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Compare 1,598 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Rodeway Inn & Suites
Enjoy a well-equipped kitchen with a coffee maker, microwave, and refrigerator.

Rodeway Inn & Suites

2.0 star property
7.6 out of 10, Good, (161)
"Great place to stay "
The price is ₩99,740
₩111,210 total
includes taxes & fees
Aug 21 - Aug 22
Rodeway Inn & Suites
Hampton Inn Anderson/ Alliance Business Park
Experience the Hampton Inn's modern architecture and landscaped surroundings.

Hampton Inn Anderson/ Alliance Business Park

2.5 star property
9.2 out of 10, Wonderful, (768)
"Friendly staff, clean facility, decent amount of options for breakfast, kids loved the pool "
The price is ₩158,516
₩175,951 total
includes taxes & fees
Aug 2 - Aug 3
Hampton Inn Anderson/ Alliance Business Park
Hampton Inn Hartwell
Welcome to Hampton Inn, featuring a modern architectural design with a prominent entrance and ample parking.

Hampton Inn Hartwell

2.5 star property
9.2 out of 10, Wonderful, (309)
"Great place to stay"
The price is ₩163,141
₩194,515 total
includes taxes & fees
Aug 16 - Aug 17
Hampton Inn Hartwell
Fairfield Inn & Suites Seneca Clemson Univ Area
Enjoy meals and gatherings with friends and family in this lakeside patio area, surrounded by trees and a scenic view.

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (177)
"Liked the view of the lake and the large breakfast area. Breakfast was excellent."
The price is ₩178,108
₩195,920 total
includes taxes & fees
Jul 24 - Jul 25
Fairfield Inn & Suites Seneca Clemson Univ Area
Postcard Cabins Lake Hartwell
Relax in a secluded cabin surrounded by the forest, with a cozy deck and fire pit.

Postcard Cabins Lake Hartwell

2.0 star property
10.0 out of 10, Exceptional, (12)
"Clean and cute Wonderful getaway "
The price is ₩122,881
₩188,325 total
includes taxes & fees
Jul 24 - Jul 25
Postcard Cabins Lake Hartwell
Hampton Inn & Suites Seneca-Clemson Area
Experience the warm welcome at this inviting hotel, featuring a prominent entrance and comfortable accommodations.

Hampton Inn & Suites Seneca-Clemson Area

2.5 star property
9.4 out of 10, Exceptional, (611)
"convenient to our needs"
The price is ₩167,421
₩184,163 total
includes taxes & fees
Jul 27 - Jul 28
Hampton Inn & Suites Seneca-Clemson Area
Quality Inn Seneca Clemson Area US-123
Enjoy a meal at our restaurant with a counter, display case, and comfortable seating areas.

Quality Inn Seneca Clemson Area US-123

2.5 star property
8.0 out of 10, Very Good, (612)
"Very nice property. I would recommend to stay here"
The price is ₩110,592
₩135,325 total
includes taxes & fees
Jul 29 - Jul 30
Quality Inn Seneca Clemson Area US-123
Tru by Hilton Seneca Clemson
Enjoy a convenient stay with a central counter area offering a variety of essentials.

Tru by Hilton Seneca Clemson

2.5 star property
9.2 out of 10, Wonderful, (739)
"Excellent location and superior welcoming staff"
The price is ₩151,392
₩166,532 total
includes taxes & fees
Aug 3 - Aug 4
Tru by Hilton Seneca Clemson
Best Western Seneca-Clemson
Welcome to our reception area, featuring a reception desk and a geometric patterned wall.

Best Western Seneca-Clemson

2.5 star property
8.4 out of 10, Very Good, (597)
"The admission attendant was friendly"
The price is ₩127,920
₩140,713 total
includes taxes & fees
Jul 29 - Jul 30
Best Western Seneca-Clemson
Lakeside Lodge Clemson
Stunning residential building with a central courtyard featuring a swimming pool, lounge areas, and outdoor seating.

