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Top Luxury Central Iowa Hotels

Des Lux Hotel

800 Locust St Des Moines IA

1 hour drive from Iowa State University

Treat yourself to a luxury stay at Des Lux Hotel, where you can enjoy amenities like designer toiletries, flat-screen TVs, and more. Notable amenities include ...

9.6/10 Exceptional! (1,026 reviews)

This hotel is absolutely beautiful. The most aesthetically pleasing place I've ever stayed. Everything was perfectly clean and the staff was super friendly and helpful. Best hotel breakfast I've had since pre-covid. I would have expected to pay much more for how lovely this place is. Cannot recommend ...

Reviewed on Nov 25, 2025

Sonesta Essential Des Moines

4755 Merle Hay Road Des Moines IA

1 hour drive from Iowa State University

Indulge yourself with upscale accommodations at Sonesta Essential Des Moines, where you'll enjoy amenities like premium channels and more.

7.4/10 Good! (1,018 reviews)

Only thing I'd say needed to be done is I've noticed not every room has an ice bucket & don't understand the 3 pillow thing either.

Reviewed on Nov 30, 2025

La Quinta Inn & Suites by Wyndham Des Moines West Clive

1390 Nw 118th St Clive IA

1 hour drive from Iowa State University

Treat yourself to a luxury stay at La Quinta Inn & Suites by Wyndham Des Moines West Clive, where you can enjoy amenities like plush bedding, HDTVs, and ...

8.6/10 Excellent! (1,005 reviews)

Room was clean and updated, staff was friendly and the breakfast was good.

Reviewed on Nov 24, 2025

See all 1,576 properties in Central Iowa

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.