What's it like in Lake Nona Medical City?

Lake Nona Medical City is a neighborhood that travelers like for its restaurants.

What's a favorite place to stay in Lake Nona Medical City?

Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona .

How many hotels are there in Lake Nona Medical City?

Expedia has 5 Lake Nona Medical City hotels and other accommodations, and one might make a good home base for venturing out into the greater Orlando area.

If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?

Yes, the majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available in Lake Nona Medical City.

Where can I learn more about changing or cancelling my trip to Lake Nona Medical City?

For more information about changing or cancelling your trip to Lake Nona Medical City, click here .

What is there to do around this Orlando neighborhood?

Eagle Creek Golf Club, USTA National Campus, and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.

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Dates

March 2026

April 2026

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Our top choices for Lake Nona Medical City hotels

Aloft Orlando Lake Nona

Lake Nona Medical City

Kendra

₩255,447 total

includes taxes & fees

Mar 22 - Mar 23

Courtyard Orlando Lake Nona

Lake Nona Medical City

Jana

₩292,510 total

includes taxes & fees

Mar 8 - Mar 9

Residence Inn Orlando Lake Nona

Lake Nona Medical City

David

₩323,742 total

includes taxes & fees

Mar 8 - Mar 9

Kompose Boutique Resort at Theme Parks

30.8 km from Lake Nona Medical City

caleb

₩151,068 total

includes taxes & fees

Mar 1 - Mar 2

Hyatt House Orlando International Drive

International Drive District, 20.2 km from Lake Nona Medical City

Danqing

₩178,976 total

includes taxes & fees

Feb 24 - Feb 25

La Quinta Inn & Suites by Wyndham Orlando Airport

Airport North, 10.9 km from Lake Nona Medical City

Ahmad Taha

₩170,385 total

includes taxes & fees

Mar 2 - Mar 3

Vacation Village Orlando, Celebration

25.4 km from Lake Nona Medical City

Alicia

₩167,791 total

includes taxes & fees

Mar 23 - Mar 24

Rosen Shingle Creek

16.9 km from Lake Nona Medical City

Steven

₩219,978 total

includes taxes & fees

Mar 2 - Mar 3

Wyndham Garden Orlando Airport

Belle Isle, 11.9 km from Lake Nona Medical City

Justin Paul

₩190,864 total

includes taxes & fees

Mar 3 - Mar 4

Studio Suite, 1 King Bed, Accessible, Non Smoking (Mobility/Hearing Accessible) | Premium bedding, in-room safe, desk, blackout drapes

Ramada by Wyndham Suites Orlando Airport

Airport North, 10.4 km from Lake Nona Medical City

Aniese

₩161,810 total

includes taxes & fees

Mar 10 - Mar 11

Hampton Inn & Suites Orlando Airport @ Gateway Village

Airport North, 10.6 km from Lake Nona Medical City

Eugene

₩238,820 total

includes taxes & fees

Mar 16 - Mar 17

Westgate Lakes Resort & Spa Universal Studios Area

20.7 km from Lake Nona Medical City

Christopher

₩207,443 total

includes taxes & fees

Feb 24 - Feb 25

Holiday Inn Express Orlando International Airport by IHG

11.1 km from Lake Nona Medical City

Veronika

₩219,895 total

includes taxes & fees

Feb 24 - Feb 25

Poolside Family Suite - Exterior Entry (Includes Early Park Admission*) | View from room

Universal's Cabana Bay Beach Resort

Florida Center, 22.2 km from Lake Nona Medical City

Lyndon

₩216,399 total

includes taxes & fees

Feb 25 - Feb 26

Hyatt House Orlando Airport

Airport North, 10.5 km from Lake Nona Medical City

Kathy

₩261,956 total

includes taxes & fees

Mar 2 - Mar 3

Country Inn & Suites by Radisson, Orlando Airport, FL

Airport North, 11 km from Lake Nona Medical City

Edward

₩145,248 total

includes taxes & fees

Mar 2 - Mar 3

La Quinta Inn & Suites by Wyndham Orlando UCF

25.4 km from Lake Nona Medical City

Herminia

₩174,274 total

includes taxes & fees

Mar 15 - Mar 16

Cambria Hotel Orlando Airport

11.1 km from Lake Nona Medical City

Gloria

₩199,151 total

includes taxes & fees

Mar 2 - Mar 3

Orlando Palms Hotel

14.9 km from Lake Nona Medical City

Lisa

₩129,029 total

includes taxes & fees

Mar 6 - Mar 7

Holiday Inn Orlando International Airport by IHG

Airport North, 10.8 km from Lake Nona Medical City

Linda

₩174,420 total

includes taxes & fees

Mar 22 - Mar 23

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