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Our top choices for Lake Nona Medical City hotels

Aloft Orlando Lake Nona

Aloft Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (340 reviews)
"Very clean, cool loft rooms, and very friendly staff. "
United States
Michael
The price is ₩223,176
₩251,074 total
includes taxes & fees
May 7 - May 8
Aloft Orlando Lake Nona

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (627 reviews)
"The staff were very welcoming and helpful. The common areas and rooms are clean, modern and very comfortable. The bathroom was very roomy! A really nice hotel!"
United States
Karen
The price is ₩224,654
₩255,263 total
includes taxes & fees
May 10 - May 11
Courtyard Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (331 reviews)
"Great staff on front desk."
United Kingdom
David
The price is ₩251,258
₩285,488 total
includes taxes & fees
May 10 - May 11
Residence Inn Orlando Lake Nona

Kompose Boutique Resort at Theme Parks

Kompose Boutique Resort at Theme Parks
3.0 star property
30.8 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (3,475 reviews)
"Amazing breakfast and location to disney is a huge plus. "
Canada
Saira
The price is ₩83,817
₩160,539 total
includes taxes & fees
Apr 12 - Apr 13
Kompose Boutique Resort at Theme Parks

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel
3.0 star property
International Drive District, 21.3 km from Lake Nona Medical City
8.4 out of 10, Very Good, (1,109 reviews)
"Clean room, big breakfast, friendly staff "
United States
April
The price is ₩99,247
₩111,652 total
includes taxes & fees
Apr 30 - May 1
DASKK Orlando Hotel near Universal Blvd, an Ascend Collection Hotel

Universal's Stella Nova Resort

Universal's Stella Nova Resort
3.0 star property
18.6 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (663 reviews)
"We were only there for a short time but the staff were very friendly and helpful and the room was clean and comfortable. Would love to stay again. "
Canada
Kristara
The price is ₩274,906
₩309,268 total
includes taxes & fees
May 7 - May 8
Universal's Stella Nova Resort

La Quinta Inn & Suites by Wyndham Orlando Airport

La Quinta Inn & Suites by Wyndham Orlando Airport
3.0 star property
Airport North, 10.9 km from Lake Nona Medical City
7.4 out of 10, Good, (1,681 reviews)
"Perfect location!"
Canada
Necia
The price is ₩131,689
₩148,169 total
includes taxes & fees
Apr 19 - Apr 20
La Quinta Inn & Suites by Wyndham Orlando Airport

Hyatt House Orlando International Drive

Hyatt House Orlando International Drive
4.0 star property
International Drive District, 20.2 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1,696 reviews)
"Friendly staff and rooms were clean."
United States
Maritza
The price is ₩187,705
₩211,167 total
includes taxes & fees
May 3 - May 4
Hyatt House Orlando International Drive

Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport
4.0 star property
7.7 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,094 reviews)
"Great pool area!"
United States
Terry
The price is ₩338,460
₩380,775 total
includes taxes & fees
Apr 26 - Apr 27
Hyatt Regency Orlando International Airport

Hampton Inn & Suites Orlando Airport @ Gateway Village

Hampton Inn & Suites Orlando Airport @ Gateway Village
3.0 star property
Airport North, 10.6 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (2,601 reviews)
"We loved the location! "
United States
Brittany
The price is ₩156,342
₩175,884 total
includes taxes & fees
May 3 - May 4
Hampton Inn & Suites Orlando Airport @ Gateway Village

La Quinta Inn & Suites by Wyndham Orlando UCF

La Quinta Inn & Suites by Wyndham Orlando UCF
3.0 star property
25.4 km from Lake Nona Medical City
8.6 out of 10, Excellent, (2,733 reviews)
"Great location & breakfast"
Australia
Myles
The price is ₩136,936
₩154,053 total
includes taxes & fees
Apr 12 - Apr 13
La Quinta Inn & Suites by Wyndham Orlando UCF

