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Our top choices for Santa Ana hotels

1. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana
9.0 out of 10, Wonderful, (107 reviews)
"Amazing location and comfort"
United States
Ruben
The price is ₩105,954
₩156,759 total
includes taxes & fees
Oct 9 - Oct 10
Casco View Life Residences

2. Hotel Caracas - Casco Viejo

Hotel Caracas - Casco Viejo
3.0 star property
Santa Ana
8.0 out of 10, Very good, (19 reviews)
"great staff"
United States
Keith
The price is ₩51,630
₩56,790 total
includes taxes & fees
Oct 7 - Oct 8
Hotel Caracas - Casco Viejo

3. Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (197 reviews)
"Good location. Walking distance to shops and public transport."
Canada
Danilo
The price is ₩39,205
₩123,552 total
includes taxes & fees
Oct 7 - Oct 8
Hotel República

4. Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (75 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ₩39,358
₩43,294 total
includes taxes & fees
Oct 7 - Oct 8
Hostal La Cigarra

5. La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.6 out of 10, Good, (19 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ₩93,503
₩139,745 total
includes taxes & fees
Oct 7 - Oct 8
La Manzana Barrio Vivo by Wynwood

6. ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (13 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ₩49,349
₩54,284 total
includes taxes & fees
Nov 3 - Nov 4
ART CASCO The Hotel

7. Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ₩36,189
₩39,808 total
includes taxes & fees
Oct 7 - Oct 8
Hotel Riazor

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

Room-sofa Bed Stay Rooftop Pool & Gym, A
2.0 star property
Santa Ana
2.0 out of 10, (1 review)
"You pay for a space in the apartment, it’s not the whole apartment be careful. The owner or whoever manages doesn’t give care about you as costumers they just want the money"
United States
Cristian Camilo Betancur
The price is ₩162,335
₩178,568 total
includes taxes & fees
Oct 19 - Oct 20
Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (6,025 reviews)
"Clean rooms, amazing staff and good breakfast"
United States
Avanel
The price is ₩177,009
₩194,710 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Riu Plaza Panama

10. The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,274 reviews)
"great location, great hotel"
United States
Sandra
The price is ₩118,991
₩130,890 total
includes taxes & fees
Oct 21 - Oct 22
The Executive Hotel

11. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 1.1 km from Santa Ana
9.8 out of 10, Exceptional, (755 reviews)
"Amazing service and beautiful hotel"
United States
Jose
The price is ₩470,459
₩517,505 total
includes taxes & fees
Nov 4 - Nov 5
Sofitel Legend Casco Viejo, Panama City

12. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,235 reviews)
"I love the breakfast with it's increible view of the bay"
United States
Milton
The price is ₩145,230
₩145,230 total
includes taxes & fees
Oct 19 - Oct 20
Plaza Paitilla Inn Hotel

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
Punta Paitilla, 3.5 km from Santa Ana
8.6 out of 10, Excellent, (1,765 reviews)
"Hotel was amazing"
United States
Sheena
The price is ₩202,364
₩222,600 total
includes taxes & fees
Oct 31 - Nov 1
Megapolis Hotel Panamá

14. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (458 reviews)
"The hotel was a great surprise. Great friendly knowledgeable staff. Super modern room with great decor. Massive comfortable bed."
United States
Eric
The price is ₩205,166
₩225,683 total
includes taxes & fees
Oct 8 - Oct 9
Hotel San Felipe

15. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.9 km from Santa Ana
9.0 out of 10, Wonderful, (1,012 reviews)
"Great location and nice hotel."
United States
Olga
The price is ₩267,383
₩294,121 total
includes taxes & fees
Oct 11 - Oct 12
Central Hotel Panama Casco Viejo

16. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.7 km from Santa Ana
9.4 out of 10, Exceptional, (818 reviews)
"Beautiful hotel"
United States
Ashleigh-Ann
The price is ₩240,256
₩264,282 total
includes taxes & fees
Oct 12 - Oct 13
American Trade Hotel

17. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 5.1 km from Santa Ana
9.6 out of 10, Exceptional, (1,372 reviews)
"excellent breakfast great location"
United States
Maria
The price is ₩140,254
₩154,286 total
includes taxes & fees
Nov 1 - Nov 2
Ramada Plaza by Wyndham Panama Punta Pacifica

18. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 3.9 km from Santa Ana
9.0 out of 10, Wonderful, (2,087 reviews)
"Very large suites, comfortable beds, great A/C"
United States
Willis
The price is ₩79,254
₩87,175 total
includes taxes & fees
Oct 7 - Oct 8
Principe Hotel and Suites

19. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 3.5 km from Santa Ana
9.0 out of 10, Wonderful, (1,179 reviews)
"Breakfast was excellent"
United States
kevin
The price is ₩119,625
₩205,313 total
includes taxes & fees
Oct 9 - Oct 10
Waymore Hotel Spa & Casino

20. Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
4.0 star property
Bella Vista, 3.3 km from Santa Ana
7.8 out of 10, Good, (1,002 reviews)
"Great hotel"
United States
Althea
The price is ₩137,295
₩151,031 total
includes taxes & fees
Oct 19 - Oct 20
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.
Casco View Life Residences
4.0 star property
9.0
Wonderful
107 reviews
View
A hotel corridor with a wooden door, a number plaque, and a railing.
Hotel Caracas - Casco Viejo
3.0 star property
8.0
Very good
19 reviews
View
A restaurant with a long counter, chairs, and tables. There are plants and lights decorating the space.
Hostal La Cigarra
2.0 star property
7.6
Good
75 reviews
View
A modern hotel room with a large bed, a sofa, a TV, and a view of the city.
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.6
Good
19 reviews
View
A hotel room with a large bed, a window with curtains, a city view, and a lamp.
Hotel República
2.0 star property
6.8
197 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

If you're spending some time in San Felipe, Independence Square and Interoceanic Canal Museum are top sights worth seeing.

Top Santa Ana Hotel Reviews

Find out more about Santa Ana

Top reasons to visit Santa Ana

  • Family-Friendly Atmosphere: Santa Ana offers a welcoming environment suitable for families, making it an ideal vacation destination.
  • Cultural Exploration: Discover local attractions like the Santa Ana Church and the San Miguel area, rich in history and culture.
  • Vibrant Neighborhood: Wander through charming streets filled with friendly locals, showcasing the unique Panamanian vibe.
  • Diverse Activities: Enjoy shopping at local malls, exploring parks, and taking walking tours to experience the area's charm.
  • Variety of Accommodations: Choose from pet-friendly hotels to city-themed apartments, catering to every traveler's needs.

Find great hotels near Santa Ana

Discover a variety of accommodation options in Santa Ana, Panama, perfect for every traveler. From pet-friendly hotels to city-themed apartments, you'll find the ideal setting for your business trip or vacation. Explore popular choices like Hotel El Panama and other Panama City hotels, as well as vacation rentals that cater to your needs. Enjoy a memorable stay in the vibrant heart of Panamá Province.

  • Central Hotel Panama Casco Viejo: A charming 4-star hotel located a short distance from Santa Ana, Central Hotel Panama Casco Viejo offers a romantic and city-themed experience perfect for couples. With an impressive guest rating of 9.2 out of 10, the hotel features enticing romance packages, allowing guests to indulge in special amenities like Champagne Service and 24-hour Room Service. The full-service spa and pool area provide a serene escape, offering Body Treatments, Manicures and Pedicures, and Facial Treatments for relaxation. Set in the heart of the city, this hotel combines historical charm with modern comforts, making it an ideal choice for a romantic getaway.
  • American Trade Hotel: This 4.5-star property, located just 644m from Santa Ana, boasts a guest rating of 9.4 out of 10 and is perfect for families and adventure-seekers. The American Trade Hotel offers a variety of outdoor activities, including nearby hiking, biking, and Segway rentals, ensuring a thrilling stay. Families can benefit from child-friendly amenities such as cribs and breakfast options for children. Guests can enjoy stunning garden views from the on-site restaurant and unwind by the outdoor pool, complete with sun loungers and massage services, making it a great choice for both adventure and relaxation.
  • Sofitel Legend Casco Viejo, Panama City: For travelers seeking a luxurious experience, the 5-star Sofitel Legend Casco Viejo is located 1km from Santa Ana and boasts an impressive guest rating of 9.8 out of 10. This opulent hotel offers high-end amenities, including multiple Treatment Rooms for massages and a beautiful outdoor pool. Ideal for business travelers and those looking for a spa-themed vacation, the hotel creates an atmosphere of sophistication and elegance, ensuring guests enjoy a lavish retreat in the vibrant city of Panama.

Where to stay near Santa Ana

Santa Ana, located in the vibrant Panamá Province, offers a delightful blend of family-friendly activities and a lively atmosphere. Explore the charming streets where friendly locals share the rich Panamanian vibe, and enjoy the nearby attractions that cater to both relaxation and business travelers. Immerse yourself in the best of Panama, from bustling markets to serene parks, making Santa Ana an ideal base for your unforgettable vacation experience.

