A beach with palm trees, people relaxing on chairs, and colorful kayaks.

Find Business Hotels in Florida Keys

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florida Keys Business Hotels

Tonight
Oct 5 - Oct 6
Tomorrow
Oct 6 - Oct 7
This weekend
Oct 9 - Oct 11
Next weekend
Oct 16 - Oct 18

Our top choices for Florida Keys business-friendly hotels

A hotel with a covered entrance, multiple balconies, and palm trees.
A restaurant interior with wooden beams, a bar area, and a colorful ceiling mural.
A covered balcony with white Adirondack chairs and a small table with flowers, overlooking a turquoise sea and distant shoreline.
A room with a stone wall, a wooden bench, a cactus, and a framed painting.

1. Opal Key Resort & Marina, Key West

Opal Key Resort & Marina, Key West
Old Town Key West
United States
Susan
₩347,148
₩443,331 total
includes taxes & fees
Oct 7 - Oct 8
Opal Key Resort & Marina, Key West
A swimming pool surrounded by palm trees and a natural rock formation.
A covered outdoor seating area with a pool in the background.
A cozy room with wicker furniture, a glass coffee table, and a view of lush greenery outside.
A spacious lobby with a central seating area, two staircases, and multiple potted plants.

2. Havana Cabana at Key West

Havana Cabana at Key West
New Town
United States
Stephanie
₩179,761
₩287,255 total
includes taxes & fees
Nov 1 - Nov 2
Havana Cabana at Key West
A beach with a wooden pier, palm trees, and beach umbrellas.
An outdoor dining area with tables set for guests, overlooking a calm sea and a pier.
An outdoor dining area with tables and chairs, overlooking the ocean.
A resort with a pool, lounge chairs, umbrellas, palm trees, and a view of the ocean.

3. The Reach Key West, Curio Collection by Hilton

The Reach Key West, Curio Collection by Hilton
Old Town Key West
United States
Darlene
₩295,076
₩422,434 total
includes taxes & fees
Oct 25 - Oct 26
The Reach Key West, Curio Collection by Hilton
Pool
A spacious living area with a sofa, chairs, a coffee table, and a foosball table. Large windows offer a view of the outdoor area.
A couple holding hands in a tropical setting with palm trees and greenery.
A modern cafe with a wooden counter, seating area, and shelves stocked with beverages.

4. Blue Flamingo Resort Key West

Blue Flamingo Resort Key West
New Town
United States
Esteban
₩158,499
₩253,770 total
includes taxes & fees
Oct 7 - Oct 8
Blue Flamingo Resort Key West
A hotel with a swimming pool, balconies, and a view of the sea.
A beach wedding setup with white chairs, a wooden arch, and lanterns.
A marina with jet skis docked in front of a hotel with a dock and a boat in the background.
A spacious bar area with a wooden counter and green bar stools, a seating area with a sofa and chairs, and a dining area with a table set for two.

5. Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa
Key West Historic District
United States
yendy
₩289,764
₩419,555 total
includes taxes & fees
Oct 7 - Oct 8
Hyatt Centric Key West Resort and Spa
A pool area with lounge chairs and umbrellas, surrounded by palm trees and a view of the ocean.
A modern kitchen with a marble island, wooden cabinets, and pendant lighting.
A bar area with a thatched roof, wooden chairs, and a poolside view.
A hotel room with a balcony, a bed, a desk, and two chairs.

6. Hampton Inn Key West FL

Hampton Inn Key West FL
Key West
United States
Jaycie
₩226,714
₩255,054 total
includes taxes & fees
Oct 7 - Oct 8
Hampton Inn Key West FL
A dining area with tables set for two, overlooking a beach with palm trees and a sunset view.
A spacious bar area with high ceilings and large windows, offering views of the ocean.
A spacious living room with large windows, comfortable seating, and decorative plants.
A beach with thatched umbrellas, palm trees, and blue lounge chairs.

