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Discover 3,152 Isle of Palms hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Wyndham Garden Jacksonville

Holiday Inn Express & Suites Jacksonville Airport by IHG

WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk

Hyatt Place Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Riverfront
Where to stay in Isle of Palms

Downtown Jacksonville
Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Northside
Explore historic communities, visit Jacksonville Zoo and Gardens, Timucuan Preserve, and state parks, or shop at River City Marketplace. Enjoy easy access to Jacksonville International Airport and Amtrak station.

American Beach
If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.
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