The Best Hotels Closest to Mayo Clinic Scottsdale in Phoenix for 2026

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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale

louis

₩129,663

₩147,777 total

includes taxes & fees

Nov 22 - Nov 23

A cluster of modern, multi-story buildings with a river in the foreground.

A dining area with a glass table, wooden chairs, and potted plants.

An outdoor patio with a stone wall, wooden pergola, and a cactus.

A golf course with a pond, a clubhouse, and a hilly backdrop.

2. Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale

Stephanie

₩169,143

₩193,110 total

includes taxes & fees

Oct 28 - Oct 29

A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

A reception area with a stone wall, a wooden reception desk, and a modern elevator.

A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

3. Comfort Suites Scottsdale Talking Stick Entertainment District

9.6 km from Mayo Clinic Scottsdale

LAURA

₩144,085

₩164,287 total

includes taxes & fees

Nov 1 - Nov 2

A modern hotel with a brick facade, large windows, and a covered entrance area.

A modern bar area with a wooden ceiling, bar stools, and a counter with a digital screen.

A hotel room with a desk, two beds, a TV, and a large window.

A modern lobby with a sectional sofa, a round coffee table, and a mural on the wall.

4. Springhill Suites Phoenix Scottsdale Marriott

18.2 km from Mayo Clinic Scottsdale

Lucinda

₩144,852

₩165,087 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

A modern lobby with a seating area, a kitchen, and a reception desk.

A modern living room with a sectional sofa, orange ottomans, a dining area, and a kitchen with a stone accent wall.

A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.

5. Home2 Suites by Hilton Mesa Longbow, AZ

14.8 km from Mayo Clinic Scottsdale

Claudia

₩184,439

₩210,758 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a reception desk, seating area, and a large wall mural.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale

Joseph

₩116,961

₩133,300 total

includes taxes & fees

Oct 26 - Oct 27

A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.

A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

A bar area with a long counter, multiple stools, and overhead pendant lighting.

7. Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale

Deborah

₩178,617

₩203,570 total

includes taxes & fees

Nov 15 - Nov 16

A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.

A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.

A modern hotel with a covered entrance, multiple floors, and a parking lot.

8. Hyatt Place Phoenix/Mesa

17.8 km from Mayo Clinic Scottsdale

Laura

₩178,617

₩204,107 total

includes taxes & fees

Nov 22 - Nov 23

A modern infinity pool with a view of mountains and a sunset.

A poolside lounge with a view of a hotel building, a TV, and a bar area with a bottle of champagne.

An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.

A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

9. Talking Stick Resort

8.8 km from Mayo Clinic Scottsdale

Jessica

₩210,781

₩278,055 total

includes taxes & fees

Nov 22 - Nov 23

A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

A bar area with a bar counter, multiple chairs, and a sofa.

A restaurant setting with round tables, chairs, and empty wine glasses.

A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.

10. Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale

Marie

₩135,365

₩154,275 total

includes taxes & fees

Oct 27 - Oct 28

A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

A bar area with multiple seating options, a bar counter, and a television screen displaying sports.

An outdoor seating area with a fire feature, surrounded by a fence and palm trees, under a sunset sky.

A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

11. Embassy Suites by Hilton Phoenix Scottsdale

17.8 km from Mayo Clinic Scottsdale

Matthew

₩194,203

₩219,585 total

includes taxes & fees

Nov 22 - Nov 23

A spacious living area with a kitchen, modern furniture, and a fireplace.

A modern lobby with a pool view, orange seating, and a wooden accent wall.

A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.

12. Fountain Park Hotel, BW Signature Collection

7.3 km from Mayo Clinic Scottsdale

Guadalupe

₩141,716

₩161,797 total

includes taxes & fees

Oct 26 - Oct 27

A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

A hotel reception area with a wooden reception desk, a green carpet, and a yellow kiosk with snacks.

A modern office space with multiple desks, chairs, and a meeting area.

A hotel room with two beds, a desk, a TV, and a balcony with a view.