7. Reefhouse Resort & Marina

Reefhouse Resort & Marina
Key Largo
United States
Manny
₩293,534
₩383,847 total
includes taxes & fees
Oct 7 - Oct 8
Reefhouse Resort & Marina
A wooden archway leading to a pool area surrounded by lush tropical vegetation.
A tall palm tree with a white building in the background.
A large, two-story building with a symmetrical facade, a central entrance with a double door, and a balcony on the upper floor.
A beach with palm trees, a sandy shore, and a calm sea under a clear sky.

8. Parrot Key Hotel & Villas

Parrot Key Hotel & Villas
Northside Resort
United States
Anthony
₩166,202
₩263,886 total
includes taxes & fees
Oct 13 - Oct 14
Parrot Key Hotel & Villas
A pool area with lounge chairs and umbrellas, surrounded by palm trees.
A wooden outdoor dining table set with glassware, candles, and lanterns, surrounded by lush greenery.
A hotel room with a large bed, a wooden nightstand, a desk, a chair, and a window with curtains.
An outdoor patio area with tables and chairs, a bar area with a counter and bar stools, and a TV mounted on the wall.

9. Fairfield by Marriott Inn & Suites Key West at The Keys Collection

Fairfield by Marriott Inn & Suites Key West at The Keys Collection
New Town
United States
Brian
₩173,054
₩232,408 total
includes taxes & fees
Oct 7 - Oct 8
Fairfield by Marriott Inn & Suites Key West at The Keys Collection
A bathroom with a large bathtub, a window with curtains, and a view of palm trees and the sea.
A hotel room with a large bed, a television, a dining area with chairs, a table, and a view of the ocean.
A bar area with a thatched roof, wooden chairs, and a view of the ocean.
A spacious lobby with a seating area, a bar, and a large window providing a view of the outdoors.

10. Cheeca Lodge & Spa

Cheeca Lodge & Spa
Matecumbe
United States
RAIBEL
₩253,324
₩383,009 total
includes taxes & fees
Oct 18 - Oct 19
Cheeca Lodge & Spa
View all properties

Top Florida Keys Hotel Reviews

The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

10/10 Excellent
"All together great"
Joshua 1-night trip
Posted 5 hours ago
The Pelican Key Largo Cottages
Amara Cay Resort

Amara Cay Resort

10/10 Excellent
"Everybody was nice and helpful, the room very clean . 🤗"
Yohana 1-night trip
Posted 6 hours ago
Amara Cay Resort
Reefhouse Resort & Marina

Reefhouse Resort & Marina

10/10 Excellent
"Excellent place"
Manny 4-night trip
Posted 7 hours ago
Reefhouse Resort & Marina
Cheeca Lodge & Spa

Cheeca Lodge & Spa

10/10 Excellent
"Really a nice place. Overall the Keys are an older area with many hotels/resorts showing signs of deferred maintenance. This place was a true 5 Star. Staff is/are unbelievable. 100% recommend."
Scott 1-night trip
Posted 9 hours ago
Cheeca Lodge & Spa
Waterside Suites & Marina

Waterside Suites & Marina

10/10 Excellent
"Clean and affordable to say the least Located closely to many restaurants and stores for essentials"
Guillermo 1-night trip
Posted 10 hours ago
Waterside Suites & Marina
Bayside Inn Key Largo

Bayside Inn Key Largo

10/10 Excellent
"Exactly the experience we wanted. Great views, great location, fishing off the dock."
Jean-luc 2-night trip
Posted 17 hours ago
Bayside Inn Key Largo
Kingsail Resort

Kingsail Resort

10/10 Excellent
"El hotel nos encanto, nos registramos antes de la hora acordada, el personal es maravilloso, la habitación es una mini casa con todo los accesorios necesarios para su comodidad, las camas muy cómodas y limpias, el hospedaje incluye cayak sin costo adicional , ofrecen café free en la piscina, y un ranchon frente al mar con mesas y hasta parrilla para pasar el rato al aire libre. 100 % recomendado"
Armando Jesus 2-night trip
Posted 1 day ago
Kingsail Resort

