Southeast Minnesota Luxury Vacations

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Top Luxury Southeast Minnesota Hotels

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
Kahler Grand Hotel offers luxe lodging where you'll enjoy premium bedding and more. Deluxe amenities at this hotel include an indoor pool, a 24-hour fitness ...
8.2/10 Very Good! (1,523 reviews)
Great stay but complicated arrival by car
"Both staffing arrival and Mayo Clinic construction will continue to be a challenge for guests at the Kahler Grand for a few months. Hopefully more bell/valet staff can be added and arrival moved back to proper entrance. Until then arrival by car for registration can be chaotic/-once insid at the ..."

Reviewed on Aug 17, 2025

Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
Indulge yourself with upscale accommodations at Med City Inn & Suites - Mayo Clinic Area, where you'll enjoy amenities like premium channels and more. Notable ...
7.8/10 Good! (1,002 reviews)
Ok
"Fine"

Reviewed on Aug 12, 2025

Med City Inn & Suites - Mayo Clinic Area
AmericInn by Wyndham Northfield

AmericInn by Wyndham Northfield

2.5 out of 5
1320 Bollenbacher Dr, Northfield, MN
  • 2 hours drive from Mayo Clinic
AmericInn by Wyndham Northfield offers a luxury stay. Popular amenities include an indoor pool and a hot tub.
8.2/10 Very Good! (592 reviews)
"It was completely fine."

Reviewed on Aug 8, 2025

AmericInn by Wyndham Northfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.