Grand Isle Vacations

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Where to stay in Grand Isle

Find the best Grand Isle areas and neighborhoods for the activities you enjoy most. Learn more about Grand Isle
Port St Joe is a small Town in the Florida Panhandle

Downtown Port St. Joe

While visiting Downtown Port St. Joe, you might make a stop by sights like Port Saint Joe City Hall and Port St. Joe Marina.

Find hotels in Downtown Port St. Joe

Grand Isle Hotel Deals

MainStay Suites Port Saint Joe South

MainStay Suites Port Saint Joe South

2.5 out of 5
3951 E Highway 98 Port St. Joe FL
Fully refundableReserve now, pay when you stay
The price is ₩221,539 per night from Apr 30 to May 1
₩221,539
₩248,124 total
Apr 30 - May 1
includes taxes & fees
8.6/10 Excellent! (705 reviews)
The room was clean and the staff went out of their way to make us comfortable.

Reviewed on Mar 29, 2026

MainStay Suites Port Saint Joe South
Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG

2.5 out of 5
5627 E Highway 22 State Route Panama City FL
Fully refundable
The price is ₩176,078 per night from Apr 5 to Apr 6
₩176,078
₩190,288 total
Apr 5 - Apr 6
includes taxes & fees
8.4/10 Very Good! (457 reviews)
Okay stay.

Reviewed on Mar 18, 2026

Holiday Inn Express Hotel & Suites Panama City-Tyndall by IHG
Comfort Suites

Comfort Suites

2.5 out of 5
264 N Tyndall Pkwy Panama City FL
Fully refundable
The price is ₩154,968 per night from Apr 5 to Apr 6
₩154,968
₩167,480 total
Apr 5 - Apr 6
includes taxes & fees
8.6/10 Excellent! (729 reviews)
Place is rough. Hopefully it’s under renovation not just repairs. Room was huge and spacious. If you want breakfast go before 8.

Reviewed on Mar 14, 2026

Comfort Suites
See all 2,208 properties in Grand Isle
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Grand Isle vacation package cost?
We make it simple to travel the world, with Grand Isle packages starting from just . You'll have the flexibility to bundle your preferred airlines, hotels and car rental. For the ultimate getaway, why not add a couple of tours and activities to your itinerary?
How do I get a cheap travel package to Grand Isle?
Booking a Grand Isle vacation package with Expedia is one of the easiest ways to save. We offer more than 550 air carriers and 1,000,000 properties throughout the world. With such a broad range to select from, you'll have no worries putting together your perfect adventure.
Where should I stay in Grand Isle?
If you're interested in visiting Mexico Beach, save yourself the stress of commuting and book a hotel nearby. It's one of the top attractions in this neighborhood.
What are the top hotels in Grand Isle?
Beautiful Fully Remodeled Home With Private Pool is one of Grand Isle's most sought-after properties. Secure a room here and you can snooze soundly knowing you're in capable hands.
How far in advance should I book my Grand Isle vacation?
It's always wise to book early. Air carriers generally advertise flight tickets around a year prior to departure, and this is an excellent opportunity to pick up some of the cheapest prices. Boss just told you to take some vacation time next month? No problem! Expedia are never short of fantastic bargains to send you off on the getaway of your dreams, at an affordable price.
What does an Expedia Grand Isle travel package include?
Flights, hotels and a reliable car for all your road trip adventures. Simply select your favorite bundle and gain access to great discounts. Once you've made your booking, add on some experiences and tours and watch your savings pile up. When it comes to crafting your Grand Isle vacation, you're in charge!
What should I know before booking a Grand Isle travel package?
A travel package can be tailored to your budget and is a great way to make your hard-earned dollars stretch further. How little or much you include is up to you. Rental cars, hotels and flights — mix and match whatever combination works with your plans.
Can I choose my airline with a Grand Isle Expedia vacation package?
With a vacation package, you're always in charge. Whether you're eager to fly to Grand Isle in economy or first class, simply select from the available airline options. Expedia has access to more than 550 airline partners across the world.
If I'm not able to travel, can I cancel my Grand Isle vacation package?
Because we understand life can throw you a few curveballs, the answer is yes. For further information, head to our Customer Service Portal. But generally speaking, if you've booked your Grand Isle vacation package in the last 24 hours, you may be able to cancel or change it free of charge. Your airline, hotel or car rental company may impose a fee if you made your booking a while ago.

Discover the most popular places to visit in Grand Isle

T.H. Stone Memorial St. Joseph Peninsula State Park

T.H. Stone Memorial St. Joseph Peninsula State Park

You can take time to visit T.H. Stone Memorial St. Joseph Peninsula State Park during your travels to Port St. Joe. Wander the beautiful beaches in this relaxing area.

T.H. Stone Memorial St. Joseph Peninsula State Park

Port St. Joe Beach

Why not spend a lazy afternoon at Port St. Joe Beach during your trip to Port St. Joe? While you're in the area, stroll along the beautiful beaches.

Port St. Joe Beach

Gulf County Welcome Center

Gulf County Welcome Center is just one of the places to see in Port St. Joe, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the beautiful beaches.

Gulf County Welcome Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.