  • Panama City: As the vibrant capital of Panama, Panama City boasts a dynamic urban landscape filled with skyscrapers and historic sites. Situated in the heart of the country, it serves as a hub for travelers seeking a mix of business and leisure. Visitors can enjoy a variety of shopping centers and malls, and explore local landmarks like parks and beaches. The city's diverse offerings make it an ideal destination year-round, particularly peaking in January, July, and September. It's a perfect spot for family outings or business ventures, providing ample opportunities for both relaxation and exploration.
  • Casco Viejo: Just 644m from Santa Ana, Casco Viejo is a historic neighborhood full of charm and character. Known for its stunning colonial architecture, this area is a UNESCO World Heritage site that attracts travelers seeking a cultural experience. The neighborhood's vibrant streets are lined with shops, restaurants, and beautiful parks, making it an ideal spot for leisurely strolls. Peak visitor numbers occur in January and during the spring months, ensuring a lively atmosphere. Whether you're exploring the local markets or enjoying seaside views, Casco Viejo offers a rich tapestry of experiences.
  • San Felipe: Also situated 644m from Santa Ana, San Felipe is another captivating neighborhood that embodies the essence of Panama's history and culture. Known for its picturesque streets and welcoming atmosphere, this area is popular among families and business travelers alike. With easy access to shopping areas, resorts, and local parks, visitors can enjoy a variety of activities. The neighborhood sees increased traffic in February, March, and December, making it a bustling hub of activity. San Felipe is perfect for those looking to immerse themselves in the local culture while enjoying convenient access to modern amenities.

Things to do near Santa Ana

Shopping

In Santa Ana, visit the bustling Albrook Mall, one of the largest shopping centers in Central America, featuring a wide range of stores, restaurants, and entertainment options. For a more local experience, check out the Santa Ana Market, where you can find unique crafts and souvenirs to take home.

Recreation

In Santa Ana, the Bliss Wellness Retreat offers rejuvenating yoga sessions and holistic therapies amidst tranquil surroundings. Nearby, the Urban Spa delivers a range of pampering treatments, including massages and facials, ensuring a relaxing experience after your adventures in Panama City.

Adventure

Gatun Eco Adventures offers an exhilarating zipline and ropes course experience, located 48km from Santa Ana. Feel the rush as you soar through the treetops and navigate challenging obstacles, surrounded by the stunning natural beauty of Panama's lush landscapes.

Nightlife

Experience the vibrant nightlife in Santa Ana. Visit Casa de la Cerveza for a variety of local brews, or enjoy live music at La Tana for a cozy atmosphere. For dancing, check out La Esquina, where you can groove to local DJs and enjoy themed nights.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santa Ana

Santa Ana in Panama City is a fantastic destination for families, business travelers, and city enthusiasts alike. Visitors can explore captivating sites such as the Santa Ana Church and the San Miguel area, while enjoying the local hills and history museums. Whether you're seeking cultural experiences or scenic outdoor adventures, Santa Ana offers a variety of attractions that cater to diverse interests, ensuring a memorable vacation for everyone.

  • Metropolitan Cathedral of Panama: Located 805m from Santa Ana, this stunning cathedral showcases beautiful architecture and rich cultural history. Visitors can admire its intricate facades and explore the serene interior, making it a significant landmark in Panama City.
  • Interoceanic Canal Museum: Just 805m away, this museum offers a fascinating insight into the history and impact of the Panama Canal. Through engaging exhibits, visitors can learn about the engineering marvel and its role in global trade while appreciating the local culture.
  • Independence Square: This lively square, located 805m from Santa Ana, is a hub of city life and culture. Surrounded by historical buildings, it’s an ideal spot to relax, take in the scenery, and observe local events.

Best time to go to Santa Ana

The best time to visit Santa Ana is dependent on what kind of holiday you are seeking. April is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. November is its coolest month on average. At this time, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January78.8°F (26.0°C)No RainMostly SunnyAverageSlightly High
February79.2°F (26.2°C)No RainMostly SunnySlightly HighAverage
March79.7°F (26.5°C)No RainMostly SunnySlightly HighSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageSlightly High
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudySlightly LowAverage
July79.3°F (26.3°C)Frequent RainMostly CloudyAverageAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly LowSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudyAverageSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly HighAverage

The nearest major airports for your trip to Santa Ana

Flying into Santa Ana, Panama is convenient, with three major airports nearby. Panama City (PAC-Marcos A. Gelabert Intl.) is situated 3km away, with excellent hotels like Hilton Panama and W Panama, both offering various airport shuttle services. Balboa (BLB-Panama Pacifico Intl.) is 6km from Santa Ana, featuring luxury options like The Westin Playa Bonita Panama. Lastly, Panama City (PTY-Tocumen Intl.) is 21km away, with hotels such as The Santa Maria, A Luxury Collection Hotel, providing accessible transportation to the airport. Each airport offers a range of transportation services to ensure a smooth arrival to your destination.

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Hotel Caracas - Casco Viejo is one of the top choices for your stay in Santa Ana. This hotel is a short 7-minute walk from Avenida Balboa, and it offers a restaurant and a bar. Another good choice for your stay in the area is Casco View Life Residences.
How many hotels can I expect to find in Santa Ana?
Expedia has 135 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.