Find Luxury Hotels in Mission District, CA

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Check availability on Mission District Luxury Hotels

Tonight
Jan 25 - Jan 26
Tomorrow
Jan 26 - Jan 27
Next weekend
Jan 30 - Feb 1
In two weeks
Feb 6 - Feb 8

Our top choices for Mission District luxury hotels

Lobby sitting area

El Capitan Hotel

El Capitan Hotel
2.0 star property
Mission District
4.6 out of 10, (826 reviews)
"Mission district is amazing for food and nightlife. Stayed here because of that. Made a mistake roaches and bugs in the room. Crackheads in parking lot break on to your car (no security) "
United States
Doug
El Capitan Hotel
Outdoor spa tub

Inn San Francisco

Inn San Francisco
2.5 star property
San Francisco
9.6 out of 10, Exceptional, (587 reviews)
"Great stay. Friendly, accommodating staff, and fantastic breakfast. "
United States
Christine
Inn San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mission District Hotel Reviews

Club Quarters Hotel in San Francisco

Club Quarters Hotel in San Francisco

10/10 Excellent
"Clean room and helpful staff! "
Angelina 1-night trip
Posted 23 hours ago
Club Quarters Hotel in San Francisco

Frequently asked questions

Are you searching for a great accommodation for your luxury trip to Mission District?
Use Expedia to arrange your flight to San Francisco Intl. Airport (SFO) airport or Oakland Intl. Airport (OAK) airport, and then select from a variety of places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can help you find the best luxury hotel experience that Mission District offers. During your visit, you might want to enjoy the bars which Mission District is known for.
What's there to see and do in Mission District?
Take in the sights and attractions that Mission District offers with a visit to SF Armory, SOMA Pilipinas, and Victoria Theatre. If you have spare time during your trip, you might want to make a stop at San Francisco Public Library and Mission San Francisco de Asís.
How can I get around Mission District?
It's easier to get around town comfortably when you know your options. Nearby metro stations include 16th Street Mission Station, 24th Street Mission Station, and Right Of Way/20th St Stop.