Southeastern Indiana Vacations
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Where to stay in Southeastern Indiana
Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
West Main Historic District
Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.
Madison Historic District
If you're spending some time in Madison Historic District, Historic District and Lanier Mansion are top sights worth seeing.
Portland
While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.
Downtown French Lick
While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.
California
If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.
Find the Best Southeastern Indiana Vacation Packages
Southeastern Indiana Hotel Deals
Radisson Hotel Louisville North
505 Marriott Drive Clarksville IN
Fully refundable
₩95,293
₩107,682 total
Oct 24 - Oct 25
includes taxes & fees
7.2/10 Good! (3,416 reviews)
"Great stay! Location was very convenient."
Reviewed on Sep 23, 2026
Derby Hotel & Suites
505 K Marriot Dr Clarksville IN
Fully refundableReserve now, pay when you stay
₩64,038
₩72,362 total
Sep 28 - Sep 29
includes taxes & fees
7/10 Good! (208 reviews)
"The room was clean, it served its purpose, however, the area was a bit sketchy, a lot of drug users in the area."
Reviewed on Sep 23, 2026
Hampton Inn New Albany Louisville West
411 W Spring Street New Albany IN
Fully refundableReserve now, pay when you stay
₩132,250
₩149,442 total
Oct 11 - Oct 12
includes taxes & fees
8.8/10 Excellent! (906 reviews)
"Just in a great location easy access to the highway"
Reviewed on Sep 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southeastern Indiana attractions
KFC Yum Center
8.8/10 (1,621 reviews)
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.
Whiskey Row
9.2/10 (11 reviews)
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
Louisville Slugger Museum
9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
Photo by Nura Mirzaliyeva
Fourth Street Live!
8.4/10 (2,560 reviews)
You can do some window-shopping at Fourth Street Live! during your stay in Louisville. Experience the area's entertainment choices and lively festivals.
Clifty Falls State Park
9.2/10 (183 reviews)
You can take time to visit Clifty Falls State Park during your travels to Madison. Stroll along the riverfront or discover the area's waterfalls.
Photo by Mark Wilcoxson
Louisville Waterfront Park
8.8/10 (668 reviews)
After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its acclaimed art scene.
Kentucky International Convention Center
8.4/10 (763 reviews)
Learn about the events happening at Kentucky International Convention Center during your trip to Louisville. Amble around the area's riverfront or attend a sporting event.
Louisville Palace
8.2/10 (488 reviews)
You can get tickets for a performance at Louisville Palace on your trip to Louisville. Experience the area's acclaimed theater scene or attend a sporting event.
Frequently asked questions
How much does a Southeastern Indiana vacation package cost?
Our Southeastern Indiana vacation packages, which start from just , are an ideal way to save loads of cash. Pick and choose your preferred flights, hotels and rental cars to create a custom-built escape.
How do I get a cheap travel package to Southeastern Indiana?
If you love landing a bargain, bundle your bookings into a Southeastern Indiana vacation package. Whether you need flights, hotels, activities or rental cars, you can browse and book everything in one place. You'll have loads of choice at your fingertips too. Expedia has over 550 partner airlines and 1,000,000 hotel options throughout the world to choose from. Fly with who you want, stay wherever you like and save your hard-earned money — now that's the ideal escape!
Where should I stay in Southeastern Indiana?
You'll adore Louisville. Well-known attractions, such as Churchill Downs and Muhammad Ali Center, will keep you entertained in this happening city.
What are the top hotels in Southeastern Indiana?
Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville know how to make their guests feel at home in Louisville. If you also plan to stay in Jeffersonville - Clarksville, have a look at Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis. Both are top picks with travelers.
How far in advance should I book my Southeastern Indiana vacation?
It can be difficult to know when is the perfect time to book your Southeastern Indiana vacation. But usually the earlier you book, the more affordable the prices. In some cases, you can book your flights and hotels up to 12 months prior to your departure date. If you're thinking of a last-minute getaway, no need to fret! There are fabulous deals posted on Expedia every single day.
What does an Expedia Southeastern Indiana travel package include?
Packages include rental cars, flights and hotels, but you can mix and match them to create your perfect Southeastern Indiana vacation. You can also add on fun things like experiences and activities once you've made your booking. You're in the driver's seat! When you bundle your bookings with Expedia, you'll get access to deals you won't find anywhere else.
What should I know before booking a Southeastern Indiana travel package?
Whether it's adventure or relaxation you're craving, a Southeastern Indiana vacation package lets you organize your escape your way. Plus, you'll get access to great discounts just for combining your hotel with your rental car and flights. The more you bundle, the bigger the savings!
Can I choose my airline with a Southeastern Indiana Expedia vacation package?
Expedia has access to more than 550 partner airlines globally, so you definitely can. Just select your preferred carrier and craft your ideal Southeastern Indiana escape.
If I'm not able to travel, can I cancel my Southeastern Indiana vacation package?
Whether it's your hotel, flight or rental car, you can cancel or alter it. Booked your Southeastern Indiana vacation package in the last 24 hours? You may be able to make changes at no cost. For bookings made more than 24 hours ago, you may be charged a fee by your airline, hotel or car rental company. For further information, look up our Customer Service Portal. We'll help you each step of the way.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
