Find hotels in Ensanche Isabelita, Santo Domingo

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Ensanche Isabelita hotels

Bright and Youth Condo With hot Water

Bright and Youth Condo With hot Water
2.5 star property
Ensanche Isabelita
The price is ₩45,795
₩73,292 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Bright and Youth Condo With hot Water

La Vita E' Bella Hotel Ristorante

La Vita E' Bella Hotel Ristorante
3.5 star property
Ensanche Isabelita
8.4 out of 10, Very Good, (117)
"Spotless room and friendly staff. "
United States
Jefferson
La Vita E' Bella Hotel Ristorante

Acuarium Suite Resort

Acuarium Suite Resort
2.5 star property
Ensanche Isabelita
6.8 out of 10, (372)
"everything was excellent "
United States
Luis
The price is ₩72,722
₩93,084 total
includes taxes & fees
Dec 29 - Dec 30
Acuarium Suite Resort

Setup Hotels

Setup Hotels
3.0 star property
Ensanche Isabelita
6.6 out of 10, (99)
"Staff is great close to everything the girls work hard to accommodate "
United States
Alejandro
The price is ₩35,090
₩67,610 total
includes taxes & fees
Dec 24 - Dec 25
Setup Hotels

Hotel Bellamar

Hotel Bellamar
2.0 star property
Ensanche Isabelita
3.6 out of 10, (5)
"There is no front desk! And there’s no one there to check me in. I never stayed at the hotel because I could not get access. The area is also shady… party area and felt a bit unsafe to walk the street. I ended up sleeping in my car…Very disappointing!"
Canada
Niki
The price is ₩46,541
₩54,918 total
includes taxes & fees
Dec 25 - Dec 26
Hotel Bellamar

Safe and Economical, for a Long Time

Safe and Economical, for a Long Time
3.0 star property
Ensanche Isabelita
The price is ₩48,754
₩76,783 total
includes taxes & fees
Dec 29 - Dec 30
Safe and Economical, for a Long Time

Casas del XVI

Casas del XVI
5.0 star property
5.3 km from Ensanche Isabelita
9.4 out of 10, Exceptional, (230)
"Everything was amazing "
United States
Lesterlin
The price is ₩416,270
₩532,825 total
includes taxes & fees
Dec 24 - Dec 25
Casas del XVI

Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial
3.5 star property
4.7 km from Ensanche Isabelita
8.8 out of 10, Excellent, (256)
"Amazing services on our stay. "
United States
Gilbert
The price is ₩131,497
₩168,316 total
includes taxes & fees
Dec 30 - Dec 31
Mosquito Boutique Hotel Zona Colonial

Luca Hotel by Heritage Residences Signature Collection

Luca Hotel by Heritage Residences Signature Collection
3.5 star property
4.8 km from Ensanche Isabelita
9.2 out of 10, Wonderful, (702)
"Great staff, clean and comfortable An rooms"
United States
Asfaha
Luca Hotel by Heritage Residences Signature Collection

CALYPSO BEACH HOTEL

CALYPSO BEACH HOTEL
3.0 star property
24.9 km from Ensanche Isabelita
7.2 out of 10, Good, (7)
"Excellent service and very affordable the staff very friendly!!!"
United States
Jaime
The price is ₩47,105
₩67,788 total
includes taxes & fees
Dec 24 - Dec 25
CALYPSO BEACH HOTEL

Boca Beach Residence

Boca Beach Residence
3.5 star property
24.2 km from Ensanche Isabelita
7.6 out of 10, Good, (477)
"Enjoyed "
United States
Richard
The price is ₩115,436
₩147,749 total
includes taxes & fees
Dec 27 - Dec 28
Boca Beach Residence

Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR

Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR
4.0 star property
5.1 km from Ensanche Isabelita
10.0 out of 10, Exceptional, (1)
"Clean, quite with someone at front dest 24/7. Santa Dominga is not the typicalspot but a great sovacation "
United States
Charles
The price is ₩309,963
₩365,757 total
includes taxes & fees
Dec 25 - Dec 26
Boutique Hotel Casa Grande, Dominican Voyage Familiar Suite, 2 BR

Hotel Garant & Suites

Hotel Garant & Suites
3.0 star property
24.7 km from Ensanche Isabelita
8.6 out of 10, Excellent, (503)
"Staff very friendly and helpful "
United States
maria claribel
The price is ₩62,232
₩92,895 total
includes taxes & fees
Dec 24 - Dec 25
Hotel Garant & Suites

Billini Hotel, Historic Luxury

Billini Hotel, Historic Luxury
4.5 star property
4.9 km from Ensanche Isabelita
9.2 out of 10, Wonderful, (806)
"Great "
United States
Steven
The price is ₩305,840
₩391,475 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Billini Hotel, Historic Luxury

