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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.
A dining area with a glass table, wooden chairs, and potted plants.
A golf course with a pond, a clubhouse, and a hilly backdrop.
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

1. Inn at Eagle Mountain

Inn at Eagle Mountain
3.1 km from Mayo Clinic Scottsdale
United States
Shelby
₩160,831
₩183,621 total
includes taxes & fees
Oct 14 - Oct 15
Inn at Eagle Mountain
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.
Lobby lounge
A breakfast buffet area with various pastries and a sign indicating the price of a cheese danish.
A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
0.3 km from Mayo Clinic Scottsdale
United States
Michael
₩119,283
₩135,947 total
includes taxes & fees
Oct 18 - Oct 19
Sonesta Select Scottsdale at Mayo Clinic Campus
A hotel lobby with a reception desk, seating area, and a large wall mural.
A hotel room with two beds, a desk, a lamp, and a window with curtains.
A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.
A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

3. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
United States
Paul
₩112,783
₩128,544 total
includes taxes & fees
Oct 25 - Oct 26
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
A reception area with a stone wall, a wooden reception desk, and a modern elevator.
A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.
A modern hotel lobby with a central bar area, seating arrangements, and a clean, contemporary design.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
9.6 km from Mayo Clinic Scottsdale
United States
LAURA
₩145,360
₩165,740 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Scottsdale Talking Stick Entertainment District
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.
A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.
A modern lobby with a brick wall, seating area, and a flat-screen TV.
A restaurant with multiple round tables and bar stools, a self-service beverage dispenser, and a television mounted on the wall.

5. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
17.8 km from Mayo Clinic Scottsdale
United States
greg
₩180,198
₩205,912 total
includes taxes & fees
Oct 19 - Oct 20
Hyatt Place Phoenix/Mesa
A wooden door with a glass panel, a doormat, and a small window above it.
A modern kitchen with white cabinets, a built-in oven, and a large window.
A bedroom with a desk, a bed, a ceiling fan, and a window with blinds.
Front of property

6. Close to Hiking! Family-friendly Mesa Retreat

Close to Hiking! Family-friendly Mesa Retreat
13.6 km from Mayo Clinic Scottsdale
₩241,247
₩1,049,424 total
includes taxes & fees
Oct 26 - Oct 27
Close to Hiking! Family-friendly Mesa Retreat
An outdoor dining table set with chairs, string lights, and a sunset view.
A modern kitchen area with a dining table and chairs, a stone accent wall, and various kitchen appliances and storage cabinets.
A multi-story hotel with a prominent entrance, large windows, and a well-lit facade.
A modern lobby with a seating area, a kitchen, and a reception desk.

7. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
14.8 km from Mayo Clinic Scottsdale
United States
Damon
₩207,628
₩237,257 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton Mesa Longbow, AZ
A spacious living area with a kitchen, modern furniture, and a fireplace.
A modern lobby with a pool view, orange seating, and a wooden accent wall.
A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.
A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.

8. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
7.3 km from Mayo Clinic Scottsdale
United States
Guadalupe
₩146,088
₩166,795 total
includes taxes & fees
Oct 14 - Oct 15
Fountain Park Hotel, BW Signature Collection
A hotel room with two beds, a TV, a desk, and a window with a view.
A hotel room with two beds, a desk, a TV, and a balcony with a view.
A pool area with a clear blue pool, lounge chairs, and a multi-story building with balconies.
A modern office space with multiple desks, chairs, and a meeting area.

9. Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale
7.6 km from Mayo Clinic Scottsdale
United States
Herlyn
₩119,792
₩136,766 total
includes taxes & fees
Oct 19 - Oct 20
Spark by Hilton Fountain Hills Scottsdale
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.
A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.
A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

10. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
8.7 km from Mayo Clinic Scottsdale
₩137,122
₩156,277 total
includes taxes & fees
Oct 19 - Oct 20
Aiden by Best Western Scottsdale North
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.
A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.
A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.
A multi-story hotel with a central courtyard, parking, and a mountainous backdrop.

