Photo by Lancaster

Plan, book, travel with confidence
Better together
Save up to ₩1,660,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Luxury Central Mississippi Hotels

Microtel Inn & Suites by Wyndham Meridian

518 Bonita Lakes Dr Meridian MS

3 hours drive from Mississippi State University

Microtel Inn & Suites by Wyndham Meridian provides luxe lodging where you'll enjoy premium channels and more.

6.2/10 (999 reviews)

"En la aviation de arriba. Alguen de echo toda la noche caminando y el charro ilia muy mal 👎👎👎"

Reviewed on May 13, 2026

Red Roof Inn Meridian

2219 S Frontage Rd Meridian MS

3 hours drive from Mississippi State University

Treat yourself to some luxurious accommodations at Red Roof Inn Meridian, where you can enjoy amenities like premium channels, flat-screen TVs, and more.

6.6/10 (954 reviews)

"The room service is terrible we stayed there over 4 nights and they never even changed our sheets or anything and said that we had a do not disturb up at the door and also no towels for daily bathing nasty bathtub"

Reviewed on May 23, 2026

Comfort Inn & Suites Columbus North

129 Brickerton St Columbus MS

32 min drive from Mississippi State University

Discover luxurious lodging at Comfort Inn & Suites Columbus North, where you can enjoy amenities like plush bedding, premium channels, and more. Deluxe amenities ...

7.4/10 Good! (846 reviews)

"It was clean and plenty of parking"

Reviewed on May 21, 2026

See all 475 properties in Central Mississippi

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.