Top Epipoli Hotels

An ancient amphitheater with stone seating and a small tower.

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Where to stay in Epipoli

Find the best Epipoli areas and neighborhoods for the activities you enjoy most.

A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

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A modern building with a unique triangular roof and a central spire.

Santa Lucia

Santa Lucia is noteworthy for its historic sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

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A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

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Ancient ruins with a large amphitheater surrounded by trees.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

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An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

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Top Epipoli Hotel Reviews

Maniace Boutique Hotel Ortigia UNA Esperienze

10/10 Excellent

"We arrived feeling stressed after the drive to the hotel! The lovely young lady on the front desk welcomed us with a warm Smile and arranged for the bartender to bring us a drink outside so we could soak up the afternoon sun and relax. We were served a delicious aperol. The decor throughout the hotel is very tasteful even the corridors to the room. Clean white walls but a hint of original brickwork showing. Comfy beds, crisp white linen. Lovely toiletries in the bathroom. Everywhere was spotless. Great breakfast and amazing service. Lovely location just opposite the pretty pebbly beach and around the corner from the lovely streets full of restaurants, shops and wonderful architecture. Would definitely return."

Lanterne Magiche Ortigia

10/10 Excellent

"I was so impressed with how spacious, clean and comfortable the rooms were, not to mention the amazing location. Staff were warm, welcoming and so helpful. I kept adding more days to my stay because I truly loved it here and felt so relaxed and at home. I will definitely be back in the future!"

Grand Hotel Villa Politi

8/10 Good

"We overall really enjoyed our 3 night stay here, and appreciated the quiet and historic charm of this hotel. It is an incredibly unique peace of property, with an attached historic Latomie that was both beautiful and intriguing—we really wished the hotel had access to explore the areas below. We also really appreciated the continental breakfast, and were surprised by other’s complaints in reviews we had read before staying here. It was the most elaborate continental breakfast we have ever experienced, with options ranging from fresh fruit, to delicious pastries, and even eggs and bacon for those with used to a more American meal. We loved the pool as well, however we were disappointed that it was only open until 7pm every day, we would have enjoyed an evening swim. The bar was also closed, though they provided service through the bar inside. We also really enjoyed the 2 for $22 aperitivo offered from the bar. The room we stayed in was small and a bit dated, but met our expectations for an older hotel. We also had issues with the AC not turning off and making our room very cold. We were able to find parking every night, however I would not describe it as a big parking lot, and it was overflowing every night with people crammed wherever they could find room."

Domus Mariae Albergo

10/10 Excellent

"Property is well located and staff was really helpful. If going in a rental, make sure you call ahead of time to register the car with the city and have a parking spot in one of the nearby garages. Parking is definitely scarce in Ortigia. The images from the hotel show a gym, that is a bit misleading."

Algila' Ortigia Charme Hotel

10/10 Excellent

"Beautiful hotel with wonderful hospitality We absolutely loved our stay at Hotel Algilà Ortigia Charme. From the moment we arrived, the staff were warm, friendly and genuinely welcoming. The hotel is full of Sicilian character and charm, and its location in Ortigia was perfect for exploring on foot. Our room was comfortable and beautifully suited to the character of the hotel, and the staff were always happy to help with recommendations and anything we needed. After travelling throughout Sicily for two weeks, what stood out most was the genuine hospitality. We felt like valued guests, not just another reservation. Algilà was exactly what we hoped for from a Sicilian hotel — charming, personal and welcoming. We would happily stay here again and highly recommend it to anyone visiting Ortigia!"

Frequently asked questions

What is Epipoli like?

Travelers to the Epipoli neighborhood in Syracuse will be sure to enjoy their stay.

What's the best accommodation in Epipoli?

Based on our traveler data, Hotel Relax is one of the top choices for your stay in Epipoli. This hotel offers a full-service spa and a restaurant.

How many hotels will I be able to find in the Epipoli area?

When you want to find places to stay in Syracuse, start by booking one of Expedia's 7 hotels and other accommodations in Epipoli.

If I need to cancel my hotel reservation in Epipoli, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Epipoli.

Where can I learn more about changing or cancelling my trip to Epipoli?

To find more details about changing or cancelling your trip to Epipoli, head over to our customer service page.

What can I see and do in this Syracuse neighborhood?

A few places to visit in the area around Epipoli include Cantine Pupillo, Greek Theatre of Syracuse, and Latomia del Paradiso. Rope-makers' Cave and Ear of Dionysius are also worth a visit when you're out sightseeing in Syracuse.

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Our top choices for Epipoli hotels

1. B&B Kosmos

2. Hotel Relax

3. Algila' Ortigia Charme Hotel

4. Hotel Parco delle Fontane

5. Maniace Boutique Hotel Ortigia UNA Esperienze

6. Grand Hotel Villa Politi

7. Mercure Siracusa Prometeo

8. Grande Albergo Alfeo

9. UNA Hotels One Siracusa Wellness & SPA

10. Grand Hotel Ortigia Siracusa

11. Charme Hotel Henry's House

12. Caportigia Boutique Hotel

13. EGEO - Ortigia

14. Ortea Palace Hotel, Sicily, Autograph Collection

15. Maecò Ortigia B&B

16. Grand Hotel Des Ètrangers - The Leading Hotels of the World

17. Palazzo Artemide - VRetreats, SLH Collection

18. Nostos rooms & Apartments

19. CinqueSuites Ortigia

20. Hotel Palazzo Cavalieri

Where to stay in Epipoli

Ortigia

Santa Lucia

Grottasanta

Neapolis

Tiche

Top Epipoli Hotel Reviews

Maniace Boutique Hotel Ortigia UNA Esperienze

Frequently asked questions

Explore a world of travel with Expedia