The entrance to the Kentucky Science Center with a large circular structure in the foreground.

Find hotels near Louisville Science Center, Louisville from ₩162,624

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Our top choices for Louisville Science Center hotels

A wooden staircase with a balustrade leading to a landing.
A dining area with brick walls, wooden shelves, and tables set for a meal.
A brick building with a covered porch, columns, and potted plants.
A two-story brick building with a white porch and a sign reading "Hotel".

1. Market Street Inn

Market Street Inn
2.1 km from Louisville Science Center
United States
Holly
₩262,197
₩296,282 total
includes taxes & fees
Oct 12 - Oct 13
Market Street Inn
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
A bar with shelves of liquor bottles and a bartender preparing drinks.
A multi-story hotel with a classic facade, large windows, and a modern glass building adjacent to it.
A modern living room with a leather sectional sofa, a glass coffee table, and a view of the city skyline through large windows.

2. Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Anthony
₩317,285
₩373,318 total
includes taxes & fees
Oct 29 - Oct 30
Hotel Distil, Autograph Collection
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
A room with a red velvet sofa, a blue armchair, and a small round table with books.
A room with a large mirror, a wooden dresser, a red patterned rug, and a door with a wreath.
An outdoor patio with red furniture, including a table and chairs, and two red umbrellas providing shade.

3. DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast
Old Louisville, 2.8 km from Louisville Science Center
United States
Casey
₩244,156
₩283,388 total
includes taxes & fees
Oct 5 - Oct 6
DuPont Mansion Bed & Breakfast
A grand lobby with ornate columns, plush seating, and a chandelier.
A grand lobby with ornate ceiling, multiple seating areas, and a staircase.
A grand dining area with ornate ceiling, chandeliers, and a bar area with a sign reading "Cigar Bar".
A grand lobby with ornate ceiling and chandeliers, a large vase, and a seating area with multiple sofas and armchairs.

4. The Brown Hotel

The Brown Hotel
Downtown Louisville, 1.2 km from Louisville Science Center
United States
Meghan
₩179,941
₩211,707 total
includes taxes & fees
Oct 25 - Oct 26
The Brown Hotel
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
A spacious hotel lobby with a central seating area, stone accent walls, and a chandelier.
A spacious lobby with a large seating area, a chandelier, and a patterned rug.
A modern hotel with multiple floors, large windows, and a prominent sign for Homewood Suites.

5. Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY
Downtown Louisville, 0.2 km from Louisville Science Center
United States
Kelly
₩160,466
₩188,804 total
includes taxes & fees
Oct 25 - Oct 26
Homewood Suites by Hilton Louisville Downtown, KY
A modern hotel lobby with a reception desk, seating area, and a staircase leading to the upper floor.
A modern bedroom with a bed, a blue sofa, a large rug, and a TV on the wall.
A modern KFC building with large glass windows, a prominent sign, and a well-lit entrance area.
A modern, well-lit room with a large bed, a green sofa, a small round table, and a kitchen area in the background.

6. Stellar Suites

Stellar Suites
East Market District, 2.2 km from Louisville Science Center
United States
Kevin
₩131,789
₩222,976 total
includes taxes & fees
Oct 25 - Oct 26
Stellar Suites
A modern bar area with a circular bar, multiple seating options, and a large screen.
A modern interior with a central wooden table, refrigerated beverage dispensers, and shelves stocked with snacks and condiments.
A modern lobby with a fireplace, seating area, and a reception desk.
A modern living room with a sectional sofa, a small table, and a floor lamp. Large windows offer a view of a cityscape and a building with glass windows.

7. Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row
Downtown Louisville, 1.2 km from Louisville Science Center
United States
Erin
₩138,216
₩162,624 total
includes taxes & fees
Oct 25 - Oct 26
Cambria Hotel Louisville Downtown-Whiskey Row
A modern interior with a fireplace, bookshelves, a green sofa, and leather chairs.
A modern hotel room with a large bed, a desk with a flat-screen TV, a green armchair, and a view of the city through large windows.
A modern restaurant interior with a staircase, round tables, and a brick wall.
A building with a sign reading "THE GRADY" at the entrance.

8. The Grady

The Grady
Downtown Louisville, 0.2 km from Louisville Science Center
United States
Bruce
₩230,203
₩270,858 total
includes taxes & fees
Oct 4 - Oct 5
The Grady
An outdoor terrace with tables and chairs, large windows, and a view of the city skyline at sunset.
A modern hotel lobby with a reception desk, seating area, and a large abstract ceiling artwork.
A modern hotel lobby with a brick wall, grey sofas, a coffee table, and a large TV screen displaying "TEMPO by Hilton".
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV, and a large window offering a city view.

9. Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu
Phoenix Hill, 2.1 km from Louisville Science Center
United States
Addison
₩163,763
₩192,684 total
includes taxes & fees
Oct 4 - Oct 5
Tempo By Hilton Louisville Downtown Nulu
A spacious lobby with a high ceiling, a central chandelier, and seating areas with tables and chairs.
A modern interior with a fireplace, bookshelves, and seating areas.
A lobby with a marble floor, a reception desk, and a large chandelier.
A modern building entrance with a glass facade, wooden ceiling, and illuminated fixtures.