El Beaterio

El Beaterio
3.0 star property
4.7 km from Ensanche Isabelita
9.2 out of 10, Wonderful, (422)
"Clean, comfortable, quiet room in a charmimg 16th century Beaterio located perfectly in the Colonial Zone. The staff was very accommodating and the breakfast good. Will stay again."
United States
leslie
The price is ₩150,054
₩192,069 total
includes taxes & fees
Jan 4 - Jan 5, 2026
El Beaterio

Hotel Refugio Neptuno's

Hotel Refugio Neptuno's
3.0 star property
25.2 km from Ensanche Isabelita
7.8 out of 10, Good, (328)
"Room was clean and comfortable, staff friendly, breakfast surprisingly good."
United Kingdom
Anthony
The price is ₩80,538
₩103,084 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Hotel Refugio Neptuno's

Napolitano Hotel

Napolitano Hotel
3.0 star property
5.3 km from Ensanche Isabelita
7.6 out of 10, Good, (880)
"Room was clean, staff polite and the best part was the Terrace /Pool/ Bar!! My family really enjoyed. Waitress did an extraordinary service, specially Ms. Iris. "
United States
Maria
Napolitano Hotel

Crowne Plaza Santo Domingo by IHG

Crowne Plaza Santo Domingo by IHG
5.0 star property
5.9 km from Ensanche Isabelita
8.8 out of 10, Excellent, (1000)
"Beautiful view, friendly staff, great breakfast! "
United States
prana
The price is ₩216,090
₩276,595 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Crowne Plaza Santo Domingo by IHG

Plaza Florida Suites

Plaza Florida Suites
3.0 star property
8.9 km from Ensanche Isabelita
9.0 out of 10, Wonderful, (302)
"Excellent staff and service"
United States
Christian
The price is ₩127,330
₩150,246 total
includes taxes & fees
Dec 27 - Dec 28
Plaza Florida Suites

Batey Hotel Boutique

Batey Hotel Boutique
3.5 star property
24.8 km from Ensanche Isabelita
8.2 out of 10, Very Good, (577)
"Great location and staff.Rooms are clean, Food and Drinks is great!"
United States
Roydell
The price is ₩79,784
₩102,123 total
includes taxes & fees
Dec 24 - Dec 25
Batey Hotel Boutique
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Ensanche Isabelita

Find the best Ensanche Isabelita areas and neighborhoods for the activities you enjoy most.

Zona Colonial

Zona Colonial is known for its ample dining options, and you can make a stop by Calle El Conde and Santa Maria la Menor Cathedral while in the area.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Downtown Santo Domingo

Polígono Central boasts a mix of commercial and residential zones, with a high concentration of malls, banks, and international fast food chains. Enjoy daily sports activities at Club Paraiso and Club Naco, or explore the city via Santo Domingo Metro and OMSA bus system.

Ciudad Colonial

Discover the historic heart of Santo Domingo, where cobblestone streets like Calle Las Damas lead to landmarks such as Alcázar de Colón and Catedral de Santa María la Menor. Stroll along pedestrian-only Calle del Conde, and enjoy local shops and restaurants near Plaza de España.

Bella Vista

When in Bella Vista, you can plan a visit to Acropolis Center and Bella Vista Mall, some noteworthy sights in the nearby area.

Top Ensanche Isabelita Hotel Reviews

Frequently asked questions

What is Ensanche Isabelita like?
Travelers are sure to enjoy a stay in Santo Domingo Este's Ensanche Isabelita neighborhood.
Where is the best place to stay in Ensanche Isabelita?
Based on Expedia customer reviews, La Vita E' Bella Hotel Ristorante is the highest ranked property in Ensanche Isabelita. This hotel offers free breakfast and an outdoor pool.
How many hotels will I find in the Ensanche Isabelita area?
Expedia has 36 hotels and other accommodations in Ensanche Isabelita to choose from, making this an ideal home base for exploring the greater Santo Domingo Este area.
If I need to cancel my hotel reservation in Ensanche Isabelita, will I receive a refund?
Yes, you'll find most hotel reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best deals in Ensanche Isabelita.
Where can I learn more about changing or cancelling my trip to Ensanche Isabelita?
To access more information about picking new dates or cancelling your trip to Ensanche Isabelita, click here.
What can I see and do in this Santo Domingo Este neighborhood?
Three Eyes National Park, National Aquarium, and Agua Splash Caribe Aquatic Park are just a few of the places to visit in and around Ensanche Isabelita. Agua Splash Caribe Parque Acuatico and Assembly Hall of Jehovah's Witnesses are also worth a visit when you're out sightseeing in Santo Domingo Este.