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Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

10 min drive from Iowa State Fairgrounds

Treat yourself to a luxury stay at Des Lux Hotel, where you can enjoy amenities like designer toiletries, flat-screen TVs, and more. Notable amenities include ...

9.8/10 Exceptional! (1,077 reviews)

"Breakfast was poor quality but overall experience it was a nice hotel."

Reviewed on Jun 28, 2026

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

19 min drive from Iowa State Fairgrounds

Indulge yourself with upscale accommodations at Sonesta Essential Des Moines, where you'll enjoy amenities like premium channels and more.

7.4/10 Good! (1,008 reviews)

"Hotel is full of long term tenants. Hallways smell like marijuana and other drugs being burnt. Police were called to remove drunk occupant at 2:30am which turned into a standoff. The room above us had a huge fight that woke us up at 2:20am. This hotel is not safe. We left at 2:45am and continued ..."

Reviewed on Jun 30, 2026

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

28 min drive from Iowa State Fairgrounds

Treat yourself to a luxury stay at La Quinta Inn & Suites by Wyndham Des Moines West Clive, where you can enjoy amenities like plush bedding, HDTVs, and ...

8.8/10 Excellent! (1,002 reviews)

"Average."

Reviewed on Jun 28, 2026

See all 1,618 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.