Find hotels in Isle of Palms, Jacksonville

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 31 - Jan 1
Tomorrow
Jan 1 - Jan 2
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Isle of Palms hotels

Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (447)
"Great facility to stay."
United States
Gary
The price is ₩257,694
₩292,483 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (3449)
"Nice stay!"
United States
Mark
The price is ₩193,054
₩219,126 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Margaritaville Jacksonville Beach
2 outdoor pools, open 7:00 AM to 9:00 PM, pool umbrellas, sun loungers
Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
5 km from Isle of Palms
9.2 out of 10, Wonderful, (2618)
"The room was clean, staff was friendly and we loved the location. "
United States
Diane
The price is ₩191,428
₩217,271 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn Jacksonville Beach/Oceanfront
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1002)
"Great friendly staff. Easy booking. "
United States
Modesta
The price is ₩144,870
₩164,428 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Sheraton Jacksonville Hotel
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms
9.0 out of 10, Wonderful, (1006)
"Friendly staff, easy check-in super clean room and facility. Location is excellent as well."
United States
Anthony
The price is ₩165,169
₩184,164 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Exterior
Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
2.5 star property
5 km from Isle of Palms
8.6 out of 10, Excellent, (893)
"Great place to stay highly recommend it"
United States
Taryn
The price is ₩158,359
₩179,737 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Fairfield Inn & Suites by Marriott Jacksonville Beach
Premium bedding, down comforters, pillowtop beds, minibar
World Golf Village Renaissance St. Augustine Resort

World Golf Village Renaissance St. Augustine Resort

World Golf Village Renaissance St. Augustine Resort
4.0 star property
31.6 km from Isle of Palms
8.6 out of 10, Excellent, (1004)
"Beautiful place and clean, Amazing staff, breakfast was excellent. However the bed and pillows HORRIBLE 😔 😟 🙁 😥. "
United States
Giseana
The price is ₩194,350
₩216,700 total
includes taxes & fees
Jan 18 - Jan 19, 2026
World Golf Village Renaissance St. Augustine Resort
Outdoor pool, open 7:00 AM to 7:00 PM, pool umbrellas, sun loungers
One Ocean Resort and Spa

One Ocean Resort and Spa

One Ocean Resort and Spa
4.5 star property
6.7 km from Isle of Palms
8.8 out of 10, Excellent, (1003)
"Need to rethink having guests in middle of this major renovation. Refresh definitely needed. Wouldn’t stay here again until renovation is complete. Staff was accommodating. "
United States
karen
The price is ₩243,602
₩322,916 total
includes taxes & fees
Jan 15 - Jan 16, 2026
One Ocean Resort and Spa
BBQ/picnic area
Salt Air Inn & Suites

Salt Air Inn & Suites

Salt Air Inn & Suites
2.5 star property
6.5 km from Isle of Palms
9.8 out of 10, Exceptional, (415)
"Great stay , convenient locations , friendly staff and well priced "
United States
Grant
Salt Air Inn & Suites
On the beach, windsurfing
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (623)
"The room was great and the staff was exceptional. Would stay here again in a heartbeat. "
United States
Michael
The price is ₩237,395
₩269,443 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Exterior
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
8.8 km from Isle of Palms
9.6 out of 10, Exceptional, (1006)
"Great hotel"
United States
Nima
The price is ₩184,273
₩209,151 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
On the beach, beach shuttle
Casa Marina Hotel

Casa Marina Hotel

Casa Marina Hotel
3.0 star property
4.5 km from Isle of Palms
8.4 out of 10, Very Good, (1001)
"Great breakfast. Easy walk to beach. "
United States
Denise
Casa Marina Hotel
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1010)
"Great location, comfy room, good breakfast and the business center was well equipped and comfortable plus quiet for a workspace during travel."
United States
Darian
The price is ₩175,592
₩199,298 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1000)
"Breakfast was great. The selection was the best I have ever had in the US"
United States
Sandra
The price is ₩194,350
₩220,586 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Hyatt Place Jacksonville / St. Johns Town Center
Outdoor pool, open 8:00 AM to 8:00 PM, pool umbrellas, sun loungers
Seahorse Oceanfront Inn

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.7 km from Isle of Palms
9.0 out of 10, Wonderful, (613)
"The location was ideal if you enjoy shopping eating and entertainment in walking distance ."
United States
Alethia
Seahorse Oceanfront Inn
Exterior
Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport

Home2 Suites by Hilton Jacksonville Airport
3.0 star property
31.3 km from Isle of Palms
8.6 out of 10, Excellent, (1006)
"Clean room and friendly staff"
United States
Marlene
The price is ₩170,855
₩193,920 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Home2 Suites by Hilton Jacksonville Airport
Reception
Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
21.6 km from Isle of Palms
9.0 out of 10, Wonderful, (1009)
"Excellent staff and hotel "
United States
Edward
The price is ₩128,674
₩146,044 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Tru by Hilton Jacksonville South Mandarin
Exterior
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
11.8 km from Isle of Palms
9.2 out of 10, Wonderful, (1000)
"Very nice stay "
United States
Timmothy
The price is ₩164,118
₩186,274 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Indigo Jacksonville-Deerwood Park by IHG
Exterior
Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG
2.5 star property
31.3 km from Isle of Palms
8.6 out of 10, Excellent, (1015)
"Clean room, great service, good breakfast options."
United States
KRITI KUMAR
The price is ₩149,722
₩169,934 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Holiday Inn Express & Suites Jacksonville Airport by IHG
On the beach
Best Western Oceanfront

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1004)
"Great location, clean, comfortable bed, friendly staff"
United States
Jeff
The price is ₩177,348
₩201,291 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Best Western Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most.
Downtown Jacksonville which includes skyline, a city and a river or creek
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Cummer Museum of Art and Gardens which includes interior views and art as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

If you're spending some time in Northwest, Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail are top sights worth seeing.

Top Isle of Palms Hotel Reviews

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

10/10 Excellent
"Nice staff"
Kenneth J. 2-night trip
Posted 1 day ago
Hyatt Regency Jacksonville

Frequently asked questions

What is Isle of Palms like?
Travelers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighborhood.
What's a favorite place to stay in Isle of Palms?
Based on Expedia customer reviews, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is the highest ranked property in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels can I expect to find in Isle of Palms?
Expedia has 39 hotels and other accommodations in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes, you'll find most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a reservation that's non-refundable, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Isle of Palms.
Where can I learn more about changing or cancelling my trip to Isle of Palms?
For more information about changing or cancelling your trip to Isle of Palms, head over to our customer service page.
What is there to do in this Jacksonville Beach neighborhood?
A few places to visit in the area around Isle of Palms include Adventure Landing, Cradle Creek Preserve, and Jacksonville Beach Golf Club. While you're out sightseeing in Jacksonville Beach, be sure to visit other sights like Windsor Parke Golf Club or Players by the Sea.