10. Omni Louisville Hotel

Omni Louisville Hotel
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Samantha
₩340,446
₩400,570 total
includes taxes & fees
Oct 30 - Oct 31
Omni Louisville Hotel
An outdoor seating area with sofas and tables, a fire feature, and a clock tower in the background.
A modern living room with a sofa, a coffee table, a side table with a plant, and a view of a building with a clock tower.
A hotel with a prominent sign, a central courtyard with a sculpture, and a dome structure in the background.
A modern lobby with a central reception desk, seating area, and a large abstract wall art piece.

11. Hotel Bourré Bonne Louisville, Curio Collection by Hilton

Hotel Bourré Bonne Louisville, Curio Collection by Hilton
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Cameron
₩240,698
₩283,205 total
includes taxes & fees
Oct 11 - Oct 12
Hotel Bourré Bonne Louisville, Curio Collection by Hilton
A classical gold statue in front of a multi-story building with large windows and a brick facade.
A cozy room with wooden walls, a table with a lamp, and shelves displaying books and decorative items.
A steam fountain in a brick alleyway.
A cozy room with a geometric-patterned ceiling, a sofa, and a chair.

12. 21c Museum Hotel Louisville

21c Museum Hotel Louisville
Downtown Louisville, < 0.1 km from Louisville Science Center
United States
Matt
₩226,705
₩273,442 total
includes taxes & fees
Oct 25 - Oct 26
21c Museum Hotel Louisville
An outdoor seating area with wicker furniture and a fire pit.
A modern living room with a sofa, armchairs, a coffee table, and a TV.
A modern lounge area with seating, tables, and a view of the city through large windows.
A modern hotel lobby with a large central table, multiple seating areas, and large windows offering city views.

13. Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown
Downtown Louisville, 0.3 km from Louisville Science Center
United States
Barbara
₩147,437
₩173,473 total
includes taxes & fees
Oct 25 - Oct 26
Towneplace Suites By Marriott Louisville Downtown
An indoor dining area with wooden tables and chairs, a bar area, and a view of the street outside.
A modern lounge area with a pool table, comfortable seating, a fireplace, and a brick accent wall.
A modern bar area with sofas, tables, and a bar stocked with bottles.
A modern coffee shop interior with a central island, wooden counter, and large windows.

14. Aloft by Marriott Louisville Downtown

Aloft by Marriott Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Angela
₩193,438
₩227,598 total
includes taxes & fees
Oct 25 - Oct 26
Aloft by Marriott Louisville Downtown
A bar area with a neon 'CHECK IN' sign, a variety of liquor bottles, and a modern seating arrangement.
A modern hotel room with a large bed, a desk with a chair, a TV mounted on the wall, and a window with a city view.
A modern living room with a sofa, ottomans, a coffee table, and a rug.
A cozy living room with a fireplace, a black leather sofa, and a patterned rug.

15. Moxy Louisville Downtown

Moxy Louisville Downtown
Downtown Louisville, 0.9 km from Louisville Science Center
United States
Bryan
₩171,564
₩201,863 total
includes taxes & fees
Oct 18 - Oct 19
Moxy Louisville Downtown
A modern bar area with a marble countertop, seating, and a central bar stocked with bottles.
A modern hotel building with a prominent AC Hotel NULU sign, multiple floors, and a well-lit entrance.
A modern interior with a central seating area, a television screen, and a wooden partition with various items displayed.
A modern restaurant with high ceilings, large windows, and a mix of round and rectangular tables.

16. AC Hotel Louisville Downtown

AC Hotel Louisville Downtown
East Market District, 2.1 km from Louisville Science Center
United States
Jen
₩191,803
₩225,675 total
includes taxes & fees
Oct 25 - Oct 26
AC Hotel Louisville Downtown
A room with a checkered floor, leather armchairs, a sofa, and a small table with a glass. There are windows with arched tops and a view of buildings outside.
A bar area with a wooden bar counter, two stools, a chandelier, and a mirror.
A bedroom with a bed, a chair, a TV, and a window with curtains.
A yellow coffee shop counter with a menu board above, displaying various coffee and food items.

17. Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt
East Market District, 2.1 km from Louisville Science Center
United States
Tyler
₩206,667
₩243,165 total
includes taxes & fees
Oct 26 - Oct 27
Hotel Genevieve part of JdV by Hyatt
A covered patio with a stone wall, a glass table, and a bench.
A stone house with a balcony, a front door, and a staircase leading to the entrance.
Staircase
A grand room with a fireplace, a staircase, and a chandelier.

18. Central Park Bed & Breakfast

Central Park Bed & Breakfast
Old Louisville, 3 km from Louisville Science Center
United States
Brittany
₩228,890
₩265,682 total
includes taxes & fees
Oct 5 - Oct 6
Central Park Bed & Breakfast
A modern interior with large windows offering a city view, a circular light fixture, and leather seating.
A modern bar with a long counter, multiple shelves of liquor bottles, and cushioned bar stools.
A spacious room with a large dining table, comfortable seating, a sofa, and a view of a bridge.
A nighttime view of The GALT and The Galthouse buildings with illuminated signage, a busy street with light trails from moving vehicles, and a modern urban setting.

19. Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
Downtown Louisville, 0.5 km from Louisville Science Center
United States
Saud
₩194,537
₩228,893 total
includes taxes & fees
Oct 25 - Oct 26
Galt House Hotel Trademark Collection by Wyndham
A modern building with a restaurant on the ground floor, featuring large windows and outdoor seating.
A modern hotel room with a large window offering a city view, a cozy seating area with a sofa and chairs, a dining table with lamps, and a wooden floor.
A spacious lobby with a bar area, seating arrangements, and a visible kitchen bar.
A reception area with marble counters, modern pendant lighting, and potted orchids.

20. Louisville Marriott Downtown

Louisville Marriott Downtown
Downtown Louisville, 0.8 km from Louisville Science Center
United States
Jacobi
₩287,020
₩337,708 total
includes taxes & fees
Oct 12 - Oct 13
Louisville Marriott Downtown
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Compare popular hotels close to Louisville Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A wooden staircase with a balustrade leading to a landing.
Market Street Inn
9.8
Exceptional
125 reviews
View
An indoor dining area with tables set for guests, surrounded by potted plants and hanging lights.
Hotel Distil, Autograph Collection
9.6
Exceptional
507 reviews
View
A historic building with a grand entrance, steps leading up to the door, and a sign indicating it is a bed and breakfast.
DuPont Mansion Bed & Breakfast
9.6
Exceptional
147 reviews
View
A grand lobby with ornate columns, plush seating, and a chandelier.
The Brown Hotel
9.4
Exceptional
1,329 reviews
View
A spacious indoor patio with a fire pit, wooden pergola, and comfortable seating areas.
Homewood Suites by Hilton Louisville Downtown, KY
9.4
Exceptional
1,000 reviews
View

Top Louisville Science Center Hotel Reviews

The Grady

The Grady

10/10 Excellent
"Great place to stay in downtown Louisville. Staff is always friendly and helpful."
Ralph 1-night trip
Posted 17 hours ago
The Grady
Holiday Inn Louisville Downtown by IHG

Holiday Inn Louisville Downtown by IHG

10/10 Excellent
"No commo"
Ed 5-night trip
Posted 2 days ago
Holiday Inn Louisville Downtown by IHG
Louisville Marriott Downtown

Louisville Marriott Downtown

8/10 Good
"Didn’t like the many homeless people right outside on the sidewalk."
Paul 3-night trip
Posted 2 days ago
Louisville Marriott Downtown
Econo Lodge Louisville Downtown

Econo Lodge Louisville Downtown

10/10 Excellent
"Clean. Staff were friendy."
Candace 1-night trip
Posted 5 days ago
Econo Lodge Louisville Downtown
The Reserve on Main

The Reserve on Main

10/10 Excellent
"All good."
Jason 2-night trip
Posted 5 days ago
The Reserve on Main

Other attractions near Louisville Science Center

A tall wooden baseball bat leaning against a brick building with a sign reading "Hillerich & Brassler Co."

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
See properties
A modern building with a cylindrical structure and a glass facade.

Muhammad Ali Center

8.8/10 (295 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
See properties
The Frazier History Museum with red doors and a tree in front.

Frazier International History Museum

9.4/10 (10 reviews)
Get to know Louisville with a visit to this esteemed museum. It’s a great spot for social interaction as well.
See properties
The Kentucky Center for the Performing Arts building facade with large glass windows and a prominent sign.

Kentucky Center for the Performing Arts

8.8/10 (49 reviews)
Enjoy a pleasant night at the opera or attend a concert, live dance or stage production at this glass-fronted venue in downtown Louisville.
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Kentucky Museum of Art and Craft

You can spend an afternoon exploring the galleries in Kentucky Museum of Art and Craft during your travels in Louisville. Stroll along the area's riverfront or experience its lively festivals.
See properties

Golden Statue of David

Find out about the history of Louisville when you take a trip to Golden Statue of David. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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SAR Genealogical Research Library: NSSAR Library

You can spend an afternoon browsing the exhibits at SAR Genealogical Research Library: NSSAR Library in Louisville. Amble around this family-friendly area's riverfront and enjoy its top-notch restaurants.
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Louisville Glassworks

You can spend an afternoon studying the exhibits at Louisville Glassworks in Louisville. Experience the area's lively festivals or attend a sporting event.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its beautiful river views, sporting events, and great live music scene. If you're looking for a convenient place to stay, check out the 292 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and a 24-hour fitness center. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 292 hotels and other accommodations within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to review the best deals near Louisville Science Center.
Where can I learn more about changing or cancelling my trip in the area near Louisville Science Center?
For more details about picking new dates or cancelling your stay near Louisville Science Center, click here.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum, and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row, and Big Four Bridge. You can catch a show at Louisville Palace, Derby Dinner Playhouse, and Headliners Music Hall.