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Top Beach Southeast Jacksonville Hotels

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

13733 Beach Blvd Jacksonville FL

4 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...

8.8/10 Excellent! (1,000 reviews)

Very clean. Staff friendly and courteous.

Reviewed on Jan 13, 2026

Wyndham Garden Jacksonville

4660 Salisbury Road Jacksonville FL

10 min drive from Mayo Clinic Florida

Settle in and relax at this hotel and watch the sunset on the beach in Jacksonville, as you'll be not far from the beach. A beach bar, an outdoor pool, and a ...

7.8/10 Good! (1,786 reviews)

Travelers like: close to beach, beach bars, outdoor pool

Travelers say...

Very accommodating

Reviewed on Jan 10, 2026

Delta Hotels by Marriott™ Jacksonville Deerwood

4700 Salisbury Rd Jacksonville FL

10 min drive from Mayo Clinic Florida

Book a stay at this business-friendly hotel in Jacksonville. Enjoy free parking, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful ...

8.4/10 Very Good! (503 reviews)

Arrived in around noon for an early check in. After a long early drive. There was a fee of $50 but gave us discount for half price. Worth it since we were tired and wanted to rest. Hotel is near highway and restaurants. Clean, spacious room and bathroom.

Reviewed on Jan 12, 2026

See all 547 properties in Southeast Jacksonville

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.