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Our top choices for Mayo Clinic Scottsdale hotels

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

1. Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
0.3 km from Mayo Clinic Scottsdale
8.4 out of 10, Very good, (1,083 reviews)
"all good happy place to stay"
United States
louis
The price is ₩126,328
₩143,976 total
includes taxes & fees
Nov 22 - Nov 23
Sonesta Select Scottsdale at Mayo Clinic Campus
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

2. Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3.1 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,035 reviews)
"Great place to stay, very roomy"
United States
Jose Jr
The price is ₩209,139
₩238,759 total
includes taxes & fees
Nov 30 - Dec 1
Inn at Eagle Mountain
A modern infinity pool with a view of mountains and a sunset.

3. Talking Stick Resort

Talking Stick Resort
4.0 star property
8.8 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (5,192 reviews)
"I loved staying here!"
United States
Jessica
The price is ₩164,397
₩226,370 total
includes taxes & fees
Dec 10 - Dec 11
Talking Stick Resort
A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

4. Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (2,078 reviews)
"would definitely stay here again"
United States
LAURA
The price is ₩146,352
₩166,871 total
includes taxes & fees
Nov 22 - Nov 23
Comfort Suites Scottsdale Talking Stick Entertainment District
An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

5. Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
4.0 star property
14.8 km from Mayo Clinic Scottsdale
9.6 out of 10, Exceptional, (929 reviews)
"Clean room, nice outdoor pool"
Canada
Claudia
The price is ₩173,633
₩198,410 total
includes taxes & fees
Nov 23 - Nov 24
Home2 Suites by Hilton Mesa Longbow, AZ
A modern kitchen with dark cabinetry, a wooden island, stainless steel appliances, and pendant lighting.

6. Close to Hiking! Family-friendly Mesa Retreat

Close to Hiking! Family-friendly Mesa Retreat
3.0 star property
13.6 km from Mayo Clinic Scottsdale
The price is ₩262,062
₩1,075,316 total
includes taxes & fees
Nov 22 - Nov 23
Close to Hiking! Family-friendly Mesa Retreat
A hotel room with two beds, a television, a desk with a lamp, and artwork on the wall.

7. Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale
2.5 star property
7.6 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (341 reviews)
"Excellent value for a traveler."
United States
Herbert M Beatty
The price is ₩109,099
₩124,559 total
includes taxes & fees
Nov 16 - Nov 17
Spark by Hilton Fountain Hills Scottsdale
A hotel lobby with a reception desk, seating area, and a large wall mural.

8. La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1,908 reviews)
"We had a great stay, Thank you!"
Canada
Saad
The price is ₩137,038
₩156,183 total
includes taxes & fees
Nov 23 - Nov 24
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
A courtyard with outdoor seating and a fire pit, surrounded by a building with multiple windows and doors.

9. Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,219 reviews)
"Nice hotel in nice area. Very clean property. Room was nice and comfortable."
United States
Ryan
The price is ₩132,174
₩150,639 total
includes taxes & fees
Nov 22 - Nov 23
Aiden by Best Western Scottsdale North
A Courtyard by Marriott hotel with a landscaped entrance featuring a small waterfall and rock formations.

10. Courtyard by Marriott Scottsdale North

Courtyard by Marriott Scottsdale North
3.0 star property
13.6 km from Mayo Clinic Scottsdale
8.6 out of 10, Excellent, (1,004 reviews)
"Very nice and cozy hotel. Quiet and family friendly."
United States
wieslaw
The price is ₩119,742
₩135,392 total
includes taxes & fees
Nov 22 - Nov 23
Courtyard by Marriott Scottsdale North
A modern hotel with a flat roof, multiple floors, and a sign indicating 'Springhill Suites'.

11. SpringHill Suites Scottsdale North

SpringHill Suites Scottsdale North
3.0 star property
13.8 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1,000 reviews)
"Great stay. The front desk ladies were so kind."
United States
Charlene
The price is ₩113,090
₩127,869 total
includes taxes & fees
Nov 22 - Nov 23
SpringHill Suites Scottsdale North
An outdoor patio area with stone pillars, a fire pit, and seating arrangements.

12. Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,014 reviews)
"Great stay"
United States
Joshua
The price is ₩181,697
₩247,306 total
includes taxes & fees
Nov 16 - Nov 17
Wekopa Casino Resort
A swimming pool with a bridge structure, surrounded by buildings with outdoor seating and a clear sky.

13. Holiday Inn & Suites Scottsdale North - Airpark by IHG

Holiday Inn & Suites Scottsdale North - Airpark by IHG
3.5 star property
9.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (936 reviews)
"Clean room and helpful staff. Definitely would stay again"
United States
Ally Marie
The price is ₩153,206
₩174,609 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn & Suites Scottsdale North - Airpark by IHG
A spacious lobby with a high ceiling, multiple seating areas, a reception desk, and a television screen.

14. Embassy Suites by Hilton Phoenix Scottsdale

Embassy Suites by Hilton Phoenix Scottsdale
3.5 star property
17.8 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,038 reviews)
"Enjoyed my stay overall everything was great"
United States
Matthew
The price is ₩180,729
₩204,351 total
includes taxes & fees
Nov 22 - Nov 23
Embassy Suites by Hilton Phoenix Scottsdale
An outdoor seating area with fire pit, red Adirondack chairs, and a covered patio with string lights.

