East Main Street, CO
Grand Junction
Visit East Main Street
Popular places to visit
Canyon View Park
Explore the lovely green spaces of Canyon View Park and enjoy the biking trails in Grand Junction. Check out the notable monuments and lively bars in this family-friendly area.
Colorado Mesa University
Enjoy the collegiate vibe at Colorado Mesa University during your stay in Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its wineries.
St Mary's Medical Center
Though St Mary's Medical Center might be what brings you to town, perhaps you'll have a chance to explore more of Grand Junction while you are here.
Redlands Mesa Golf Club
Enjoy a round of golf in Grand Junction at Redlands Mesa Golf Club. Check out the notable monuments and top-notch restaurants in this family-friendly area.
Mesa County Fairgrounds
Enjoy an outing to Mesa County Fairgrounds during your stay in Grand Junction.
Two Rivers Convention Center
Learn about the events happening at Two Rivers Convention Center during your trip to Grand Junction. Make time to visit the area's notable monuments, or simply enjoy its top-notch restaurants.
East Main Street Hotel Deals
Grand Junction Vacation Rental w/ Fire Pit!
Beautiful home! Super clean, spacious, wonderful place to stay. My family enjoyed it so much they wany to go back. Fit our needs perfectly.
Reviewed on Dec 22, 2025
Grand Vista Hotel
My K9 companion of 13 years passed away from cancer during my stay. I cannot thank the staff enough for supporting me during this difficult period of grieving my loss. Everyone was incredibly understanding and sympathetic. I felt welcomed and at home as if I was around family. Again thank you.
Reviewed on Feb 13, 2026
La Quinta Inn & Suites by Wyndham Grand Junction
Spacious room
Reviewed on Feb 11, 2026
Clarion Inn Grand Junction
Great place for you money with a bar
Reviewed on Feb 2, 2026
Wine Country Inn Palisade
Really nice property and nice rooms
Reviewed on Feb 10, 2026
Doubletree Hotel Grand Junction
Room was clean. Staff was great. Lots of comfy pillows.
Reviewed on Jan 28, 2026
Other neighborhoods around East Main Street
Lincoln Park Historic District
While Lincoln Park Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Western Colorado Botanical Gardens and Western Colorado Center for the Arts.
Washington Park
While Washington Park isn't home to many top sights, Western Colorado Center for the Arts and Western Colorado Botanical Gardens are some notable places to visit nearby.
7th Street Historic District
When in 7th Street Historic District, you can plan a visit to Western Colorado Center for the Arts and Western Colorado Botanical Gardens, some noteworthy sights in the nearby area.
Downtown
While there might not be top attractions in Downtown, you can explore the larger area and discover places like Western Colorado Botanical Gardens and Bananas Fun Park.
Historic Grand Junction
Historic Grand Junction is popular for its abundant dining options, and you can check out Museum of the West, a top attraction in the neighborhood.
Grandview
While there might not be top attractions in Grandview, you can explore the larger area and discover places like Western Colorado Center for the Arts and Western Colorado Botanical Gardens.
