Find Casinos in Otay Mesa, CA

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check availability on Otay Mesa Casinos

Tonight
Jul 30 - Jul 31
Tomorrow
Jul 31 - Aug 1
This weekend
Aug 1 - Aug 3
Next weekend
Aug 8 - Aug 10

Top Otay Mesa Casinos

Sycuan Casino Resort
3 outdoor pools, cabanas (surcharge), pool umbrellas

Sycuan Casino Resort

4.0 star property
9.2 out of 10, Wonderful, (1441)
"We had a wonderful stay, will definitely visit again!"
The price is ₩160,671
₩193,417 total
includes taxes & fees
Aug 18 - Aug 19
Sycuan Casino Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa Hotel Reviews

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

10/10 Excellent
"I really like this hotel. Breakfast was good and had a lot of options and the rooms were spacious. I really liked that. "
Desiree 3-night trip
Posted 2 days ago
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Frequently asked questions

Searching for casino hotels in Otay Mesa?
Hoping to win big in Otay Mesa? Lucky for you, you'll find Jamul Casino, Caliente Racetrack Casino, and Caliente Casino in the area, plus lots more to see and do. Visitors enjoy the family-friendly activities, beaches, and shopping. You might be interested in the area's popular sights, which include San Diego Zoo, San Ysidro Border Crossing, and Hotel del Coronado.
What's the best place to stay if you'd like to visit the local casinos in Otay Mesa?
Quality Suites San Diego Otay Mesa is a hotel featuring free breakfast and free WiFi, and it's a top choice near the casinos. Another good option near the gaming is Holiday Inn Express Hotel & Suites San Diego Otay Mesa, an IHG Hotel.
What is there to do in Otay Mesa?
You can head to Alameda Otay, Plaza Península Shopping Center, or Plaza Rio Commercial Center to shop for the perfect souvenir. For a chance to experience some culture, you can check out North Island Credit Union Amphitheatre, Centro Cultural Tijuana, or Fronton Jai Alai Palace. Additionally, you might want to add San Diego Zoo and San Ysidro Border Crossing to your itinerary.