11. Hyatt House North Scottsdale

Hyatt House North Scottsdale
14.1 km from Mayo Clinic Scottsdale
United States
Slyqavious
₩180,198
₩205,371 total
includes taxes & fees
Nov 1 - Nov 2
Hyatt House North Scottsdale
A landscaped garden with a fountain, palm trees, and a building with a red roof.
A pool area with a rock formation, palm trees, and lounge chairs.
A tranquil pond with a fountain, surrounded by lush greenery and a large building in the background.
A courtyard with palm trees, a fountain, and a bench.

12. Westgate Painted Mountain Golf Resort

Westgate Painted Mountain Golf Resort
17.4 km from Mayo Clinic Scottsdale
United States
Tammie
₩136,098
₩155,511 total
includes taxes & fees
Nov 1 - Nov 2
Westgate Painted Mountain Golf Resort
A modern infinity pool with a view of mountains and a sunset.
A restaurant with high tables and booths, floral wall decorations, and a view of the mountains.
An outdoor seating area with fire pits and lounge chairs, surrounded by trees and a building with illuminated windows in the background.
A modern bar area with a unique ceiling design, a bar counter with multiple screens, and a patterned carpet.

13. Talking Stick Resort

Talking Stick Resort
8.8 km from Mayo Clinic Scottsdale
Canada
Meghan Rebbecca
₩284,644
₩362,762 total
includes taxes & fees
Nov 8 - Nov 9
Talking Stick Resort
An outdoor patio area with stone pillars, a fire pit, and seating arrangements.
A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.
A lounge area with a grand piano, blue seating, and a stone wall.
A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.

14. Wekopa Casino Resort

Wekopa Casino Resort
10.3 km from Mayo Clinic Scottsdale
United States
jennifer
₩184,741
₩250,669 total
includes taxes & fees
Oct 20 - Oct 21
Wekopa Casino Resort
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.
A spacious hotel lobby with a reception desk, seating areas, and a view of the dining and kitchen areas.
A bar area with multiple seating options, a bar counter, and a television screen displaying sports.
A multi-story hotel with a flat roof and balconies, surrounded by well-maintained grass and trees.

15. Embassy Suites by Hilton Phoenix Scottsdale

Embassy Suites by Hilton Phoenix Scottsdale
17.8 km from Mayo Clinic Scottsdale
United States
Jack
₩207,713
₩234,862 total
includes taxes & fees
Oct 25 - Oct 26
Embassy Suites by Hilton Phoenix Scottsdale
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.
An outdoor patio with a grill, table, and chairs.
A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.
A reception area with a counter, two armchairs, and a round table.

16. Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
14 km from Mayo Clinic Scottsdale
United States
Eriel
₩159,491
₩181,773 total
includes taxes & fees
Oct 25 - Oct 26
Sonesta ES Suites Scottsdale Paradise Valley
A hotel room with a large bed, a dining table with chairs, a sofa, a television, and a kitchenette.
A hotel gym with dumbbells on racks, a bench, and a mirror.
A hotel breakfast area with a self-serve station, seating, and a trash bin.
A hotel room with a desk, chair, television, lamp, and a framed artwork on the wall.

17. Holiday Inn Express Scottsdale North by IHG

Holiday Inn Express Scottsdale North by IHG
Central Scottsdale, 12 km from Mayo Clinic Scottsdale
United States
Linnette
₩140,727
₩160,387 total
includes taxes & fees
Oct 26 - Oct 27
Holiday Inn Express Scottsdale North by IHG
A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.
An outdoor patio area with stone pillars, fire pit seating, and tables.
A swimming pool with lounge chairs and palm trees, surrounded by a building with multiple windows and a covered patio area.
A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

18. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale
United States
Dana
₩216,705
₩246,978 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".
A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.
A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.
An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

19. Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River
8.9 km from Mayo Clinic Scottsdale
United States
Colleen
₩153,795
₩175,357 total
includes taxes & fees
Nov 8 - Nov 9
Tru By Hilton Scottsdale Salt River
A resort with multiple buildings, a large pool area, and surrounding mountains.
A dining area with a table set for six, overlooking a scenic landscape.
A dining area with a table and chairs, a view of a cityscape, and decorative wall panels.
Three people in a swimming pool with rocks and a red umbrella in the background.

20. ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection
3.6 km from Mayo Clinic Scottsdale
United States
Garrett
₩285,877
₩379,950 total
includes taxes & fees
Oct 14 - Oct 15
ADERO Scottsdale Resort, Autograph Collection
View all properties

Compare popular hotels close to Mayo Clinic Scottsdale

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A cluster of modern, multi-story buildings with a river in the foreground.
Inn at Eagle Mountain
9.0
Wonderful
1,028 reviews
View
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.
Sonesta Select Scottsdale at Mayo Clinic Campus
8.4
Very good
1,086 reviews
View
A hotel lobby with a reception desk, seating area, and a large wall mural.
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
8.8
Excellent
1,862 reviews
View
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
Comfort Suites Scottsdale Talking Stick Entertainment District
9.2
Wonderful
2,054 reviews
View
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.
Hyatt Place Phoenix/Mesa
9.2
Wonderful
2,011 reviews
View

Top Mayo Clinic Scottsdale Hotel Reviews

Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent
"Exceeded my expectations. Stayed at a resort close by and this hotel was far better in every aspect. Clean modern rooms very comfortable beds and the breakfast was great. Attentive staff. Restrooms and towels were clean and bleached! Would stay here again."
Alizah 1-night trip
Posted 1 hour ago
Comfort Suites Scottsdale Talking Stick Entertainment District
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

10/10 Excellent
"It was great, in every way!"
Shannon 3-night trip
Posted 1 hour ago
Aiden by Best Western Scottsdale North
Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection

8/10 Good
"The property location is beautiful overlooking fountain park. The location was well kept; the pool was clean and inviting. Staff was friendly and helpful. You do need to be careful in the night we saw a pack of Javalinas, they were around 20. the only thing I have a complaint is the breakfast hours. The breakfast is in a room where they keep lock and the hours are 7am-9am, would of appreciated if they were earlier in morning. Had various appt that made it difficult to partake. And in the rooms, there is coffee but no tea bags."
Berenice 3-night trip
Posted 3 hours ago
Fountain Park Hotel, BW Signature Collection
Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Resort was very clean and rooms were spacious"
Chris 2-night trip
Posted 6 hours ago
Talking Stick Resort
Wekopa Casino Resort

Wekopa Casino Resort

10/10 Excellent
"The hotel staff was very accommodating and helped us check in a little early as we had spa appointments. The beds were comfortable. The room is spacious. The bathroom products have a slight scent that was very pleasing and not overwhelming. There are numerous places to eat - from grab and go to a fine dining restaurant. We had dinner and breakfast in the new Sports Entertainment restaurant, and both meals were very good. This was great for a "staycation" - spa treatments, meal, bingo and gambling. It was raining so we did not try the pool, but it looked inviting."
Cynthia 1-night trip
Posted 6 hours ago
Wekopa Casino Resort
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent
"I stay there at least once a year when I return for medical check up Sometimes twice a year"
Mary Denise 1-night trip
Posted 20 hours ago
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Hampton Inn & Suites Scottsdale at Talking Stick

Hampton Inn & Suites Scottsdale at Talking Stick

10/10 Excellent
"Love it here super clean and friendly. especially the white guy at night he was supper nice and helpful."
Lucianna 1-night trip
Posted 2 days ago
Hampton Inn & Suites Scottsdale at Talking Stick
Inn at Eagle Mountain

Inn at Eagle Mountain

10/10 Excellent
"Wonderful staff!!"
Richard 2-night trip
Posted 3 days ago
Inn at Eagle Mountain

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I be able to find close to Mayo Clinic Scottsdale?
Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.