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Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

1 hour drive from Iowa State University

Treat yourself to a luxury stay at Des Lux Hotel, where you can enjoy amenities like designer toiletries, flat-screen TVs, and more. Notable amenities include ...

9.8/10 Exceptional! (1,043 reviews)

The whole experience was great. The only negative was the lady who was working in the breakfast area. She assumed I was taking too many breakfast items. Instead of asking me about, she took it upon herself to call me out from across the room. I was bringing items to my husband who wasn't able to ...

Reviewed on Mar 12, 2026

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

1 hour drive from Iowa State University

Indulge yourself with upscale accommodations at Sonesta Essential Des Moines, where you'll enjoy amenities like premium channels and more.

7.4/10 Good! (1,001 reviews)

The hot tub in the room was awesome

Reviewed on Mar 6, 2026

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

1 hour drive from Iowa State University

Treat yourself to a luxury stay at La Quinta Inn & Suites by Wyndham Des Moines West Clive, where you can enjoy amenities like plush bedding, HDTVs, and ...

8.8/10 Excellent! (1,001 reviews)

Perfect

Reviewed on Mar 12, 2026

See all 1,608 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.