Find hotels in Lake Nona Medical City, Orlando

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Lake Nona Medical City hotels

Courtyard Orlando Lake Nona

Courtyard Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.4 out of 10, Exceptional, (602)
"Clean room and pleasant staff"
United States
Michelle
The price is ₩244,952
₩278,324 total
includes taxes & fees
Jan 18 - Jan 19
Courtyard Orlando Lake Nona

Aloft Orlando Lake Nona

Aloft Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.8 out of 10, Exceptional, (291)
"Our stay was great!"
United States
Kendra
The price is ₩247,104
₩277,992 total
includes taxes & fees
Jan 18 - Jan 19
Aloft Orlando Lake Nona

Residence Inn Orlando Lake Nona

Residence Inn Orlando Lake Nona
3.0 star property
Lake Nona Medical City
9.6 out of 10, Exceptional, (327)
"Very clean hotel and spacious room with comfortable seating and kitchen area. The location was great for me as I was there visiting someone in an area hospital. There are also restaurants and coffee shops right outside the entrance. "
United States
Sharon
The price is ₩272,491
₩309,626 total
includes taxes & fees
Feb 8 - Feb 9
Residence Inn Orlando Lake Nona

Meliá Orlando Celebration

Meliá Orlando Celebration
4.0 star property
26.1 km from Lake Nona Medical City
8.6 out of 10, Excellent, (1576)
"Very nice property, clean, with a lot of amenities, we will be back for sure!!!!"
United States
Licet
The price is ₩134,796
₩205,635 total
includes taxes & fees
Jan 25 - Jan 26
Meliá Orlando Celebration

The Delaney Hotel

The Delaney Hotel
3.5 star property
20.2 km from Lake Nona Medical City
9.6 out of 10, Exceptional, (1043)
"Very nice small hotel. The Delaney Tavern was a great hotel restaurant to visit and the overall hospitality of the whole property was fantastic! "
United States
Salvador
The Delaney Hotel

Wyndham Lake Buena Vista – Disney Springs® Area

Wyndham Lake Buena Vista – Disney Springs® Area
4.0 star property
23.2 km from Lake Nona Medical City
8.8 out of 10, Excellent, (2799)
"Clean room, staff very helpful, and very convenient to Disney Springs. "
United States
David
The price is ₩158,146
₩236,784 total
includes taxes & fees
Jan 11 - Jan 12
Wyndham Lake Buena Vista – Disney Springs® Area

Wyndham Garden Lake Buena Vista – Disney Springs® Area

Wyndham Garden Lake Buena Vista – Disney Springs® Area
3.5 star property
23.2 km from Lake Nona Medical City
8.2 out of 10, Very Good, (3911)
"Perfect place to stay to get to Disney!"
United States
Todd and Danielle
The price is ₩114,794
₩187,845 total
includes taxes & fees
Jan 12 - Jan 13
Wyndham Garden Lake Buena Vista – Disney Springs® Area

AC Hotel by Marriott Orlando Lake Buena Vista

AC Hotel by Marriott Orlando Lake Buena Vista
3.5 star property
22.5 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (1721)
"Great stay "
United States
Giovanni
The price is ₩191,869
₩215,853 total
includes taxes & fees
Jan 26 - Jan 27
AC Hotel by Marriott Orlando Lake Buena Vista

Hilton Vacation Club Grand Beach Orlando

Hilton Vacation Club Grand Beach Orlando
3.0 star property
21.7 km from Lake Nona Medical City
9.4 out of 10, Exceptional, (1455)
"Great homey hotel! Such a nice quiet reprieve after a busy cruise."
United States
Jessica
The price is ₩154,124
₩214,161 total
includes taxes & fees
Jan 25 - Jan 26
Hilton Vacation Club Grand Beach Orlando

Element Orlando Universal Blvd.

Element Orlando Universal Blvd.
3.0 star property
International Drive District, 20.7 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (1995)
"Wonderful stay, clean, dog friendly, great location"
United States
Beverly
The price is ₩158,929
₩178,794 total
includes taxes & fees
Jan 25 - Jan 26
Element Orlando Universal Blvd.

