The Best Hotels Closest to Museum of Life and Science in Raleigh for 2026

Our top choices for Museum of Life and Science hotels

Hampton Inn & Suites Durham/North I-85

1.4 km from Museum of Life and Science

Ed

₩203,374 total

includes taxes & fees

May 31 - Jun 1

Holiday Inn Express Durham by IHG

2.2 km from Museum of Life and Science

Kathy

₩173,965 total

includes taxes & fees

May 31 - Jun 1

Suite, 1 King Bed with Sofa bed, Non Smoking | Premium bedding, desk, blackout drapes, iron/ironing board

Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.2 km from Museum of Life and Science

Kathy

₩166,896 total

includes taxes & fees

Jun 14 - Jun 15

Red Roof Inn Durham - Duke Univ Medical Center

2.2 km from Museum of Life and Science

Derrick

₩111,074 total

includes taxes & fees

May 31 - Jun 1

Stylish Durham Retreat - Walkable, Sleeps 6

2.8 km from Museum of Life and Science

₩1,099,261 total

includes taxes & fees

Jun 7 - Jun 8

Hilton Garden Inn Durham/University Medical Center

9th Street District, 3.3 km from Museum of Life and Science

Susan

₩252,806 total

includes taxes & fees

May 30 - May 31

Hampton Inn & Suites Durham University Medical Center

4.8 km from Museum of Life and Science

Curtis

₩198,069 total

includes taxes & fees

May 31 - Jun 1

Residence Inn Durham McPherson/Duke University Medical Cntr

Trinity Park, 3.3 km from Museum of Life and Science

Tiffany

₩286,461 total

includes taxes & fees

May 27 - May 28

SpringHill Suites by Marriott Durham City View

4.6 km from Museum of Life and Science

Evelyn

₩213,745 total

includes taxes & fees

May 31 - Jun 1

JB Duke Hotel

5.6 km from Museum of Life and Science

Andrew

₩342,756 total

includes taxes & fees

May 26 - May 27

University Inn Durham next to Duke University Medical Center

4 km from Museum of Life and Science

Thomas

₩200,779 total

includes taxes & fees

May 29 - May 30

The Durham Hotel

Downtown Durham, 3.6 km from Museum of Life and Science

George

₩320,374 total

includes taxes & fees

Jun 7 - Jun 8

Washington Duke Inn & Golf Club

5.9 km from Museum of Life and Science

Jessica

₩344,470 total

includes taxes & fees

May 31 - Jun 1

Aloft by Marriott Durham Downtown

American Tobacco District, 4 km from Museum of Life and Science

Lucas

₩342,749 total

includes taxes & fees

May 25 - May 26

Durham Marriott City Center

Downtown Durham, 3.6 km from Museum of Life and Science

Nancy

₩261,798 total

includes taxes & fees

Jun 22 - Jun 23

AC Hotel Durham

4.9 km from Museum of Life and Science

krishnan

₩256,148 total

includes taxes & fees

May 31 - Jun 1

The Lodge at Duke Medical Center

4 km from Museum of Life and Science

Tracy

₩248,019 total

includes taxes & fees

May 25 - May 26

Hilton Durham near Duke University

5.2 km from Museum of Life and Science

Mary

₩203,495 total

includes taxes & fees

Jun 7 - Jun 8

Courtyard Durham Near Duke University/Downtown

Croasdaile Farm Master, 3.4 km from Museum of Life and Science

Cammy

₩181,537 total

includes taxes & fees

Jun 1 - Jun 2

21c Museum Hotel Durham

Downtown Durham, 3.7 km from Museum of Life and Science

Tara

₩284,284 total

includes taxes & fees

Jun 21 - Jun 22

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Top Museum of Life and Science Hotel Reviews

21c Museum Hotel Durham

10/10 Excellent

"Could use more signs for check in desk cuz that was confusing but it was a beautiful hotel and would stay there again"

