & fees
Nov 1 - Nov 2
Cameo Heights Mansion
View all properties

Top Eastern Oregon Hotel Reviews

Motel 6 Pendleton, OR

Motel 6 Pendleton, OR

8/10 Good
"Clean room, friendly staff, parking right up to our room entrance, and quiet. It was a win I'd say. Coffee to go at departure was added bonus. For the price, I'd stay here again."
HEATHER 1-night trip
Posted 12 hours ago
Motel 6 Pendleton, OR
Oxford Suites Hermiston

Oxford Suites Hermiston

10/10 Excellent
"Amazing stay. The only issue was the elevator was not working. We did not mind taking the stairs but some else may have an issue using the stair. Will stay there again"
Lorrie 2-night trip
Posted 15 hours ago
Oxford Suites Hermiston

Explore a world of travel with Expedia