Find hotels in South Jefferson, Roanoke

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 25 - Dec 26
Tomorrow
Dec 26 - Dec 27
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Filter by

Guest rating
Guest rating
Star rating

Our top choices for South Jefferson hotels

Lobby
SpringHill Suites by Marriott Roanoke

SpringHill Suites by Marriott Roanoke

SpringHill Suites by Marriott Roanoke
3.0 star property
South Jefferson
9.0 out of 10, Wonderful, (1001)
"Clean room, good location. "
United States
Elizabeth
The price is ₩198,278
₩224,649 total
includes taxes & fees
Jan 2 - Jan 3, 2026
SpringHill Suites by Marriott Roanoke
Premium Single Room | In-room safe, desk, laptop workspace, iron/ironing board
Rocky mount motel

Rocky mount motel

Rocky mount motel
2.0 star property
24.6 km from South Jefferson
9.0 out of 10, Wonderful, (8)
"Check-in was great. Very nice and courteous and room was nice and the bed was very comfortable. I would definitely stay here again. "
United States
Richard
The price is ₩128,519
₩144,327 total
includes taxes & fees
Dec 26 - Dec 27
Rocky mount motel
Comfort Double Room Single Use | Desk, laptop workspace, iron/ironing board, free WiFi
Lakeinn

Lakeinn

Lakeinn
2.5 star property
25.5 km from South Jefferson
7.4 out of 10, Good, (139)
"Friendly owner, great stay for families!"
United States
Catherine
The price is ₩111,105
₩124,771 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Lakeinn
Free daily continental breakfast
Quality Inn Troutville - Roanoke North

Quality Inn Troutville - Roanoke North

Quality Inn Troutville - Roanoke North
2.5 star property
15.2 km from South Jefferson
8.2 out of 10, Very Good, (1000)
"Good over all travel lodge clean comgortable suprising breakfast hood rest to get on the road again"
United States
John
The price is ₩119,855
₩134,597 total
includes taxes & fees
Jan 16 - Jan 17, 2026
Quality Inn Troutville - Roanoke North
Exterior
Fairfield Inn & Suites by Marriott Roanoke Hollins/I-81

Fairfield Inn & Suites by Marriott Roanoke Hollins/I-81

Fairfield Inn & Suites by Marriott Roanoke Hollins/I-81
2.5 star property
Alpine Hills, 11.1 km from South Jefferson
9.0 out of 10, Wonderful, (429)
"The room was very clean and the staff was excellent."
United States
John
The price is ₩171,840
₩192,975 total
includes taxes & fees
Dec 26 - Dec 27
Fairfield Inn & Suites by Marriott Roanoke Hollins/I-81
Front of property
The West End Flats

The West End Flats

The West End Flats
4.5 star property
West End, 1.8 km from South Jefferson
9.4 out of 10, Exceptional, (80)
"Room was exactly as described. Great location - fit my needs as needed"
United States
John
The price is ₩137,183
₩155,428 total
includes taxes & fees
Dec 28 - Dec 29
The West End Flats
Terrace/patio
Hampton Inn Roanoke/Hollins - I-81

Hampton Inn Roanoke/Hollins - I-81

Hampton Inn Roanoke/Hollins - I-81
2.5 star property
Alpine Hills, 10.9 km from South Jefferson
8.4 out of 10, Very Good, (743)
"Everything was great, staff, room, location. "
United States
Tanya
The price is ₩131,436
₩147,603 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Roanoke/Hollins - I-81
In-room safe, desk, free cribs/infant beds, free WiFi
Super 8 by Wyndham Roanoke VA

Super 8 by Wyndham Roanoke VA

Super 8 by Wyndham Roanoke VA
2.0 star property
8.8 km from South Jefferson
5.2 out of 10, (1001)
"Had a wonderful stay! Thanks so much Super 8!"
United States
Justin
The price is ₩81,025
₩90,992 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Super 8 by Wyndham Roanoke VA
Indoor pool, outdoor pool
Holiday Inn Express Hotel & Suites Rocky Mount by IHG