Lakeside Lodge Clemson

2.5 star property
9.0 out of 10, Wonderful, (954)
"Great overall stay."
The price is ₩136,687
₩169,658 total
includes taxes & fees
Jul 24 - Jul 25
Lakeside Lodge Clemson
Days Inn by Wyndham Seneca / Clemson Area
Welcome to our hotel lobby, featuring a reception desk, comfortable seating, and a warm atmosphere.

Days Inn by Wyndham Seneca / Clemson Area

2.0 star property
6.8 out of 10, (690)
"The property was near the area that I needed to be in. It has ample shops and restaurants in the area "
The price is ₩96,233
₩105,857 total
includes taxes & fees
Jul 28 - Jul 29
Days Inn by Wyndham Seneca / Clemson Area
Rodeway Inn
Two large beds with white linens and a wooden headboard, a desk with a flat-screen TV and lamp, and a large window with an outdoor view.

Rodeway Inn

2.0 star property
7.6 out of 10, Good, (280)
"Very friendly, loved my stay there"
The price is ₩93,196
₩103,448 total
includes taxes & fees
Jul 29 - Jul 30
Rodeway Inn
Hampton Inn & Suites Lavonia
Enjoy al fresco dining on the patio with tables and chairs, surrounded by a brick wall and windows.

Hampton Inn & Suites Lavonia

2.5 star property
9.0 out of 10, Wonderful, (347)
"great stay, Maddie was the best"
The price is ₩180,731
₩214,743 total
includes taxes & fees
Aug 1 - Aug 2
Hampton Inn & Suites Lavonia
Clemson University's James F. Martin Inn
Enjoy a serene golf experience with a tranquil lake view.

Clemson University's James F. Martin Inn

3.0 star property
9.6 out of 10, Exceptional, (904)
"Great stay!"
The price is ₩205,721
₩228,350 total
includes taxes & fees
Jul 24 - Jul 25
Clemson University's James F. Martin Inn
Holiday Inn Express Anderson by IHG
Hotel entrance with covered walkway and symmetrical facade.

Holiday Inn Express Anderson by IHG

2.5 star property
8.6 out of 10, Excellent, (372)
"It is good"
The price is ₩155,327
₩172,414 total
includes taxes & fees
Jul 27 - Jul 28
Holiday Inn Express Anderson by IHG
Baymont by Wyndham Easley/Greenville
Relax in this inviting living room with a sofa set, coffee table, and armchair, offering a view of the outdoors through large glass doors.

Baymont by Wyndham Easley/Greenville

2.5 star property
7.2 out of 10, Good, (677)
"Felt safe. Clean"
The price is ₩114,596
₩127,202 total
includes taxes & fees
Jul 30 - Jul 31
Baymont by Wyndham Easley/Greenville
Days Inn by Wyndham Anderson
Enjoy a delicious breakfast at the Daybreak Breakfast buffet, featuring a variety of cereals and pastries.

Days Inn by Wyndham Anderson

2.0 star property
7.4 out of 10, Good, (1008)
"Great stay "
The price is ₩80,977
₩89,884 total
includes taxes & fees
Jul 28 - Jul 29
Days Inn by Wyndham Anderson
Home2 Suites by Hilton Anderson Downtown
Relax in a comfortable outdoor space with seating options and overhead lighting.

Home2 Suites by Hilton Anderson Downtown

3.0 star property
9.2 out of 10, Wonderful, (182)
"Great hotel. "
The price is ₩197,575
₩219,307 total
includes taxes & fees
Aug 3 - Aug 4
Home2 Suites by Hilton Anderson Downtown
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Welcome to our reception area, featuring a modern design with a warm glow, wood, and metal elements.

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

2.5 star property
9.0 out of 10, Wonderful, (555)
"Nice rooms. Clean rooms, Comfortable beds,Friendly staff"
The price is ₩147,733
₩163,983 total
includes taxes & fees
Aug 1 - Aug 2
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
The Abernathy of Clemson
Enjoy meals in a spacious dining area with a large window offering views of the surrounding greenery.