13. Spark by Hilton Fountain Hills Scottsdale

7.6 km from Mayo Clinic Scottsdale

Herbert M Beatty

₩107,408

₩122,626 total

includes taxes & fees

Nov 3 - Nov 4

A hotel with a curved entrance, a flagpole, and palm trees.

A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.

An outdoor patio area with multiple tables and chairs, a barbecue grill, and a view of a building with large windows.

A hotel reception desk with a sign for the Sundry Shop and Holiday Inn Express.

14. Holiday Inn Express Scottsdale North by IHG

Central Scottsdale, 12 km from Mayo Clinic Scottsdale

Melanie

₩129,663

₩147,778 total

includes taxes & fees

Nov 23 - Nov 24

A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.

An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

A hotel pool area with multiple lounge chairs, a small pool, and a building with a sign.

A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".

15. Tru By Hilton Scottsdale Salt River

8.9 km from Mayo Clinic Scottsdale

Colleen

₩150,700

₩171,828 total

includes taxes & fees

Nov 8 - Nov 9

A hotel dining area with a table and chairs, patterned curtains, and a view through large windows.

A hotel room with a large window, a desk, a bed, a TV, and a chair.

A golf course with sand bunkers, a flagstick, and mountains in the background.

A hotel lobby with a bar area, seating, and a reception desk.

16. Hampton Inn & Suites Scottsdale at Talking Stick

9.1 km from Mayo Clinic Scottsdale

Cynthia

₩156,323

₩178,240 total

includes taxes & fees

Nov 22 - Nov 23

A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

A modern hotel lobby with multiple seating areas, a reception desk, and a large flat-screen TV mounted on the wall.

A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered seating area.

17. SpringHill Suites Scottsdale North

13.8 km from Mayo Clinic Scottsdale

Charlene

₩156,323

₩176,755 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

A bar area with a long counter, multiple bar stools, and overhead lighting.

A hotel room with two beds, a desk, a sofa, and a TV.

A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.

18. Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale

Ted

₩213,017

₩242,776 total

includes taxes & fees

Nov 22 - Nov 23

A landscaped garden with a fountain, palm trees, and a building with a red roof.

A pool area with a rock formation, palm trees, and lounge chairs.

A modern kitchen with a glass dining table, bar stools, and a built-in island with a microwave and oven.

A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.

19. Westgate Painted Mountain Golf Resort

17.4 km from Mayo Clinic Scottsdale

Curtis

₩132,711

₩151,647 total

includes taxes & fees

Oct 29 - Oct 30

A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.

A patio area with wicker furniture, a large umbrella, and a pool in the background.

A hotel room with two beds, a nightstand, a lamp, and framed pictures on the wall.

A hotel reception area with a reception desk, a large mirror, framed pictures on the wall, a potted plant, and a welcome mat.

20. Sleep Inn North Scottsdale near Mayo Clinic

Paradise Valley Village, 13.5 km from Mayo Clinic Scottsdale

Margret

₩145,077

₩164,038 total

includes taxes & fees

Nov 22 - Nov 23

View all properties

Compare top hotels near Mayo Clinic Scottsdale

Sonesta Select Scottsdale at Mayo Clinic Campus 0.3 km from Mayo Clinic Scottsdale View	Inn at Eagle Mountain 3.1 km from Mayo Clinic Scottsdale View	Comfort Suites Scottsdale Talking Stick Entertainment District 9.6 km from Mayo Clinic Scottsdale View	Springhill Suites Phoenix Scottsdale Marriott 18.2 km from Mayo Clinic Scottsdale View	Home2 Suites by Hilton Mesa Longbow, AZ 14.8 km from Mayo Clinic Scottsdale View
8.4 Very good 1,093 reviews	9.0 Wonderful 1,036 reviews	9.2 Wonderful 2,059 reviews	9.4 Exceptional 457 reviews	9.6 Exceptional 921 reviews
₩129,663 ₩147,777 total includes taxes & fees Nov 22 - Nov 23	₩169,143 ₩193,110 total includes taxes & fees Oct 28 - Oct 29	₩144,085 ₩164,287 total includes taxes & fees Nov 1 - Nov 2	₩144,852 ₩165,087 total includes taxes & fees Nov 22 - Nov 23	₩184,439 ₩210,758 total includes taxes & fees Nov 22 - Nov 23

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

10/10 Excellent

"Our room was lovely, pools were beautiful with lots of chairs and towels, restaurant was great! We loved the star gazing activity."