Holiday Inn Express Hotel & Suites Rocky Mount by IHG

Holiday Inn Express Hotel & Suites Rocky Mount by IHG
2.5 star property
28 km from South Jefferson
8.6 out of 10, Excellent, (743)
"Clean room, convenient location and good breakfast. "
United States
Patricia
The price is ₩145,010
₩163,572 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Holiday Inn Express Hotel & Suites Rocky Mount by IHG
Exterior
Hampton Inn Daleville

Hampton Inn Daleville

Hampton Inn Daleville
2.5 star property
18 km from South Jefferson
9.6 out of 10, Exceptional, (48)
"Clean, quiet hotel!"
United States
Melanie
The price is ₩140,908
₩158,239 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hampton Inn Daleville
Desk, blackout drapes, iron/ironing board, free WiFi
Days Inn by Wyndham Roanoke/Hollins Near I-81

Days Inn by Wyndham Roanoke/Hollins Near I-81

Days Inn by Wyndham Roanoke/Hollins Near I-81
2.0 star property
Alpine Hills, 11.3 km from South Jefferson
7.4 out of 10, Good, (1001)
"Clean room, friendly staff, good breakfast options."
United States
Heather
The price is ₩104,331
₩117,163 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Days Inn by Wyndham Roanoke/Hollins Near I-81
Suite (Conspiracy Suite) | Premium bedding, iron/ironing board, free WiFi, wheelchair access
Early Inn at the Grove

Early Inn at the Grove

Early Inn at the Grove
4.0 star property
29.6 km from South Jefferson
9.6 out of 10, Exceptional, (143)
"It was a fantastic stay. The location for shows is perfect."
United States
Derik
The price is ₩244,041
₩275,290 total
includes taxes & fees
Dec 26 - Dec 27
Early Inn at the Grove
Reception
Comfort Inn & Suites Troutville-Roanoke North

Comfort Inn & Suites Troutville-Roanoke North

Comfort Inn & Suites Troutville-Roanoke North
2.5 star property
15.4 km from South Jefferson
9.2 out of 10, Wonderful, (1301)
"Nice staff … had extra pillows when asked "
United States
Bennie
The price is ₩119,450
₩134,142 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Inn & Suites Troutville-Roanoke North
Exterior
Quality Inn Tanglewood

Quality Inn Tanglewood

Quality Inn Tanglewood
2.5 star property
Franklin-Colonial, 3.7 km from South Jefferson
7.2 out of 10, Good, (411)
"I have had no issues at this place and I return on a regular basis as a travel nurse; I just need a bed and a shower. No complaints from me. "
United States
Ryan
The price is ₩76,722
₩86,926 total
includes taxes & fees
Jan 25 - Jan 26, 2026
Quality Inn Tanglewood
Hypo-allergenic bedding, in-room safe, desk, blackout drapes
Hyatt Place Roanoke Airport/Valley View Mall

Hyatt Place Roanoke Airport/Valley View Mall

Hyatt Place Roanoke Airport/Valley View Mall
3.0 star property
Roundhill, 6.1 km from South Jefferson
8.6 out of 10, Excellent, (1000)
"Absolutely very neat and very comfortable to stay overnight! Enjoyed to go shopping near our hotel! Also restaurant! "
United States
Wayne
The price is ₩145,847
₩165,246 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hyatt Place Roanoke Airport/Valley View Mall
Exterior detail
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 

Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 
4.0 star property
Gainsboro, 1.8 km from South Jefferson
9.4 out of 10, Exceptional, (1000)
"Nice updated room in the wellness area of the hotel. Heated bathroom floors a definite plus. Beautiful christmas decor"
United States
Allison
The price is ₩247,478
₩280,392 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton 
Free daily continental breakfast
Best Western Plus Inn at Valley View

