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Our top choices for Mayo Clinic Scottsdale hotels

A cluster of modern, multi-story buildings with a river in the foreground.
A golf course with a pond, a clubhouse, and a hilly backdrop.
A dining area with a glass table, wooden chairs, and potted plants.
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

1. Inn at Eagle Mountain

Inn at Eagle Mountain
3.1 km from Mayo Clinic Scottsdale
United States
Stephanie
₩170,626
₩194,803 total
includes taxes & fees
Oct 26 - Oct 27
Inn at Eagle Mountain
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.
A hotel courtyard with a paved walkway, palm trees, and a building with multiple balconies and a glass facade.
Lobby lounge
A modern living room with a fireplace, a large flat-screen TV, and comfortable seating.

2. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
0.3 km from Mayo Clinic Scottsdale
United States
louis
₩129,899
₩148,046 total
includes taxes & fees
Nov 22 - Nov 23
Sonesta Select Scottsdale at Mayo Clinic Campus
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.
A reception area with marble reception desks, a wooden ceiling, and a wall-mounted refrigerator.
A spacious living area with a sofa, chairs, a coffee table, and a TV mounted on the wall.
A bar area with a long counter, multiple stools, and overhead pendant lighting.

3. Hyatt House North Scottsdale

Hyatt House North Scottsdale
14.1 km from Mayo Clinic Scottsdale
United States
Deborah
₩178,943
₩203,941 total
includes taxes & fees
Nov 23 - Nov 24
Hyatt House North Scottsdale
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.
A hotel room with two beds, a desk, a sofa, and a TV.
A spacious living area with a sofa, armchairs, and a coffee table. There is a TV mounted on the wall and a balcony with outdoor seating.
A multi-story hotel with a parking lot and a road leading to a roundabout.

4. Hyatt Place Scottsdale - North

Hyatt Place Scottsdale - North
14.1 km from Mayo Clinic Scottsdale
United States
Ted
₩213,406
₩243,218 total
includes taxes & fees
Nov 22 - Nov 23
Hyatt Place Scottsdale - North
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.
A swimming pool with a tiled edge, lounge chairs, and a fitness area with treadmills and exercise equipment.
A modern hotel lobby with a reception desk, marble counter, and a seating area with tables and chairs.
A modern hotel lobby with a bar area, seating, a coffee machine, and a TV.

5. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
8.7 km from Mayo Clinic Scottsdale
United States
Marie
₩135,612
₩154,558 total
includes taxes & fees
Oct 28 - Oct 29
Aiden by Best Western Scottsdale North
An outdoor patio area with stone pillars, a fire pit, and seating arrangements.
A dining area with a large table set for six, surrounded by chairs, with a view of cacti and a stone wall outside.
A historic building with arched entrances and a bell tower, surrounded by cacti and desert landscaping.
A golf course with a mountain backdrop, surrounded by desert vegetation.

6. Wekopa Casino Resort

Wekopa Casino Resort
10.3 km from Mayo Clinic Scottsdale
United States
Linda
₩154,355
₩215,641 total
includes taxes & fees
Oct 25 - Oct 26
Wekopa Casino Resort
A hotel room with two beds, a desk with a chair, a TV, and a lamp.
Pool
A reception area with a stone wall, a wooden reception desk, and a modern elevator.
A modern hotel lobby with a fireplace, seating area, kitchen, and a large TV.

7. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
9.6 km from Mayo Clinic Scottsdale
United States
LAURA
₩144,347
₩164,584 total
includes taxes & fees
Nov 1 - Nov 2
Comfort Suites Scottsdale Talking Stick Entertainment District
A hotel lobby with a reception desk, seating area, and a large wall mural.
A hotel room with a sofa, a TV, a desk, and a chair. There are framed pictures on the wall.
A hotel room with two beds, a desk, a lamp, and a window with curtains.
A hotel lobby with multiple seating areas, a reception desk, and a kitchen in the background.

8. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
United States
Joseph
₩117,226
₩133,603 total
includes taxes & fees
Oct 26 - Oct 27
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.
A modern breakfast area with a counter displaying various food items and a sign reading "TOP IT BREAKFAST".
A hotel room with two beds, a desk, a chair, a window with a view, and a storage sign.
An outdoor patio with round tables and white wicker chairs, red umbrellas, and a brick building in the background.

9. Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River
8.9 km from Mayo Clinic Scottsdale
United States
Colleen
₩150,974
₩172,140 total
includes taxes & fees
Nov 23 - Nov 24
Tru By Hilton Scottsdale Salt River
A hotel pool area with lounge chairs, a hot tub, and a building with balconies.
A motel with a prominent '6' sign, a parking lot, and palm trees.
A hotel room with a bed, a desk, a chair, and a mirror.
A hotel reception area with a modern design, including a reception desk, a television mounted on the wall, and a large window providing natural light.

10. Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square
Fashion Square, 15.9 km from Mayo Clinic Scottsdale
United States
Deborah
₩106,013
₩120,832 total
includes taxes & fees
Nov 23 - Nov 24
Motel 6 Old town Scottsdale/Fashion Square
A swimming pool with a water slide, a sun lounger, and a covered seating area.
A reception area with a blue counter, a television screen, and a modern interior design.
A Holiday Inn & Suites building with a curved facade, multiple balconies, and a well-lit entrance.
A hotel room with a sofa, a chair, a desk with a television, a lamp, and a framed artwork on the wall.

11. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Holiday Inn & Suites Scottsdale North - Airpark by IHG
9.7 km from Mayo Clinic Scottsdale
United States
Ally Marie
₩157,735
₩179,770 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn & Suites Scottsdale North - Airpark by IHG
A spacious living area with a kitchen, modern furniture, and a fireplace.
A modern kitchen with blue cabinets, a stainless steel refrigerator, and a white countertop.
A spacious lobby with a high ceiling, modern chandeliers, a fire feature, and a large TV screen.
A hotel room with a large bed, a dresser with drawers, a wardrobe, and a wall-mounted TV displaying a pool view.

12. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
7.3 km from Mayo Clinic Scottsdale
United States
Guadalupe
₩157,735
₩180,086 total
includes taxes & fees
Oct 28 - Oct 29
Fountain Park Hotel, BW Signature Collection
An outdoor lounge area with white sofas, a fire pit, and a pool in the background.
A modern kitchen with a bar area, bar stools, and a dining table with chairs.
A modern hotel lobby with a long seating area, a reception desk, and large windows providing natural light.
A modern outdoor lounge area with white furniture, a pool, and large umbrellas.

13. AC Hotel by Marriott Scottsdale North

AC Hotel by Marriott Scottsdale North
Paradise Valley Village, 13.4 km from Mayo Clinic Scottsdale
United States
Laura
₩190,580
₩215,488 total
includes taxes & fees
Nov 22 - Nov 23
AC Hotel by Marriott Scottsdale North
A swimming pool with lounge chairs and a covered seating area, surrounded by palm trees and a building with multiple windows.
A hotel room with two beds, a TV, a desk, a chair, and a view of palm trees.
A modern lobby with a brick wall, seating area, and a flat-screen TV.
A modern hotel with a covered entrance, multiple floors, and a parking lot.

14. Hyatt Place Phoenix/Mesa

Hyatt Place Phoenix/Mesa
17.8 km from Mayo Clinic Scottsdale
United States
Laura
₩178,943
₩204,478 total
includes taxes & fees
Nov 22 - Nov 23
Hyatt Place Phoenix/Mesa
A modern hotel lobby with a long bar area, multiple seating options, and large windows offering views of palm trees and a pool.
A Hampton Inn & Suites with a stone facade, a welcoming entrance, and a clear sky at dusk.
An outdoor patio area with stone pillars, fire pit seating, and tables.
A modern kitchen with dark wooden cabinets, a white countertop, and a black refrigerator.

15. Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard

Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
Central Scottsdale, 12.3 km from Mayo Clinic Scottsdale
United States
Dana
₩188,155
₩214,440 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn & Suites Phoenix/Scottsdale on Shea Boulevard
A spacious lobby with a modern staircase, a comfortable seating area, and a large window providing natural light.
A hotel pool area with two hot tubs and lounge chairs.
A hotel reception area with a reception desk, a large mirror, framed pictures on the wall, a potted plant, and a welcome mat.
A hotel room with two beds, a nightstand, a lamp, and framed pictures on the wall.

16. Sleep Inn North Scottsdale near Mayo Clinic

Sleep Inn North Scottsdale near Mayo Clinic
Paradise Valley Village, 13.5 km from Mayo Clinic Scottsdale
United States
Margret
₩145,341
₩164,337 total
includes taxes & fees
Nov 22 - Nov 23
Sleep Inn North Scottsdale near Mayo Clinic
Lobby
A rooftop terrace with a view of a mountain at sunset, outdoor seating, and a pergola structure.
A cozy restaurant with wooden furniture, hanging light fixtures, and a bar area.
A desert-style building with multiple rooms, surrounded by cacti and shrubs, with a rocky mountain in the background.

17. Four Seasons Resort Scottsdale at Troon North

Four Seasons Resort Scottsdale at Troon North
Troon North, 17.2 km from Mayo Clinic Scottsdale
United States
Robert
₩768,790
₩959,270 total
includes taxes & fees
Nov 23 - Nov 24
Four Seasons Resort Scottsdale at Troon North
A lobby with a stone fireplace, wooden beams, and a chandelier.
An indoor water park with slides, a wave pool, and seating areas.
An indoor adventure park with rope bridges, climbing structures, and a large bear statue.
A modern bar area with a long counter, multiple stools, and a view through large windows.

18. Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
10.2 km from Mayo Clinic Scottsdale
United States
Dejanira
₩210,689
₩246,548 total
includes taxes & fees
Nov 11 - Nov 12
Great Wolf Lodge Arizona
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.
An outdoor patio with a grill, table, and chairs.
A hotel room with a bed, a desk with a TV, a sofa, and a coffee table.
A reception area with a counter, two armchairs, and a round table.

19. Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
14 km from Mayo Clinic Scottsdale
United States
Denine
₩160,386
₩182,793 total
includes taxes & fees
Nov 23 - Nov 24
Sonesta ES Suites Scottsdale Paradise Valley
A hotel pool area with sun loungers, a children's play area, and a building with a sign.
An outdoor patio area with round tables and white wicker chairs, red umbrellas, and potted plants.
A modern hotel lobby with a curved reception desk, seating area with sofas and chairs, and a large wall with a 'HOME2' sign.
A modern kitchen with a central island, bar stools, and a sign that reads "inspired table".

20. Home2 Suites by Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River
9.6 km from Mayo Clinic Scottsdale
United States
Felipe
₩164,123
₩187,133 total
includes taxes & fees
Nov 23 - Nov 24
Home2 Suites by Hilton Scottsdale Salt River
View all properties

Compare top hotels near Mayo Clinic Scottsdale

A cluster of modern, multi-story buildings with a river in the foreground.

Inn at Eagle Mountain

3.1 km from Mayo Clinic Scottsdale
View
A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

Sonesta Select Scottsdale at Mayo Clinic Campus

0.3 km from Mayo Clinic Scottsdale
View
A modern outdoor lounge area with sofas, chairs, and a glass-top coffee table with a fire feature.

Hyatt House North Scottsdale

14.1 km from Mayo Clinic Scottsdale
View
An outdoor seating area with sofas, tables, and umbrellas, featuring a fire feature in the center.

Hyatt Place Scottsdale - North

14.1 km from Mayo Clinic Scottsdale
View
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

Aiden by Best Western Scottsdale North

8.7 km from Mayo Clinic Scottsdale
View
9.0
Wonderful
1,031 reviews
8.4
Very good
1,092 reviews
9.6
Exceptional
1,001 reviews
9.4
Exceptional
1,286 reviews
9.0
Wonderful
1,193 reviews
₩170,626
₩194,803 total
includes taxes & fees
Oct 26 - Oct 27
₩129,899
₩148,046 total
includes taxes & fees
Nov 22 - Nov 23
₩178,943
₩203,941 total
includes taxes & fees
Nov 23 - Nov 24
₩213,406
₩243,218 total
includes taxes & fees
Nov 22 - Nov 23
₩135,612
₩154,558 total
includes taxes & fees
Oct 28 - Oct 29

Top Mayo Clinic Scottsdale Hotel Reviews

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

10/10 Excellent
"Loved every!"
Lindsay 5-night trip
Posted 1 hour ago
Aiden by Best Western Scottsdale North
Wekopa Casino Resort

Wekopa Casino Resort

8/10 Good
"The resort was ok. I liked so much, the only inconvenience was the golf course was closed."
Darío 4-night trip
Posted 1 hour ago
Wekopa Casino Resort
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

10/10 Excellent
"Over all stay was clean and staff was very attentive and helpful. Will definitely be coming back."
Carlos 4-night trip
Posted 3 hours ago
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection

8/10 Good
"The hotel was very nice, I loved the bar and how close my room was towards the entrance. Room service was very slow when I was in need of extra towels. But other than that it was great."
Aure 2-night trip
Posted 3 hours ago
ADERO Scottsdale Resort, Autograph Collection
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

10/10 Excellent
"very clean well appointed helpful staff shuttle was great parking lot could use repaving"
louis 1-night trip
Posted 4 hours ago
Sonesta Select Scottsdale at Mayo Clinic Campus
Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale

8/10 Good
"Excellent value for a traveler."
Herbert M Beatty 1-night trip
Posted 4 hours ago
Spark by Hilton Fountain Hills Scottsdale
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

10/10 Excellent
"Staff was great. Breakfast was amazing."
Arturo 2-night trip
Posted 5 hours ago
Comfort Suites Scottsdale Talking Stick Entertainment District
Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG

10/10 Excellent
"Nice place tho the handicapped rooms weren’t available and we were put far from the elevators"
Katrina 2-night trip
Posted 1 day ago
Staybridge Suites Scottsdale - Talking Stick by IHG
Great Wolf Lodge Arizona

Great Wolf Lodge Arizona

10/10 Excellent
"El mejor hotel para ir con niños es este hay diversión para todas las edades muy bonito todas las instalaciones"
Andres A 2-night trip
Posted 1 day ago
Great Wolf Lodge Arizona

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I be able to find close to Mayo Clinic Scottsdale?
Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.