La Jolla Mesa Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ₩234,741 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in La Jolla Mesa

Find the best La Jolla Mesa areas and neighborhoods for the activities you enjoy most. Learn more about La Jolla Mesa
Birch Aquarium showing marine life and interior views

La Jolla Shores

2 out of top 10 points of interest in this area
4.5/5(129 area reviews)

If you're spending some time in La Jolla Shores, La Jolla Beach and Birch Aquarium are top sights worth seeing.

Find hotels in La Jolla Shores

La Jolla Mesa Hotel Deals

Lafayette Hotel & Club

Lafayette Hotel & Club

4 out of 5
2223 El Cajon Blvd San Diego CA
Fully refundableReserve now, pay when you stay
The price is ₩338,396 per night from Dec 29 to Dec 30
₩338,396
₩388,313 total
Dec 29 - Dec 30
includes taxes & fees
9.2/10 Wonderful! (1,329 reviews)
The hotel is big on charm and decor. It was in 1937 and the guest rooms haven’t been enlarged or highly modernized. What they did get is a big dash of kitsch. Clashing wall paper, canopied beds, retro appliances, and a huge room bar (you pay per drink). We took a second floor poolside room with a ...

Reviewed on Dec 11, 2025

Lafayette Hotel & Club
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is ₩144,458 per night from Dec 14 to Dec 15
₩144,458
₩167,491 total
Dec 14 - Dec 15
includes taxes & fees
8.8/10 Excellent! (718 reviews)
Great little boutique hotel ! Friendly staff as well

Reviewed on Dec 7, 2025

The DEXTRO Little Italy, BW Premier Collection
Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is ₩139,496 per night from Jan 5 to Jan 6
₩139,496
₩160,344 total
Jan 5 - Jan 6, 2026
includes taxes & fees
8.6/10 Excellent! (1,274 reviews)
clean room

Reviewed on Dec 8, 2025

Hampton Inn San Diego/Mission Valley
See all 9,160 properties in La Jolla Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a La Jolla Mesa vacation package cost?
Maybe less than you might think — from a low , as a matter of fact! By bundling flights, hotels and car rentals into your own custom-made travel package, your La Jolla Mesa escape is only clicks away.
How do I get a cheap travel package to La Jolla Mesa?
Search for flights that fit your busy schedule, add a hotel room to your booking and watch the savings stack up with a La Jolla Mesa vacation package. It's that easy! From hotels and flights to activities and rental cars, Expedia is where your cheap getaway begins. And with over 550 airlines and 1,000,000 hotel options around the globe to choose from, you'll never be short of choice.
Where should I stay in La Jolla Mesa?
Make sightseeing a breeze by staying close to La Jolla Mesa's iconic attractions. La Jolla Cove and University of California, San Diego are two visitor favorites.
What are the top hotels in La Jolla Mesa?
Get your escape off to a great start by booking a stay at Very Private Gated Villa - 2 Master Suites - Ocean. It's one of most sought-after hotels in La Jolla Mesa. Another leading option is Newly Remodeled With Views Of Downtown Ocean And Bay.
How far in advance should I book my La Jolla Mesa vacation?
It's tricky picking the perfect time for airfares, but we generally say the earlier, the better. Plenty of international journeys on Expedia become available to compare up to 12 months in advance. If you can't book ahead, don't despair. Bargain prices occasionally appear just weeks before departure dates.
What does an Expedia La Jolla Mesa travel package include?
With Expedia, you can choose any combination of flights, hotels and car rentals to build your perfect La Jolla Mesa package. Once you've made your booking, you can add on the fun stuff like activities and tours. Don't forget — the more you bundle, the more you stand to save!
What should I know before booking a La Jolla Mesa travel package?
A travel package can be customized for your budget and is a great way to make your budget go further. What you include is completely up to you. Hotels, rental cars and flights — mix and match whatever combination works with your plans.
Can I choose my airline with a La Jolla Mesa Expedia vacation package?
Yes, of course. Expedia has access to more than 550 partner airlines all over the world, so fly with the carrier that suits your travel needs.
If I'm not able to travel, can I cancel my La Jolla Mesa vacation package?
We totally understand that life doesn't always go according to plan. If you've booked a La Jolla Mesa vacation package and need to cancel or amend it, we can help. We suggest taking a look at our Customer Service Portal first for information. But in general, if you've taken out your package within 24 hours, you may be able to cancel and rebook at no cost. If it's more than 24 hours, your hotel, airline or car rental company may impose a fee.

Discover the most popular places to visit in La Jolla Mesa

La Jolla Cove as well as a small group of people

La Jolla Cove

4.5/5(4,767 reviews)

Enjoy world-class shopping, restaurants and beaches in the sparkling “Jewel City” along the ocean.

La Jolla Cove
Hiking the trails at Torrey Pines #hiking

Torrey Pines Golf Course

4.5/5(83 reviews)

Play a round of golf in La Jolla at Torrey Pines Golf Course, and enjoy other activities such as surfing. Wander the beautiful beaches and seaside in this family-friendly area.

Torrey Pines Golf Course
La Jolla Beach

La Jolla Beach

5/5(2 reviews)

Why not spend a lazy afternoon at La Jolla Beach during your trip to La Jolla? Discover the area's beautiful sunsets and top-notch restaurants.

La Jolla Beach
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.