Find hotels in Sanibel Isles, Sanibel

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Our top choices for Sanibel Isles hotels

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
28 km from Sanibel Isles
8.0 out of 10, Very Good, (1507)
"Nice and beautiful place to stay "
United States
Maguenne
The price is ₩107,869
₩120,273 total
includes taxes & fees
Dec 28 - Dec 29
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1041)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is ₩219,637
₩277,110 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Lani Kai Beachfront Resort

Comfort Inn & Suites Fort Myers Airport

Comfort Inn & Suites Fort Myers Airport
2.5 star property
27.7 km from Sanibel Isles
8.8 out of 10, Excellent, (1120)
"Great staff"
United States
Alison
The price is ₩141,659
₩157,949 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites Fort Myers Airport

Trianon Bonita Bay

Trianon Bonita Bay
3.5 star property
27.6 km from Sanibel Isles
9.2 out of 10, Wonderful, (1707)
"Clean personal and Inviting with shopping and in-house restaurants. Beautiful Lake on the property gives it the right feel "
United States
Clarence
The price is ₩206,641
₩230,406 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Trianon Bonita Bay

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
27.6 km from Sanibel Isles
9.6 out of 10, Exceptional, (1000)
"Clean rooms and wonderful breakfast. Appreciated the airport shuttle as well."
United States
Susan
The price is ₩194,944
₩217,362 total
includes taxes & fees
Dec 28 - Dec 29
Holiday Inn Express & Suites Fort Myers Airport by IHG

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3.0 star property
29.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (1230)
"Nice hotel very clean and quiet "
United States
Gustavo
The price is ₩164,988
₩183,962 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

Best Western Fort Myers Waterfront

Best Western Fort Myers Waterfront
3.0 star property
27.5 km from Sanibel Isles
7.4 out of 10, Good, (1001)
"Great spot!!"
United States
barbara
The price is ₩158,338
₩176,547 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Best Western Fort Myers Waterfront

Hilton Garden Inn Ft Myers

Hilton Garden Inn Ft Myers
3.0 star property
19.9 km from Sanibel Isles
8.6 out of 10, Excellent, (1000)
"Great amenities, pool and spa, clean room, beautiful lobby and good on site restaurant "
United States
Aleksandar
The price is ₩161,370
₩179,927 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Hilton Garden Inn Ft Myers

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (1488)
"Excellent value with a great location and a solid staff!"
United States
David
The price is ₩374,004
₩453,115 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Sanibel Island Beach Resort

Courtyard by Marriott Fort Myers Cape Coral

Courtyard by Marriott Fort Myers Cape Coral
3.0 star property
25.2 km from Sanibel Isles
8.2 out of 10, Very Good, (1002)
"Very friendly staff, super comfortable room"
United States
Rocio
The price is ₩154,656
₩172,442 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Courtyard by Marriott Fort Myers Cape Coral

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
23.4 km from Sanibel Isles
7.2 out of 10, Good, (148)
"The service at the front desk was exceptional, the new manager is doing an amazing job!!"
United States
Sandro
The price is ₩107,182
₩119,508 total
includes taxes & fees
Dec 27 - Dec 28
Woodspring Suites Fort Myers - Cape Coral

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1213)
"Nice rooms, great having the bar onsite"
United States
Lee
The price is ₩115,873
₩129,198 total
includes taxes & fees
Dec 29 - Dec 30
Dolphin Key Resort

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
23 km from Sanibel Isles
7.6 out of 10, Good, (199)
"Microwave made an explosion when tried to use it. The rest amazing"
United States
Alain
The price is ₩108,703
₩140,537 total
includes taxes & fees
Dec 27 - Dec 28
Quality Inn Fort Myers Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral
3.0 star property
20.1 km from Sanibel Isles
8.6 out of 10, Excellent, (791)
"A great location. Staff was very helpful. Pool was heated!"
United States
FRED
The price is ₩154,511
₩172,279 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
12.1 km from Sanibel Isles
9.4 out of 10, Exceptional, (1002)
"Great rooms, good staff"
United States
Dedan
The price is ₩198,432
₩221,251 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
21.9 km from Sanibel Isles
7.6 out of 10, Good, (1131)
"Loved it. The staff was great rooms were clean. "
United States
Austin
The price is ₩98,959
₩110,339 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Americas Best Value Inn Ft. Myers

Best Western Fort Myers Inn & Suites

Best Western Fort Myers Inn & Suites
2.5 star property
25.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1116)
"Clean room, old property and fresh, varied options for breakfast"
Canada
supriya
The price is ₩129,068
₩143,911 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Best Western Fort Myers Inn & Suites

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.9 km from Sanibel Isles
8.8 out of 10, Excellent, (1002)
"Great hotel and location and good value. "
United States
Amy
The price is ₩182,352
₩203,323 total
includes taxes & fees
Jan 3 - Jan 4, 2026
Doubletree by Hilton Fort Myers at Bell Tower Shops

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.6 out of 10, Excellent, (1000)
"The property was clean and the breakfast was excellent the staff was friendly and convenient to Sanibel Island"
United States
robert
The price is ₩194,944
₩217,363 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Residence Inn by Marriott Fort Myers Sanibel

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
10.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1002)
"Great Place to Stay!"
United States
JUDY
The price is ₩279,420
₩311,564 total
includes taxes & fees
Dec 28 - Dec 29
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most.

West End

While visiting West End, you might make a stop by sights like J. N. Ding Darling National Wildlife Refuge and Bowman's Beach.

Mid Island

While visiting Mid Island, you might make a stop by sights like Periwinkle Way and Sanibel Island Southern Beach.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

If you're spending some time in Beachview Country Club Estates, Periwinkle Way and Sanibel Island Golf Club are top sights worth seeing.

Sanctuary

While Sanctuary might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travelers to the Sanibel Isles neighborhood in Sanibel will be sure to enjoy their stay.
How many hotels will I find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodations in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and get a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to get the best deals available in Sanibel Isles.
Where can I learn more about changing or cancelling my trip to Sanibel Isles?
To access more information about picking new dates or cancelling your trip to Sanibel Isles, go to https://www.expedia.com/service/.
What is there to do in this Sanibel neighborhood?
Woodring Point, Woodring Beach, and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.