Best Western Plus Inn at Valley View

Best Western Plus Inn at Valley View
2.5 star property
Roundhill, 6.1 km from South Jefferson
8.4 out of 10, Very Good, (1002)
"The front desk attendant Bobbi Jo went above and beyond the call of duty for me and I truly appreciate it. Will stay here again!"
United States
Jacob
The price is ₩117,226
₩132,816 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Inn at Valley View
Lobby
The Liberty Trust

The Liberty Trust

The Liberty Trust
4.0 star property
Downtown Roanoke, 1.5 km from South Jefferson
9.2 out of 10, Wonderful, (1300)
"Great space....great staff... "
United States
Tricia
The price is ₩211,744
₩239,903 total
includes taxes & fees
Jan 25 - Jan 26, 2026
The Liberty Trust
Free breakfast
Holiday Inn Express Troutville by IHG

Holiday Inn Express Troutville by IHG

Holiday Inn Express Troutville by IHG
2.5 star property
15.4 km from South Jefferson
9.4 out of 10, Exceptional, (797)
"Excellently "
United States
MacGregor
The price is ₩158,338
₩177,814 total
includes taxes & fees
Dec 26 - Dec 27
Holiday Inn Express Troutville by IHG
Lobby
Comfort Inn Airport

Comfort Inn Airport

Comfort Inn Airport
2.5 star property
Airport, 6.7 km from South Jefferson
8.6 out of 10, Excellent, (826)
"Great place to stay!!!!"
United States
Ronald
The price is ₩117,804
₩133,473 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Comfort Inn Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in South Jefferson

Find the best South Jefferson areas and neighborhoods for the activities you enjoy most.
Roanoke which includes interior views
Photo by Roanoke Valley Convention & Visitors Bureau
Open Photo by Roanoke Valley Convention & Visitors Bureau

Downtown Roanoke

While visiting Downtown Roanoke, you might make a stop by sights like Center in the Square and Virginia Museum of Transportation.

Old Southwest

Boasting a mix of architectural styles like Queen Anne and Colonial Revival, this historic district home to Roanoke's first public park, Highland Park, and the Beth Israel Synagogue, with commercial areas concentrated along Franklin Road.

Norwich

While there might not be top attractions in Norwich, you can explore the larger area and discover places like Jefferson Center and The River Rock.

Wasena

While Wasena isn't home to many top sights, Jefferson Center and The River Rock are some notable places to visit nearby.

Greater Raleigh Court

If you're looking for some top things to see and do in Greater Raleigh Court and surrounding area, you can visit Jefferson Center and Shaftman Performance Hall.

Top South Jefferson Hotel Reviews

Spark by Hilton Roanoke Civic Center

Spark by Hilton Roanoke Civic Center

10/10 Excellent
"Friendly staff, budget friendly and clean!"
Jay 1-night trip
Posted 2 days ago
Spark by Hilton Roanoke Civic Center

Frequently asked questions

What is South Jefferson like?
Guests are sure to enjoy their time checking out all that Roanoke's South Jefferson neighborhood has to offer.
What's a favorite place to stay in South Jefferson?
Based on Expedia customer reviews, SpringHill Suites by Marriott Roanoke is the highest ranked property in South Jefferson. This hotel offers free breakfast and a restaurant.
If I need to cancel my hotel reservation in South Jefferson, will I receive a refund?
Yes, the majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the top deals on offer in South Jefferson.
Where can I learn more about changing or cancelling my trip to South Jefferson?
For more details about updating your trip to South Jefferson or cancelling it, click here.
What is there to do around this Roanoke neighborhood?
A few places to visit in the area around South Jefferson include River's Edge Sports Complex, Roanoke City Public Library, and Mill Mountain Star. When you're sightseeing in Roanoke, Mill Mountain Zoo and Arts Council of the Blue Ridge are also worth a stop.