A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Find Business Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Tonight
Sep 29 - Sep 30
Tomorrow
Sep 30 - Oct 1
This weekend
Oct 2 - Oct 4
Next weekend
Oct 9 - Oct 11

Our top choices for Florida Keys business-friendly hotels

A hotel with a covered entrance, multiple balconies, and palm trees.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A waterfront hotel with multiple balconies, a dock, and boats.

1. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
United States
Susan
₩350,704
₩447,872 total
includes taxes & fees
Sep 30 - Oct 1
Opal Key Resort & Marina, Key West
A swimming pool surrounded by palm trees and a natural rock formation.
A cozy room with wicker furniture, a glass coffee table, and a view of lush greenery outside.
A bar setting with a bartender preparing a drink, a counter with various bottles, and a TV screen in the background.
A spacious lobby with a central seating area, two staircases, and multiple potted plants.

2. Havana Cabana at Key West

Havana Cabana at Key West
New Town
United States
Gustavo
₩150,302
₩254,559 total
includes taxes & fees
Sep 30 - Oct 1
Havana Cabana at Key West
Pool
A modern cafe with a wooden counter, seating area, and shelves stocked with beverages.
A couple holding hands in a tropical setting with palm trees and greenery.
A hotel room with a bed, a sofa, a round table with a book, a window with a view, and a radiator.

3. Blue Flamingo Resort Key West

Blue Flamingo Resort Key West
New Town
United States
Esteban
₩159,983
₩256,149 total
includes taxes & fees
Oct 4 - Oct 5
Blue Flamingo Resort Key West
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious living room with large windows, comfortable seating, and decorative plants.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.
A poolside area with blue chairs and a thatched-roof structure.

4. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Susan
₩269,460
₩357,312 total
includes taxes & fees
Sep 30 - Oct 1
Reefhouse Resort & Marina
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.
A modern office space with a reception desk, computer, and seating area.
An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

5. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Fairfield by Marriott Inn & Suites Key West at The Keys Collection
New Town
United States
Patricia
₩161,134
₩219,352 total
includes taxes & fees
Sep 30 - Oct 1
Fairfield by Marriott Inn & Suites Key West at The Keys Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A tropical resort with a swimming pool, palm trees, and a waterfall.

6. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
United States
RAIBEL
₩175,349
₩275,202 total
includes taxes & fees
Oct 13 - Oct 14
Cheeca Lodge & Spa
A wooden archway leading to a pool area surrounded by lush tropical vegetation.
A beach with palm trees, lounge chairs, and umbrellas.
A beach with palm trees, a sandy shore, and a calm sea under a clear sky.
A large, two-story building with a symmetrical facade, a central entrance with a double door, and a balcony on the upper floor.

7. Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
Northside Resort
United States
Anthony
₩178,737
₩278,776 total
includes taxes & fees
Oct 5 - Oct 6
Parrot Key Hotel & Villas
A hotel with a swimming pool, balconies, and a view of the sea.
A spacious bar area with a wooden counter and green bar stools, a seating area with a sofa and chairs, and a dining area with a table set for two.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.
A balcony with a view of the ocean, a table, chairs, and a railing.

8. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
United States
yendy
₩315,498
₩449,380 total
includes taxes & fees
Oct 4 - Oct 5
Hyatt Centric Key West Resort and Spa
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.
A modern kitchen with a marble island, wooden cabinets, and pendant lighting.
A hotel room with a balcony, a bed, a desk, and two chairs.
A bar area with a thatched roof, wooden chairs, and a poolside view.

9. Hampton Inn Key West FL

Hampton Inn Key West FL
Key West
United States
Jaycie
₩224,976
₩253,098 total
includes taxes & fees
Oct 6 - Oct 7
Hampton Inn Key West FL
A pool area with lounge chairs and a cabana.
A hotel room with a bed, a sofa, a desk with a computer, a chair, and a view of the sea through large windows.
A balcony with a table set for breakfast, overlooking the sea.
A waterfront hotel with a long pier, multiple balconies, and a view of the ocean.

10. Ocean Key Resort - A Noble House Resort

Ocean Key Resort - A Noble House Resort
Key West Historic District
United States
Brian
₩333,728
₩480,908 total
includes taxes & fees
Oct 15 - Oct 16
Ocean Key Resort - A Noble House Resort
View all properties

Top Florida Keys Hotel Reviews

Islander Resort

Islander Resort

10/10 Excellent
"Amazing place would definitely recommend"
Steven 2-night trip
Posted 16 hours ago
Islander Resort
Baker's Cay Resort Key Largo, Curio Collection by Hilton

Baker's Cay Resort Key Largo, Curio Collection by Hilton

10/10 Excellent
"wonderful"
Yamelys 2-night trip
Posted 17 hours ago
Baker's Cay Resort Key Largo, Curio Collection by Hilton
Amara Cay Resort