Hampton Inn & Suites Durham/North I-85

8/10 Good

"Loved staying here. Did a staycation for my daughter’s birthday. We stayed here specifically because they had an indoor pool, breakfast and a late check out at noon. It allowed us time to have breakfast and not feel rushed out the door. I decided to stay an extra night & the young lady at the front desk was so helpful with booking the extra night. She made sure I rebooked thru the original app so I got a great rate and then made sure we did not have to move rooms. She also made sure housekeeping stopped by to make sure we had everything we needed for the extra night. Will definitely be back"

Courtyard Durham Near Duke University/Downtown

10/10 Excellent

"Spouse and I stayed two nights for a golf tournament. Very convenient and safe feeling location. Some updates in progress, but a little worn in places. Starbucks location in lobby during breakfast hours and associate was very nice, However , with only one person working it, there was some delay in getting breakfast."

Hilton Durham near Duke University

6/10 Okay

"They charge you for parking, which is crazy nickel and diming. Odd rooms, but clean. The duvet had all the fluff clumped up and yellow, so it sat like a lumpy sheet. Water pressure was the usual Hilton low. There is almost NO storage in the room to put your things away. I had to put my clothes in a desk drawer, because that's it. Weird furniture choices included an incredibly heavy, uncomfortable desk chair with no wheels, as well as a weirdly placed dressing bench which they stuck under the TV instead of the foot of the bed."

Hilton Garden Inn Durham/University Medical Center

10/10 Excellent

"We had a short but pleasant visit at this hotel. The premises outside and inside were well maintained. Our room was clean and comfortable. The staff members were helpful and accommodating. The young African American server in the dining room at breakfast was a jewel. With his caring manner, his warmth, his excellent communication skills, and his efficiency, he made each guest feel wecome and special."

Hotels near other Museum of Life and Science attractions

Brightleaf Square

4.8/5 (8 reviews)

You can browse for the perfect souvenirs at Brightleaf Square during your visit to Durham. Discover the lively festivals and stunning cathedral in this family-friendly area.

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Frequently asked questions

What's the area like around Museum of Life and Science?

Museum of Life and Science is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 11 hotels and other accommodations you'll find within a mile.

What's the best place to stay near Museum of Life and Science?

Hampton Inn & Suites Durham/North I-85 is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.8 mi (1.4 km) from Museum of Life and Science. Other good options within 5 miles include Holiday Inn Express Durham by IHG and Courtyard Durham Near Duke University/Downtown.

How many hotels will I find close to Museum of Life and Science?

Expedia has 11 hotels and other accommodations within a mile from Museum of Life and Science.

If I need to cancel the hotel reservation for my stay near Museum of Life and Science, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to view the best deals near Museum of Life and Science.

Where can I learn more about changing or cancelling my trip in the area near Museum of Life and Science?

To access more information about picking new dates or cancelling your stay near Museum of Life and Science, go to https://www.expedia.com/service/.

What can I see and do near Museum of Life and Science?

You'll want to browse the exhibits at Nasher Museum of Art at Duke University and Bennett Place. Explore landmarks like American Tobacco Campus, Cameron Indoor Stadium, and Black Wall Street. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Museum of Life and Science, Raleigh from ₩111,074

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Our top choices for Museum of Life and Science hotels

Hampton Inn & Suites Durham/North I-85

Holiday Inn Express Durham by IHG

Comfort Inn & Suites Durham near Duke University

Red Roof Inn Durham - Duke Univ Medical Center

Stylish Durham Retreat - Walkable, Sleeps 6

Hilton Garden Inn Durham/University Medical Center

Hampton Inn & Suites Durham University Medical Center

Residence Inn Durham McPherson/Duke University Medical Cntr

SpringHill Suites by Marriott Durham City View

JB Duke Hotel

University Inn Durham next to Duke University Medical Center

The Durham Hotel

Washington Duke Inn & Golf Club

Aloft by Marriott Durham Downtown

Durham Marriott City Center

AC Hotel Durham

The Lodge at Duke Medical Center

Hilton Durham near Duke University

Courtyard Durham Near Duke University/Downtown

21c Museum Hotel Durham

Top Museum of Life and Science Hotel Reviews

21c Museum Hotel Durham

Hotels near other Museum of Life and Science attractions

Brightleaf Square

Frequently asked questions