15. Home2 Suites by Hilton Scottsdale North

Home2 Suites by Hilton Scottsdale North
3.0 star property
15 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (837 reviews)
"Very nice place conveniently located. Plenty of parking great staff"
United States
Susan
The price is ₩149,644
₩170,549 total
includes taxes & fees
Nov 22 - Nov 23
Home2 Suites by Hilton Scottsdale North
A hotel room with a bed, desk, chair, television, fireplace, and a dining area.

16. Sonesta ES Suites Scottsdale Paradise Valley

Sonesta ES Suites Scottsdale Paradise Valley
3.0 star property
14 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1,007 reviews)
"Friendly staff, good breakfast, dated rooms, clean"
United States
James
The price is ₩149,174
₩170,013 total
includes taxes & fees
Nov 22 - Nov 23
Sonesta ES Suites Scottsdale Paradise Valley
A spacious lobby with a large seating area, a reception desk, and artwork on the walls.

17. Best Western Plus Scottsdale Thunderbird Suites

Best Western Plus Scottsdale Thunderbird Suites
3.0 star property
Thunderbird Industrial Airpark, 12.1 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1,005 reviews)
"All around a great place to stay for the price, thanks again."
United States
Irene
The price is ₩145,895
₩166,276 total
includes taxes & fees
Nov 30 - Dec 1
Best Western Plus Scottsdale Thunderbird Suites
A landscaped garden with a fountain, palm trees, and a building with a red roof.

18. Westgate Painted Mountain Golf Resort

Westgate Painted Mountain Golf Resort
4.0 star property
17.4 km from Mayo Clinic Scottsdale
8.4 out of 10, Very good, (1,006 reviews)
"Loved everything about it!"
United States
Susan
The price is ₩160,301
₩183,175 total
includes taxes & fees
Nov 11 - Nov 12
Westgate Painted Mountain Golf Resort
A hotel with a curved entrance, a flagpole, and palm trees.

19. Holiday Inn Express Scottsdale North by IHG

Holiday Inn Express Scottsdale North by IHG
2.5 star property
Central Scottsdale, 12 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1,002 reviews)
"Very nice. Comfortable beds, clean rooms and great parking."
United States
Amy
The price is ₩135,735
₩154,697 total
includes taxes & fees
Nov 22 - Nov 23
Holiday Inn Express Scottsdale North by IHG
A spacious living area with a kitchen, modern furniture, and a fireplace.

20. Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.3 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1,004 reviews)
"The location to family was perfect. We used the work out facilities and enjoyed many near by restaurants. We've stayed at this property several times throughout the past 15 years. The price point is perfect for our needs."
United States
Laura
The price is ₩159,925
₩182,597 total
includes taxes & fees
Nov 29 - Nov 30
Fountain Park Hotel, BW Signature Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels near Mayo Clinic Scottsdale

A hotel courtyard with a central pathway, potted plants, and a building with multiple balconies and windows.

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
0.3 km from Mayo Clinic Scottsdale
View
A lobby with stone flooring, wooden furniture, a fireplace, and modern lighting fixtures.

Inn at Eagle Mountain

3.5 star property
3.1 km from Mayo Clinic Scottsdale
View
A modern infinity pool with a view of mountains and a sunset.

Talking Stick Resort

4.0 star property
8.8 km from Mayo Clinic Scottsdale
View
A modern dining area with multiple tables and chairs, a fireplace, and a television mounted on the wall.

Comfort Suites Scottsdale Talking Stick Entertainment District

2.5 star property
9.6 km from Mayo Clinic Scottsdale
View
An outdoor patio with two sofas facing a stone fire pit, under a pergola with string lights.

Home2 Suites by Hilton Mesa Longbow, AZ

4.0 star property
14.8 km from Mayo Clinic Scottsdale
View
8.4
Very good
1,083 reviews
9.0
Wonderful
1,035 reviews
9.4
Exceptional
5,192 reviews
9.2
Wonderful
2,078 reviews
9.6
Exceptional
929 reviews
The price is ₩126,328
₩143,976 total
includes taxes & fees
Nov 22 - Nov 23
The price is ₩209,139
₩238,759 total
includes taxes & fees
Nov 30 - Dec 1
The price is ₩164,397
₩226,370 total
includes taxes & fees
Dec 10 - Dec 11
The price is ₩146,352
₩166,871 total
includes taxes & fees
Nov 22 - Nov 23
The price is ₩173,633
₩198,410 total
includes taxes & fees
Nov 23 - Nov 24
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • No WiFi included
  • Yes, Parking

Top Mayo Clinic Scottsdale Hotel Reviews

A motel sign with neon lights spelling 'MOTEL' and a green banner with 'Starline Motel' text.
Starlite Motel

Starlite Motel

Starlite Motel
Central Mesa

10/10 Excellent

Very comfortable and it had everything I needed to make breakfast and get a good night rest.
United States
Virginia
Reviewed October 1, 2026
Starlite Motel

Frequently Asked Questions

What's the area like around Mayo Clinic Scottsdale?

Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Mayo Clinic Scottsdale?

Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.

How many hotels will I be able to find close to Mayo Clinic Scottsdale?

Expedia has 22 hotels and other accommodations within a mile from Mayo Clinic Scottsdale.

If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals close to Mayo Clinic Scottsdale.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Scottsdale?

To access more information about picking new dates or cancelling your stay near Mayo Clinic Scottsdale, go to https://www.expedia.com/service/.

What can I see and do near Mayo Clinic Scottsdale?

You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, Golf Club at Eagle Mountain, or SunRidge Canyon Golf Club are some local sights worth checking out.