A calm lake surrounded by trees with autumn foliage.

Find Pet-friendly Hotels in Florence, SC

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November 2026

December 2026

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Our top choices for Florence pet-friendly hotels

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

1. Park Inn by Radisson Florence, SC

Florence

Susan

₩135,764 total

includes taxes & fees

Nov 15 - Nov 16

A hotel lobby with a reception desk, seating area, and a television screen.

2. Comfort Inn & Suites Florence Center Area

Florence

Jana

₩152,163 total

includes taxes & fees

Dec 1 - Dec 2

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

3. Hampton Inn & Suites Florence-North-I-95

Florence

chantal

₩171,344 total

includes taxes & fees

Nov 19 - Nov 20

A hotel entrance with a covered walkway, a brick pathway, and a well-maintained garden.

4. Staybridge Suites Florence - Civic Center by IHG

Florence

Zachary

₩183,529 total

includes taxes & fees

Dec 6 - Dec 7

A hotel room with a desk, a bed, a sofa, a TV, and a mirror.

5. Quality Inn & Suites Florence Civic Center

Florence

Franklin

₩134,036 total

includes taxes & fees

Nov 25 - Nov 26

A spacious lobby with a reception desk, seating area, and large windows.

6. Hilton Garden Inn Florence

Florence

Maria

₩171,342 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with wicker furniture, a wooden pergola, and a barbecue setup.

7. Homewood Suites by Hilton Florence

Florence

Delita

₩152,674 total

includes taxes & fees

Nov 22 - Nov 23

8. Home2 Suites by Hilton Florence, SC

Florence

Emily

₩179,434 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

9. TownePlace Suites by Marriott Florence

Florence

Ralph

₩164,950 total

includes taxes & fees

Nov 16 - Nov 17

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

10. Comfort Suites Florence I-95

Florence

Michael

₩178,315 total

includes taxes & fees

Dec 7 - Dec 8

View all properties

Top Florence Hotel Reviews

A two-story house with a wrap-around porch, brick exterior, and a front entrance with steps.

1912 Bed and Breakfast

Sumter

10/10 Excellent

Sherise L.

Staybridge Suites Florence - Civic Center by IHG

Florence

10/10 Excellent

William

An outdoor patio area with a fire pit, seating, and a covered section with a grill.

TownePlace Suites by Marriott Sumter

Sumter

10/10 Excellent

Shalaqua

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

Hampton Inn & Suites Florence Center

Florence

10/10 Excellent

Shawn

Hampton Inn & Suites Florence-North-I-95

Florence

10/10 Excellent

I chose Hampton Inn in Florence because, overall, in the past I have had excellent experiences with this chain. I was very pleasantly treated to a very beautifully appointed hotel setting, it was also very clean. I saw staff picking up small items or pieces of paper that had been left or dropped by a visitor. My room itself was very clean and the bed was very comfortable and the room had it's own thermostat so the temperature and whether you wished heat or air could be selected for...

Anonymous traveler

Comfort Inn & Suites Florence Center Area

Florence

10/10 Excellent

Roland

Park Inn by Radisson Florence, SC

Florence

10/10 Excellent

Nichole

A spacious restaurant with high ceilings, hanging crystal chandeliers, and a variety of seating options including tables and booths.

Hampton Inn & Suites Hartsville

Hartsville

10/10 Excellent

Sean

TownePlace Suites by Marriott Florence

Florence

10/10 Excellent

Celia

Hyatt Place Sumter / Downtown

Sumter

10/10 Excellent

To avoid the "usual" motel/hotels in close proximity to i 95 corridor, I searched and found this gem of a place about 20 miles off the mainline; it was well worth the extra drive. The hotel was immaculate, appointed beautifully, and staffed with efficient, knowledgeable, and kind folks. My room was the same. I was greatly relieved and did not feel the need to do my usual inspection. I introduced myself by tripping at the entrance due to imbalance of my own making, carrying too many...

Linda

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

Residence Inn Marriott Florence

Florence

10/10 Excellent

Staff were friendly and nice! Very accommodating to both my dogs. Room was clean and nice. Some wallpaper was bubbling but it honestly didn’t bother me. Loved the secure easy access to the building. Hotel was right next to a beautiful memorial park and very easy to get to the civic center. Pool was beautiful even though I didn’t get to use it due to weather. Looked like the pool was handicap accessible with a lift. Breakfast was amazing every morning with lots to choose from. We definitely will...

Anna

A spacious hotel lobby with a long reception desk, seating area, and a clear view of the dining area in the background.

Holiday Inn Express Pembroke by IHG

Pembroke

10/10 Excellent

Kimberly

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

Tru by Hilton Florence I-95

Florence

10/10 Excellent

Robert

Hilton Garden Inn Florence

Florence

10/10 Excellent

Maria

Homewood Suites by Hilton Florence

Florence

10/10 Excellent

Cynthia

Home2 Suites by Hilton Florence, SC

Florence

10/10 Excellent

Alejandra

Frequently Asked Questions

How many pet-friendly hotels will I be able to find in Florence?

Enjoy traveling with your furry pal at one of Expedia's 38 pet-friendly Florence hotels or accommodations.

What's the best time of year to travel to Florence with my pet?

When you travel with your pet, keeping tabs on the weather can help you make the trip more safe and fun for everyone. The hottest months are usually July and August with an average temp of 78°F, while the coldest months are January and February with an average of 50°F. Average annual precipitation for Florence is 54 inches.

What is there to see and do with your pet in Florence?

Known for its museums, Florence has lots to offer visitors including its gardens and entertainment. See the local sights and visit Florence County Museum and Florence National Cemetery. While you're there, make sure you don't miss Dr. Eddie Floyd Tennis Center and Magnolia Mall.

What's the best pet-friendly hotel in Florence?

Quality Inn & Suites Florence Civic Center is a top hotel for people traveling with their pets, and offers a seasonal outdoor pool and a fitness center for its human guests. Two other good options for you and your pet include SpringHill Suites by Marriott Florence and Comfort Inn & Suites Florence Center Area.

Find Pet-friendly Hotels in Florence, SC

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Florence pet-friendly hotels

1. Park Inn by Radisson Florence, SC

2. Comfort Inn & Suites Florence Center Area

3. Hampton Inn & Suites Florence-North-I-95

4. Staybridge Suites Florence - Civic Center by IHG

5. Quality Inn & Suites Florence Civic Center

6. Hilton Garden Inn Florence

7. Homewood Suites by Hilton Florence

8. Home2 Suites by Hilton Florence, SC

9. TownePlace Suites by Marriott Florence

10. Comfort Suites Florence I-95

Top Florence Hotel Reviews

1912 Bed and Breakfast

10/10 Excellent

Frequently Asked Questions

How many pet-friendly hotels will I be able to find in Florence?

What's the best time of year to travel to Florence with my pet?

What is there to see and do with your pet in Florence?

What's the best pet-friendly hotel in Florence?