Find Cheap Hotels in Otay Mesa, CA

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Our top choices for Otay Mesa cheap hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1564)
"Great place to stay. Really clean and helpful staff "
United States
Zulma
The price is ₩168,728
₩191,928 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.2 out of 10, Good, (1004)
"Beautiful place "
United States
Joe
The price is ₩157,513
₩179,171 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Suites San Diego Otay Mesa

Hyatt Regency Mission Bay Spa and Marina

Hyatt Regency Mission Bay Spa and Marina
4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1582)
"Totally Recommend! Rooms are really clean and comfortable, the staff are great as well. "
United States
Fernando
The price is ₩187,773
₩294,125 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Hyatt Regency Mission Bay Spa and Marina

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
Point Loma
7.4 out of 10, Good, (4119)
"Get location to the airport, safe, great staff, & overall wonderful stay"
United States
Tyler
The price is ₩131,692
₩151,373 total
includes taxes & fees
Dec 25 - Dec 26
Wyndham Garden San Diego Near SeaWorld

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
Downtown San Diego
8.8 out of 10, Excellent, (789)
"would stay again and recommend "
United States
Brendi
The price is ₩165,725
₩192,149 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The DEXTRO Little Italy, BW Premier Collection

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1422)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is ₩166,271
₩191,120 total
includes taxes & fees
Jan 3 - Jan 4, 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2871)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is ₩260,425
₩382,578 total
includes taxes & fees
Dec 25 - Dec 26
Manchester Grand Hyatt San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6021)
"Always an amazing stay"
United States
Jana
The price is ₩199,980
₩274,779 total
includes taxes & fees
Dec 30 - Dec 31
Wyndham San Diego Bayside

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1310)
"Checking in was easy and friendly staff."
United States
Elvira
The price is ₩131,589
₩151,254 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Hampton Inn San Diego/Mission Valley

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
Harbor Island
8.4 out of 10, Very Good, (3169)
"Great stay! "
United States
Melissa
The price is ₩184,961
₩265,872 total
includes taxes & fees
Dec 25 - Dec 26
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What is Otay Mesa like for travelers on a budget?
Discover low cost places to stay in Otay Mesa on Expedia.com and plan a vacation that sticks within your budget. Otay Mesa is a destination that visitors enjoy for its shopping and dining options. You can browse a wide range of accommodation choices with Member Prices to score great deals. Guided by our site's convenient page filters, you can search by price per night, or by favorite amenities like free breakfast and free airport transportation. If you're interested in affordable options near specific attractions, try filtering by location to refine your search. While you browse, use the heart button to keep track of your favorites so that you can return to them easily when you're ready to decide. Interested in a flight or a rental car too? Take your pick of the Bundle and Save vacation packages and discover big savings by reserving transportation at the same time.
What is there to see and do in Otay Mesa?
Otay Mesa is known for its shopping and dining options, and offers plenty to see and do without spending a fortune. You can budget for the popular local attractions that are highest on your list, such as San Diego Zoo and San Ysidro Border Crossing, and choose other low-cost activities to fill your itinerary. If you're looking to enjoy the area's natural beauty, you can get outdoors at Imperial Beach, Silver Strand State Beach, or San Diego Bay.
How can I get to Otay Mesa and get around on a budget?
Checking out these ways to get around Otay Mesa is a smart way to keep your trip affordable. The most convenient airport is 0.9 mi (1.5 km) away from the center in Tijuana Intl. Airport (TIJ). If that doesn't suit your budget, you can book a flight to San Diego Intl. Airport (SAN), located 17.7 mi (28.4 km) away. Otay Mesa might not have very many public transportation choices so renting a car could be a reasonable alternative to explore more of the area.

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