Days Inn by Wyndham Orlando Conv. Center/International Dr

Days Inn by Wyndham Orlando Conv. Center/International Dr
2.0 star property
International Drive District, 19.2 km from Lake Nona Medical City
8.2 out of 10, Very Good, (2548)
"Enjoyed staying here and very convenient "
United States
Rachael
The price is ₩92,401
₩103,952 total
includes taxes & fees
Jan 27 - Jan 28
Days Inn by Wyndham Orlando Conv. Center/International Dr

Spectrum Resort Villas Orlando and Waterparks

Spectrum Resort Villas Orlando and Waterparks
4.0 star property
33 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (865)
"Great location for a family vacation"
United States
Deanne
The price is ₩333,220
₩710,512 total
includes taxes & fees
Jan 13 - Jan 14
Spectrum Resort Villas Orlando and Waterparks

Aloft Orlando Lake Buena Vista

Aloft Orlando Lake Buena Vista
3.0 star property
21.7 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1935)
"Good place to stay "
United States
victor
The price is ₩118,852
₩133,708 total
includes taxes & fees
Jan 25 - Jan 26
Aloft Orlando Lake Buena Vista

Drury Plaza Hotel Orlando - Disney Springs Area

Drury Plaza Hotel Orlando - Disney Springs Area
3.0 star property
22.9 km from Lake Nona Medical City
9.8 out of 10, Exceptional, (5513)
"Great stay!"
United States
Kiran
The price is ₩234,067
₩263,326 total
includes taxes & fees
Jan 27 - Jan 28
Drury Plaza Hotel Orlando - Disney Springs Area

Hilton Grand Vacations Club SeaWorld® Orlando

Hilton Grand Vacations Club SeaWorld® Orlando
4.0 star property
19.5 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2019)
"Clean room, great accommodations "
United States
Christina Monet
The price is ₩164,393
₩242,038 total
includes taxes & fees
Jan 25 - Jan 26
Hilton Grand Vacations Club SeaWorld® Orlando

Candlewood Suites Orlando - Lake Buena Vista by IHG

Candlewood Suites Orlando - Lake Buena Vista by IHG
2.5 star property
23 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (2335)
"Nice place, clean room."
United States
Paul
The price is ₩108,707
₩138,602 total
includes taxes & fees
Jan 12 - Jan 13
Candlewood Suites Orlando - Lake Buena Vista by IHG

Comfort Suites Near Universal Orlando Resort

Comfort Suites Near Universal Orlando Resort
2.5 star property
Florida Center, 21.6 km from Lake Nona Medical City
8.8 out of 10, Excellent, (1120)
"Great staff, clean, comfortable and very good breakfast"
United States
Tammie
The price is ₩168,278
₩189,312 total
includes taxes & fees
Jan 25 - Jan 26
Comfort Suites Near Universal Orlando Resort

Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG
3.0 star property
20.9 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1673)
"Quick easy check in and great location "
United States
Blaine
The price is ₩127,549
₩143,493 total
includes taxes & fees
Jan 12 - Jan 13
Holiday Inn & Suites Orlando I-Drive Theme Parks by IHG

Hilton Vacation Club Grande Villas Orlando

Hilton Vacation Club Grande Villas Orlando
3.5 star property
22.5 km from Lake Nona Medical City
9.2 out of 10, Wonderful, (2884)
"Good hotel"
United States
Ananta
The price is ₩146,609
₩197,547 total
includes taxes & fees
Jan 20 - Jan 21
Hilton Vacation Club Grande Villas Orlando

Staybridge Suites Orlando Airport South by IHG

Staybridge Suites Orlando Airport South by IHG
3.0 star property
Airport North, 10.5 km from Lake Nona Medical City
9.0 out of 10, Wonderful, (1858)
"Nice room and friendly staff."
United States
Eric
The price is ₩220,312
₩247,851 total
includes taxes & fees
Jan 27 - Jan 28
Staybridge Suites Orlando Airport South by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Downtown Orlando

Orlando's historic core boasts art galleries, retail, restaurants, and nightclubs, with attractions like Lake Eola Park, Linton E. Allen Memorial Fountain, and performing arts theaters, all accessible via public transportation.

Top Lake Nona Medical City Hotel Reviews

Frequently asked questions

What's it like in Lake Nona Medical City?
Lake Nona Medical City is a neighborhood that travelers like for its restaurants.
What's a favorite place to stay in Lake Nona Medical City?
Based on Expedia customer reviews, Aloft Orlando Lake Nona is the highest ranked property in Lake Nona Medical City. This hotel offers a restaurant and an outdoor pool. Other favorite options in the area include Residence Inn Orlando Lake Nona and Courtyard Orlando Lake Nona.
How many hotels are there in Lake Nona Medical City?
Expedia has 5 Lake Nona Medical City hotels and other accommodations, and one might make a good home base for venturing out into the greater Orlando area.
If I need to cancel my hotel reservation in Lake Nona Medical City, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to review the best options available in Lake Nona Medical City.
Where can I learn more about changing or cancelling my trip to Lake Nona Medical City?
For more information about changing or cancelling your trip to Lake Nona Medical City, click here.
What is there to do around this Orlando neighborhood?
Eagle Creek Golf Club, USTA National Campus, and Austin-Tindall Regional Park are just a few of the places to visit in and around Lake Nona Medical City. When you're sightseeing around the area, Lake Hart and Kissimmee Bay Country Club are a couple of other sights to visit.