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (531)
"Very nice staff, beautiful rooms"
The price is ₩247,279
₩274,479 total
includes taxes & fees
Aug 3 - Aug 4
The Abernathy of Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas and neighborhoods for the activities you enjoy most.
Pine Ridge Point map

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Serenity Bay map

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Indian Oaks map

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Keowee Reservoir.

Downtown map

Downtown

2 out of top 10 points of interest in this area

While visiting Downtown, you might make a stop by sights like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation map

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Keowee Reservoir, some noteworthy sights in the nearby area.

Learn more about Seneca

Escape to Seneca! Enjoy its sports, lake views, and coffee.

See all hotels in Seneca
View from the dike in Clemson, SC. This trail is used by runners, bikers, and lots of dog walkers.
Photo by Cindy Keese
Open Photo by Cindy Keese

Best guest reviews of Seneca

8.0/10
Good

Enjoyed some of the local shops. Lots of antique / thrift stores. Thoroughly enjoyed Timber Ridge Axe Throwing and Yesterdaze.

Kelly

Top Seneca Hotel Reviews

Postcard Cabins Lake Hartwell

Postcard Cabins Lake Hartwell

10/10 Excellent
"This cabin was amazing! It had everything you could think of. Fully stocked kitchen, water, coffee with creamers, firewood outside in the box. They even had a corkscrew. They really thought of everything. Check in was super easy. I will definitely use Postcard cabins again. "
Keith 1-night trip
Posted 2 days ago
Postcard Cabins Lake Hartwell

Frequently asked questions

Where is the best place for a stay in Seneca?

Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel offers free breakfast and free parking. Traveler reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.

If I need to cancel my hotel reservation in Seneca, will I receive a refund?

Yes, the majority of hotel reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.

Where can I learn more about changing or cancelling my trip to Seneca?

To find more details about updating your trip to Seneca or cancelling it, click here.

What's the best budget-friendly accommodation in Seneca?

Based on reviews, Quality Inn Seneca US-123 is a popular 2.5-star hotel for our travelers looking for an economical choice, and features free breakfast and free WiFi. View all budget hotels in Seneca.

What's the best place to stay for a family vacation to Seneca?

Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Attractions in the area like Ultimate Action Sports are also fun for the whole family. Find more child-friendly accommodations in Seneca.

What's the best LGBTQ-friendly place to stay in Seneca?

Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free WiFi. Tru by Hilton Seneca Clemson is another good choice for your stay. See all available hotels listed as LGBTQ-friendly in Seneca.

What's the best pet-friendly accommodation in Seneca?

Lakeside Lodge Clemson is a top hotel for people traveling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices to stay with your pet include Tru by Hilton Seneca Clemson and Days Inn by Wyndham Seneca / Clemson Area. See more pet-friendly hotel accommodations in Seneca.

What are some hotels with pools in Seneca?

Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool, and complimentary wireless internet access. Fairfield Inn & Suites Seneca Clemson Univ Area and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels with an onsite pool. View all hotels with pools in Seneca.

What is the best accommodation for staying close to Greenville-Spartanburg International Airport (GSP)?

Wyndham Garden Greenville Airport is one of the top choices for your stay and is a popular 3-star hotel featuring free breakfast and a restaurant. It's located 3.8 mi (6.1 km) from Greenville-Spartanburg Intl. Airport. Other good options near the airport include Best Western Greenville Airport Inn and Extended Stay America - Greenville - Airport.

What is staying in Seneca like?

Visitors to Seneca are sure to enjoy the sporting events, lakeside setting, and university setting. Welcoming and scenic, this city also attracts tourists with its coffeehouses. In Seneca, there are 285 hotels and other accommodations to choose from. Find out more about Seneca.

What should I do while I'm visiting Seneca?

Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee, and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Check out what more to see and do in Expedia's Seneca guide.

What's the weather like in Seneca?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Seneca is 62 inches.