Orangeburg County Vacations & Trips

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Top destinations in Orangeburg County

Aerial of Lake Marion Dam and Santee river in South Carolina providing drinking water, hydro power and recreational activities
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Orangeburg County Hotel Deals

Baymont by Wyndham Santee

Baymont by Wyndham Santee

2.5 out of 5
249 Britain Street Santee SC
Fully refundableReserve now, pay when you stay
The price is ₩119,037 per night from Mar 25 to Mar 26
₩119,037
₩132,133 total
Mar 25 - Mar 26
includes taxes & fees
7.8/10 Good! (1,437 reviews)
The room was dirty, smelly and bugs. Left room within a hour. Asked for a refund which we haven’t received. Booked this room because it said it had a rating of 8. Can’t imagine how it got this rating.Very disappointing!!!

Reviewed on Mar 23, 2026

Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

2.5 out of 5
263 Britain St. and 273 Britain St. Santee SC
Fully refundableReserve now, pay when you stay
The price is ₩178,952 per night from Apr 13 to Apr 14
₩178,952
₩198,637 total
Apr 13 - Apr 14
includes taxes & fees
9.2/10 Wonderful! (769 reviews)
Love staying here. My only complaint is that the room floor has not always been thoroughly cleaned/mopped. Not visibly dirty but my socks show evidence of the floor not being totally clean. We stay here 2-4 times per year. Breakfast is good and staff are always very nice. Love that they allow pets ...

Reviewed on Mar 23, 2026

Tru By Hilton Santee
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 out of 5
I 95 Exit 98 Santee SC
Fully refundableReserve now, pay when you stay
The price is ₩177,090 per night from Apr 13 to Apr 14
₩177,090
₩196,570 total
Apr 13 - Apr 14
includes taxes & fees
8.8/10 Excellent! (1,006 reviews)
N/a

Reviewed on Mar 22, 2026

Best Western Plus Santee Inn
See all 625 properties in Orangeburg County
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an Orangeburg County vacation package cost?
Create unforgettable memories with our Orangeburg County vacation packages, which start from a low . Choose the flights and hotels that suit your style. Then, add on a few sightseeing tours to cap off your unique adventure.
How do I get a cheap travel package to Orangeburg County?
You'll save big if you combine your hotels, car rentals and flights into an Orangeburg County vacation package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer over 550 air carriers and 1,000,000 properties all over the world, which means you'll always have plenty of options to choose from. Like to save even more? Add some popular activities to your package deal to unlock even bigger bargains! After all, travel is about more than just getting to your destination.
What are the top hotels in Orangeburg County?
Take a look at Baymont by Wyndham Santee and Tru by Hilton Orangeburg. They're the first choice for many travelers to Santee. If Orangeburg features on your itinerary, Fairfield Inn & Suites by Marriott Santee and Best Western Plus Santee Inn are two welcoming options.
How far in advance should I book my Orangeburg County vacation?
It can be difficult to know when is the ideal time to book your Orangeburg County vacation. But typically the earlier you book, the better the prices. In some cases, you can book your flights and hotels up to a year before your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable bargains featured on Expedia all the time.
What does an Expedia Orangeburg County travel package include?
It comes down to what you're looking for. If you're traveling by yourself, you might decide to bundle flights and hotels. Taking the entire family to Orangeburg County? A travel package that includes flights, hotels and rental cars might be a better fit. Expedia gives you the flexibility to tailor-make your travel package.
What should I know before booking an Orangeburg County travel package?
When you book your flights, hotels and car rentals together, you'll walk away with great discounts. Whether you're organizing a mountain getaway in a cabin or want to stay in a ritzy city hotel, Expedia will help make it happen.
Can I choose my airline with an Orangeburg County Expedia vacation package?
With a vacation package, you're the boss. Whether you're eager to fly to Orangeburg County in coach or first class, simply pick from the available airline options. Expedia has access to over 550 partner airlines all over the world.
If I'm not able to travel, can I cancel my Orangeburg County vacation package?
You sure can, and we'll help you every step of the way. You may be able to cancel or amend your Orangeburg County vacation package for free if you booked in the last 24 hours. However, you may incur a fee from your hotel, airline or car rental company for older bookings. If life throws you a curveball, have a look at our Customer Service Portal for further information.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.