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Our top choices for Santa Ana hotels

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (71 reviews)
"Excellent staff, close to metro and embassies. A good location, good room for a great price. I would stay again. "
United Kingdom
Mark
The price is ₩41,818
₩46,000 total
includes taxes & fees
Jun 3 - Jun 4
Hostal La Cigarra

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (97 reviews)
"Always an amazing stay"
United States
chris
The price is ₩134,551
₩193,401 total
includes taxes & fees
Jun 10 - Jun 11
Casco View Apartments

Hotel Riazor

Hotel Riazor
3.0 star property
Santa Ana
3.8 out of 10, (11 reviews)
"Rough neighborhood "
Canada
Del
The price is ₩40,621
₩44,683 total
includes taxes & fees
Jun 3 - Jun 4
Hotel Riazor

Hotel República

Hotel República
2.0 star property
Santa Ana
6.8 out of 10, (194 reviews)
"Very good ."
United States
Denice
The price is ₩44,260
₩139,484 total
includes taxes & fees
Jun 3 - Jun 4
Hotel República

La Manzana Barrio Vivo by Wynwood

La Manzana Barrio Vivo by Wynwood
3.0 star property
Santa Ana
7.4 out of 10, Good, (17 reviews)
"Very clean and safe property"
United States
Javier Alberto Lindauer
The price is ₩81,106
₩130,829 total
includes taxes & fees
Jun 3 - Jun 4
La Manzana Barrio Vivo by Wynwood

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
The price is ₩55,712
₩61,283 total
includes taxes & fees
Jun 3 - Jun 4
ART CASCO The Hotel

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,571 reviews)
"Great place to stay, restaurant is great also"
United States
Janet
The price is ₩198,225
₩228,034 total
includes taxes & fees
Jun 9 - Jun 10
Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very Good, (1,826 reviews)
"This hotel is very clean and the Staff are very friendly."
United States
Doreen
The price is ₩177,679
₩195,447 total
includes taxes & fees
Jun 17 - Jun 18
Riande Aeropuerto Hotel & Casino

ORHO Hotel Boutique 15 Minutes from PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (133 reviews)
"Lovely property, staff was always smiling and it's close to restaurants."
United States
Luis
The price is ₩154,761
₩200,880 total
includes taxes & fees
Jun 4 - Jun 5
ORHO Hotel Boutique 15 Minutes from PTY Airport

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,003 reviews)
"Always a pleasure to stay here"
United States
Rory
The price is ₩171,775
₩188,953 total
includes taxes & fees
Jun 22 - Jun 23
Courtyard by Marriott Panama Metromall

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.3 km from Santa Ana
8.6 out of 10, Excellent, (1,007 reviews)
"Excellent location, good parking."
United States
Mark
The price is ₩129,376
₩142,314 total
includes taxes & fees
Jun 29 - Jun 30
Radisson Hotel Panama Canal

Arcadia Condo Suites

Arcadia Condo Suites
4.0 star property
Costa del Este, 10.2 km from Santa Ana
9.2 out of 10, Wonderful, (297 reviews)
"Everything was amazing"
United States
James
The price is ₩141,420
₩165,492 total
includes taxes & fees
Jun 21 - Jun 22
Arcadia Condo Suites

Villa Caprichosa

Villa Caprichosa
2.5 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (71 reviews)
"Really good food, nice staff it was the best service! "
United States
junier
The price is ₩240,715
₩264,787 total
includes taxes & fees
Jun 16 - Jun 17
Villa Caprichosa

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very Good, (434 reviews)
"Very nice small hotel, comfortable excellent location on Amador Causeway. Close to Albrook Mall, Casco, Viejo…"
United States
David
The price is ₩112,565
₩123,822 total
includes taxes & fees
Jun 16 - Jun 17
The Beach House

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 3.5 km from Santa Ana
8.8 out of 10, Excellent, (951 reviews)
"Breakfast was great, rooms very clean"
United States
juanita
The price is ₩88,011
₩171,283 total
includes taxes & fees
Jun 9 - Jun 10
Waymore Hotel Spa & Casino

The Executive Hotel

The Executive Hotel
3.5 star property
Campo Alegre, 3.2 km from Santa Ana
9.2 out of 10, Wonderful, (1,127 reviews)
"Great service and friendly staff"
United States
Lillian
The price is ₩133,446
₩146,791 total
includes taxes & fees
Jun 17 - Jun 18
The Executive Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (700 reviews)
"Stunning ! Beautiful Hotel ! Excelent Service Delicious Food Luxury modern room Can’t wait to go back ! Love it so much !"
United States
Marina
The price is ₩362,026
₩398,236 total
includes taxes & fees
Jun 12 - Jun 13
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco, 5.7 km from Santa Ana
8.6 out of 10, Excellent, (1,001 reviews)
"Solid property with excellent staff."
United States
Craig
The price is ₩212,449
₩233,693 total
includes taxes & fees
Jun 9 - Jun 10
Sheraton Grand Panama

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
Amador, 4.8 km from Santa Ana
8.0 out of 10, Very Good, (255 reviews)
"The breakfast was good and lots of parking in a safe place "
United States
Tessa
The price is ₩117,452
₩129,194 total
includes taxes & fees
Jun 8 - Jun 9
MARINN Tropical Vibes Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,166 reviews)
"One of my favorite hotels in Panama City, always a great experience and lots of things to do close by, the best breakfast buffet in the area."
United States
Danny
The price is ₩156,263
₩171,889 total
includes taxes & fees
Jun 19 - Jun 20
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, sun loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
97 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
71 reviews
View
Apartment (20) | Iron/ironing board, free WiFi, bed sheets
La Manzana Barrio Vivo by Wynwood
3.0 star property
7.4
Good
17 reviews
View
Beach shuttle
Hotel República
2.0 star property
6.8
194 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Calidonia

You might enjoy the shopping while in Calidonia. Via Espana is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighborhood that travelers like for its seafood restaurants, shopping, and parks. Are you looking for Santa Ana travel tips? Be sure to check out Avenida Balboa and El Machetazo Santa Ana while you're in the neighborhood.
Where is the best hotel for a stay in Santa Ana?
Based on our traveler data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.
How many hotels can I expect to find in Santa Ana?
Expedia has 117 hotels and other accommodations in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! Most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in Santa Ana.
Where can I learn more about changing or cancelling my trip to Santa Ana?
To find more details about picking new dates or cancelling your trip to Santa Ana, head over to our customer service page.
What is there to do in this Panama City neighborhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.