Santa Ana

Panama City

Photo by Isa
Photo by Isa

Popular places to visit

Rainy day in Panama City but the charm of this city never ends. A beautiful rainbow over the city invites us to spend a bright day in paradise. #LifeAtExpedia

Multiplaza Pacific Mall

4.5/5(634 reviews)

During your trip to Panama City, you can enjoy retail therapy at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

4.5/5(456 reviews)

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Avenida Balboa

4/5(554 reviews)

You can find the perfect gifts to bring home at Avenida Balboa during your trip to Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa
This resort is the place to go on the happening Isla Flamenco. Inside you'll find a Duty Free store, a pick & mix candy buffet called Sweet Day, and several restaurants. Not to mention a stunning view of the Flamenco Marina & the Panama City skyline. Did you know that Fort Amador was actually a US army base, built to protect the Panama Canal? When the US pulled out

Fuerte Amador Resort & Marina

Explore the waterfront in Ancon with a trip to Fuerte Amador Resort & Marina. Check out the shops and top-notch restaurants in this vibrant area.

Fuerte Amador Resort & Marina
Panama

Miraflores Locks

4.5/5(783 reviews)

Learn about the local history of Ancon with a stop at Miraflores Locks. Visit the shops and casinos in this vibrant area.

Miraflores Locks
Summer time in Panama City, blue sky and sunny days to enjoy this city. #lifeatexpedia #PanamaCity #travel

Calle 50

You can find out about the history of Panama City with a trip to Calle 50. Discover the area's shops, or seek out its local tours.

Calle 50

Santa Ana Hotel Deals

Casco View Apartments

Casco View Apartments

3.5 out of 5
C. 16 Oeste, Panama City, Provincia de Panamá
The price is ₩102,886 per night from Oct 22 to Oct 23
₩102,886
₩113,175 total
Oct 22 - Oct 23
includes taxes & fees
Stay at this 3.5-star condo in Panama City. Enjoy free WiFi, a 24-hour front desk, and a garden. Popular attractions Albrook Shopping Mall and Cinta Costera ...
9.2/10 Wonderful! (48 reviews)
"Great stay, would recommend."

Reviewed on Sep 4, 2025

Casco View Apartments
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
The price is ₩162,513 per night from Nov 4 to Nov 5
₩162,513
₩178,764 total
Nov 4 - Nov 5
includes taxes & fees
Stay at this 5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and 3 restaurants. Our guests praise the breakfast and the pool in our reviews. ...
9/10 Wonderful! (4,425 reviews)
"Great hotel for the price. Nice pool and the included breakfast was a plus. It was clean and staff was nice except for the service desk who appeared to be annoyed with me asking for wash cloths everyday since they failed at leaving any or not enough for me and my daughter. Other than that I had no ..."

Reviewed on Oct 20, 2025

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz, Corregimineto De Tocumen Hacia El, Tocumen, Panama
The price is ₩171,832 per night from Nov 1 to Nov 2
₩171,832
₩189,015 total
Nov 1 - Nov 2
includes taxes & fees
Stay at this 4-star family-friendly hotel in Tocumen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the breakfast and ...
8.4/10 Very Good! (2,255 reviews)
"Ideal ubicación para quien debe pasar una noche cerca del aeropuerto"

Reviewed on Oct 19, 2025

Crowne Plaza Panama Airport by IHG
Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive

4 out of 5
KM 7, Road to Veracruz, Veracruz, Panama
The price is ₩411,829 per night from Nov 18 to Nov 19
₩411,829
₩411,829 total
Nov 18 - Nov 19
includes taxes & fees
Stay at this 4-star beach property in Veracruz. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the pool and the helpful staff in our reviews. ...
7.4/10 Good! (1,011 reviews)
"Breakfast had good variety and fresh food daily - The ocean view was good.. staff was very friendly and helpful.. Aracely was fantastic an incredible housekeeper - She keep our room clean with fresh towels sheets everyday.. Our room was cleaned to perfection daily ..."

Reviewed on Oct 19, 2025

Dreams Playa Bonita Panama - All Inclusive
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa, Panama City
The price is ₩183,220 per night from Nov 9 to Nov 10
₩183,220
₩201,542 total
Nov 9 - Nov 10
includes taxes & fees
Stay at this 4.5-star luxury hotel in Panama City. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in ...
8.4/10 Very Good! (1,138 reviews)
"Relaxing"

Reviewed on Oct 16, 2025

Megapolis Hotel Panamá
Marriott Panama Hotel

Marriott Panama Hotel

4 out of 5
Roosevelt Ave., Allbrook Mall, Panama City, Panama
The price is ₩190,648 per night from Nov 7 to Nov 8
₩190,648
₩209,720 total
Nov 7 - Nov 8
includes taxes & fees
Stay at this 4-star business-friendly hotel in Panama City. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,003 reviews)
"Clean rooms, real good shopping, safe, friendly staff, can speak English also"

Reviewed on Oct 19, 2025

Marriott Panama Hotel
See all 1,529 properties in Santa Ana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santa Ana

My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

Casco Viejo

4.5/5(178 area reviews)

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Casco Viejo
My favourite store in Casco Viejo by far! It sells #colorful Kuna handmade products and the owner of the gallery is a very kind lady, who even allowed me to visit her place outside working hours. #LikeALocal

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

San Felipe
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El Chorrillo

While there might not be top attractions in El Chorrillo, you can explore the larger area and discover places like Albrook Shopping Mall and Ancon Hill.

El Chorrillo
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Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Calidonia
The buses of Panama.

Balboa

The restaurants and shopping are a few reasons travelers visit Balboa. Though there aren't many top sights in the neighborhood, you can visit Albrook Shopping Mall and Bridge of the Americas, a few notable attractions nearby.

Balboa
Cinta Costera a wonderful pedestrian walkway with a separate lane for bicyclists and skateboarders #OrbitzTravel

Marbella

5/5(2 area reviews)

You'll enjoy the restaurants and parks in Marbella. You might want to make time for a stop at Avenida Balboa or Cinta Costera.

Marbella

Santa Ana