DoubleTree by Hilton at the Entrance to Universal Orlando

DoubleTree by Hilton at the Entrance to Universal Orlando
4.0 star property
Florida Center, 21.7 km from Lake Nona Medical City
8.4 out of 10, Very Good, (6,869 reviews)
"Staff is very friendly and helpful"
United States
Karla
The price is ₩158,293
₩178,098 total
includes taxes & fees
May 3 - May 4
DoubleTree by Hilton at the Entrance to Universal Orlando

Hyatt Place Orlando Airport

Hyatt Place Orlando Airport
3.0 star property
Airport North, 11 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,680 reviews)
"This was such a nice friendly place! "
United States
Cheryl
The price is ₩155,189
₩174,588 total
includes taxes & fees
Apr 27 - Apr 28
Hyatt Place Orlando Airport

Ramada by Wyndham Suites Orlando Airport

Ramada by Wyndham Suites Orlando Airport
3.0 star property
Airport North, 10.4 km from Lake Nona Medical City
8.2 out of 10, Very Good, (5,536 reviews)
"Nice and close to airport, kids liked the pool"
United States
Jennifer
The price is ₩155,632
₩175,097 total
includes taxes & fees
May 3 - May 4
Ramada by Wyndham Suites Orlando Airport

Cambria Hotel Orlando Airport

Cambria Hotel Orlando Airport
3.0 star property
11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1,903 reviews)
"Comfortable stay and near airport "
United States
Maira
The price is ₩149,499
₩168,186 total
includes taxes & fees
May 5 - May 6
Cambria Hotel Orlando Airport

Rosen Shingle Creek

Rosen Shingle Creek
4.5 star property
16.9 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (4,690 reviews)
"Great family place to stay. "
United States
Alberto
The price is ₩223,472
₩251,407 total
includes taxes & fees
May 9 - May 10
Rosen Shingle Creek

Orlando Palms Hotel

Orlando Palms Hotel
2.5 star property
14.9 km from Lake Nona Medical City
7.8 out of 10, Good, (2,594 reviews)
" Clean quiet and friendly staff ut was a great stay i would stay there again whenever im in town"
United States
Lakisha
The price is ₩116,318
₩148,499 total
includes taxes & fees
Apr 15 - Apr 16
Orlando Palms Hotel

Hyatt House Orlando Airport

Hyatt House Orlando Airport
3.5 star property
Airport North, 10.5 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (3,022 reviews)
"Clean room, early check in, helpful/friendly staff, awesome pool & great breakfast! "
Canada
Jillian
The price is ₩193,617
₩217,819 total
includes taxes & fees
Apr 28 - Apr 29
Hyatt House Orlando Airport

Wingate by Wyndham - Orlando International Airport

Wingate by Wyndham - Orlando International Airport
3.0 star property
Airport North, 11.1 km from Lake Nona Medical City
8.8 out of 10, Excellent, (3,879 reviews)
"Rooms nice and clean, and breakfast was good"
United States
Edward
The price is ₩160,805
₩180,906 total
includes taxes & fees
Apr 28 - Apr 29
Wingate by Wyndham - Orlando International Airport

Hampton Inn Orlando-International Airport

Hampton Inn Orlando-International Airport
2.5 star property
Airport North, 10.8 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1,850 reviews)
"Great location - tons of food options to walk to. "
United States
Kenneth
The price is ₩144,503
₩162,566 total
includes taxes & fees
May 4 - May 5
Hampton Inn Orlando-International Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Downtown Orlando

Orlando's historic core boasts art galleries, retail, restaurants, and nightclubs, with attractions like Lake Eola Park, Linton E. Allen Memorial Fountain, and performing arts theaters, all accessible via public transportation.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighborhood that travelers like for its restaurants.
What's a favorite place to stay in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels are there in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodations, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available in Lake Nona Medical City.
Where can I learn more about changing or cancelling my trip to Lake Nona Medical City?
For more information about changing or cancelling your trip to Lake Nona Medical City, click here.
What is there to do around this Orlando neighborhood?
Eagle Creek Golf Club, USTA National Campus, and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Moss Park are a couple of other sights to visit.