Frequently asked questions

How much do business-friendly hotels in Florida Keys cost?
Prices for business hotels in Florida Keys range between ₩196,599 and ₩383,009 per night. No matter your budget, Expedia can help you locate the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in Florida Keys?
Florida Keys has multiple business-friendly hotels with a total average guest review rating of 9.1. Attending a work-related event in Key West? The Perry Hotel & Marina Key West is a 4-stars stay that comes highly recommended by corporate travelers and includes a nearby waterfront and a garden. Another excellent pick for an official business trip is Silver Palms Inn. Also in Key West, it has a 3.5-stars rating and conveniences such as an electric car charging station and a swimming pool.
How many business-friendly hotels are there in Florida Keys?
Florida Keys has 87 business-friendly hotels to pick from. Whether you're attending a conference or meeting or working remotely, these stays are equipped with the amenities you need to be productive.
What are the best cheap business-friendly hotels in Florida Keys?
That depends on which part of Florida Keys your working visit is taking you. If you're traveling to Key West, Best Western Hibiscus Motel meets the needs of business travelers at an affordable price. A spa tub and a restaurant are among its many conveniences. Meeting with clients in Key Largo? Check in to Coconut Palm Inn. Pool sun loungers and a garden help make this inexpensive property a favorite with corporate guests. Business-friendly hotels start from just ₩196,599 a night, so your work trip doesn't have to be costly. Want to explore Florida Keys without blowing your budget? Take a break from your business events to visit cool free attractions like Smathers Beach in Key West. Key Largo also has plenty of things to do that won't cost a penny, including Baker's Cay Resort Beach. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
Are there any family-friendly hotels in Florida Keys that are also business friendly?
If you're traveling for business in Florida Keys and bringing your family along with you, Expedia will help you find a suitable stay. Eden House in Key West is an ideal option for those juggling work and pleasure. This 3.5-stars property offers all the necessary amenities, like a sauna and a cafe. Hyatt Centric Key West Resort and Spa is another good choice in Key West. Combine corporate travel and quality time with your family at this 4-stars property. A nearby beach and WiFi are two of the many conveniences you'll find here. There are plenty of terrific things to do for the whole family in Key West. Smathers Beach and South Beach promise a great day out.
Are there any 5-star business-friendly hotels in Florida Keys?
While there aren't any 5-star business-friendly hotels in Florida Keys, there are still chic properties to choose from. Work taking you to Key West? The Perry Hotel & Marina Key West is a popular option that has everything you need while you're away from home on business. Amenities at this 4-star property include pillow top mattresses and designer toiletries. Ocean Key Resort - A Noble House Resort is another recommendation that caters to corporate travelers in Key West. Also rated 4 stars and featuring a swimming pool and a resort, you'll find plenty to love about this hotel.
Why book your business-friendly hotel in Florida Keys with Expedia?
Here at Expedia, our top task is to help you land a suitable stay at the right price. From deluxe, corporate-friendly getaways to affordable motels filled with all the amenities you need, you'll have your next work trip planned in a few quick clicks.
How can I find cheap business-friendly hotels in Florida Keys?
When work takes you on the road in Florida Keys, our "business friendly" filter will help you find the ideal hotel. From included breakfast and free WiFi to concierge services and conference spaces, they come with the amenities you need to be productive. You can also refine your search by your budget and preferred star rating to see the cheapest properties.
What is there to do in Florida Keys near my business-friendly hotel?
Whether you like shopping, dining, history or culture, Florida Keys is one place you'll never get bored! The well-known city of Key West has tons of attractions, including Smathers Beach, South Beach and Clarence S. Higgs Memorial Beach Park. If you're planning a work trip to Key Largo, Baker's Cay Resort Beach, Jimmy Johnson's Big Chill and Bluefin Rock Harbor Marina are worth putting on your itinerary.

Explore a world of travel with Expedia