Talking Stick Resort

8/10 Good

"The resort was short staffed making getting good service difficult. Luis out at the main pool was amazing and made us feel special. The room was amazing. Was looking forward to sitting out by the fire pits at night but they were never lit and even after asking one night no one showed up to light them. The slot machines very tight seemed like no one was winning on them. Golf course was in great condition but expensive. Resort was very clean with decently priced drinks."

Aiden by Best Western Scottsdale North

10/10 Excellent

"Clean and spacious room"

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent

"Very convenient and enjoyable location"

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent

"Location is wonderful for appointments I have with Mayo Clinic or hospital"

Inn at Eagle Mountain

8/10 Good

"I think I was able to get one of the last rooms same day....beautiful room, comfortable and spacious, bathroom as well. My view was the parking lot, but next time I will book in advance for hopefully a valley view. Friendly young front desk rep offering wine tasting at that time."

Sonesta Simply Suites Phoenix Scottsdale

10/10 Excellent

"Great price! It was actually a suitet with a kitchenette although I didn't use it. I would definitely stay there again if I was in the area!"

Spark by Hilton Fountain Hills Scottsdale

8/10 Good

"Excellent value for a traveler."

Holiday Inn & Suites Scottsdale North - Airpark by IHG

10/10 Excellent

"Wonderful personnel, clean environment and easy access to restaurants etc. The only down was the towels were very scratchy. The free Lyft was so convenient and easy to use. I really enjoyed my week."

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.

Find hotels near Mayo Clinic Scottsdale, Phoenix from ₩122,626

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Our top choices for Mayo Clinic Scottsdale hotels

1. Sonesta Select Scottsdale at Mayo Clinic Campus

2. Inn at Eagle Mountain

3. Comfort Suites Scottsdale Talking Stick Entertainment District

4. Springhill Suites Phoenix Scottsdale Marriott

5. Home2 Suites by Hilton Mesa Longbow, AZ

6. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

7. Hyatt House North Scottsdale

8. Hyatt Place Phoenix/Mesa

9. Talking Stick Resort

10. Aiden by Best Western Scottsdale North

11. Embassy Suites by Hilton Phoenix Scottsdale

12. Fountain Park Hotel, BW Signature Collection

13. Spark by Hilton Fountain Hills Scottsdale

14. Holiday Inn Express Scottsdale North by IHG

15. Tru By Hilton Scottsdale Salt River

16. Hampton Inn & Suites Scottsdale at Talking Stick

17. SpringHill Suites Scottsdale North

18. Hyatt Place Scottsdale - North

19. Westgate Painted Mountain Golf Resort

20. Sleep Inn North Scottsdale near Mayo Clinic

Compare top hotels near Mayo Clinic Scottsdale

Sonesta Select Scottsdale at Mayo Clinic Campus

Inn at Eagle Mountain

Comfort Suites Scottsdale Talking Stick Entertainment District

Springhill Suites Phoenix Scottsdale Marriott

Home2 Suites by Hilton Mesa Longbow, AZ

Top Mayo Clinic Scottsdale Hotel Reviews

ADERO Scottsdale Resort, Autograph Collection

Talking Stick Resort

Aiden by Best Western Scottsdale North

Staybridge Suites Scottsdale - Talking Stick by IHG

Sonesta Select Scottsdale at Mayo Clinic Campus

Inn at Eagle Mountain

Sonesta Simply Suites Phoenix Scottsdale

Spark by Hilton Fountain Hills Scottsdale

Holiday Inn & Suites Scottsdale North - Airpark by IHG

Frequently asked questions