Amara Cay Resort

8/10 Good
"This resort was absolutely beautiful!! The pool was amazing, a resort style pool. The resort had its own private beach area and a dock. Had plenty of seating everywhere, many cool sitting areas around the property. The only negative thing I could say is that the staff didn’t pick up trash and towels around the pool which seemed odd and it was off season so it wasn’t busy. It’s such a beautiful resort that I would think that would be a priority to keep it clean. Another cool thing is that they have a water taxi and shuttle to their 2 sister resorts which you can utilize all of those amenities as well. They also included bike rentals, paddle boards and kayaking on site which is convenient. You can also bring your private boat there and leave it at the dock for a fee. I would absolutely stay there again!"
Melissa 1-night trip
Posted 19 hours ago
Amara Cay Resort
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

10/10 Excellent
"Ya’ll just need a microwave."
Nathalee 3-night trip
Posted 1 day ago
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"i loved this place beautiful hotel full kitchen perfect for a little trip 100% recommend"
Ysabella 2-night trip
Posted 1 day ago
Waterside Suites & Marina
Sunset Cove Beach Resort

Sunset Cove Beach Resort

10/10 Excellent
"Great getaway for weekend and bring the dog"
Brian 4-night trip
Posted 3 days ago
Sunset Cove Beach Resort

Frequently asked questions

How much do business-friendly hotels in Florida Keys cost?
Prices for business hotels in Florida Keys range between ₩197,918 and ₩480,908 per night. No matter your budget, Expedia can help you locate the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Florida Keys?
Florida Keys has multiple business-friendly hotels with a total average guest review rating of 8.8. Attending a work-related event in Key West? The Perry Hotel & Marina Key West is a 4-stars stay that comes highly recommended by corporate travelers and includes a nearby waterfront and a garden. Another excellent pick for an official business trip is Silver Palms Inn. Also in Key West, it has a 3.5-stars rating and conveniences such as an electric car charging station and a swimming pool.
How many business-friendly hotels are there in Florida Keys?
Florida Keys has 87 business-friendly hotels to pick from. Whether you're attending a conference or meeting or working remotely, these stays are equipped with the amenities you need to be productive.
What are the best cheap business-friendly hotels in Florida Keys?
That depends on which part of Florida Keys your working visit is taking you. If you're traveling to Key West, Best Western Hibiscus Motel meets the needs of business travelers at an affordable price. A spa tub and a restaurant are among its many conveniences. Meeting with clients in Key Largo? Check in to Coconut Palm Inn. Pool sun loungers and a garden help make this inexpensive property a favorite with corporate guests. Business-friendly hotels start from just ₩197,918 a night, so your work trip doesn't have to be costly. Want to explore Florida Keys without blowing your budget? Take a break from your business events to visit cool free attractions like Smathers Beach in Key West. Key Largo also has plenty of things to do that won't cost a penny, including Baker's Cay Resort Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Florida Keys that are also business friendly?
If you're traveling for business in Florida Keys and bringing your family along with you, Expedia will help you find a suitable stay. Eden House in Key West is an ideal option for those juggling work and pleasure. This 3.5-stars property offers all the necessary amenities, like a sauna and a cafe. Hyatt Centric Key West Resort and Spa is another good choice in Key West. Combine corporate travel and quality time with your family at this 4-stars property. A nearby beach and WiFi are two of the many conveniences you'll find here. There are plenty of terrific things to do for the whole family in Key West. Smathers Beach and South Beach promise a great day out.
Are there any 5-star business-friendly hotels in Florida Keys?
While there aren't any 5-star business-friendly hotels in Florida Keys, there are still chic properties to choose from. Work taking you to Key West? The Perry Hotel & Marina Key West is a popular option that has everything you need while you're away from home on business. Amenities at this 4-star property include pillow top mattresses and designer toiletries. Ocean Key Resort - A Noble House Resort is another recommendation that caters to corporate travelers in Key West. Also rated 4 stars and featuring a swimming pool and a resort, you'll find plenty to love about this hotel.
Why book your business-friendly hotel in Florida Keys with Expedia?
Here at Expedia, our top task is to help you land a suitable stay at the right price. From deluxe, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip planned in a few quick clicks.
How can I find cheap business-friendly hotels in Florida Keys?
When work takes you on the road in Florida Keys, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to concierge services and conference spaces, they come with the amenities you need to be productive. You can also refine your search by your budget and preferred star rating to see the cheapest properties.
What is there to do in Florida Keys near my business-friendly hotel?
Whether you like shopping, dining, history or culture, Florida Keys is one place you'll never get bored! The well-known city of Key West has tons of attractions, including Smathers Beach, South Beach and Clarence S. Higgs Memorial Beach Park. If you're planning a work trip to Key Largo, Baker's Cay Resort Beach, Jimmy Johnson's Big Chill and Bluefin Rock Harbor Marina are worth putting on your itinerary.

Explore a world of travel with Expedia