Southeast Minnesota Luxury Vacations

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Top Luxury Southeast Minnesota Hotels

Kahler Grand Hotel

Kahler Grand Hotel

3 out of 5
20 2nd Ave Sw, Rochester, MN
  • 2 min walk from Mayo Clinic
Kahler Grand Hotel offers luxe lodging where you'll enjoy premium bedding and more. Deluxe amenities at this hotel include an indoor pool, a 24-hour fitness ...
8.2/10 Very Good! (1,525 reviews)
"Construction outside of the hotel makes it difficult to enter or get Uber at the front door."

Reviewed on Aug 20, 2025

Kahler Grand Hotel
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw, Rochester, MN
  • 26 min walk from Mayo Clinic
Indulge yourself with upscale accommodations at Med City Inn & Suites - Mayo Clinic Area, where you'll enjoy amenities like premium channels and more. Notable ...
7.8/10 Good! (1,000 reviews)
Ok
"Fine"

Reviewed on Aug 12, 2025

Med City Inn & Suites - Mayo Clinic Area
AmericInn by Wyndham Northfield

AmericInn by Wyndham Northfield

2.5 out of 5
1320 Bollenbacher Dr, Northfield, MN
  • 2 hours drive from Mayo Clinic
AmericInn by Wyndham Northfield offers a luxury stay. Popular amenities include an indoor pool and a hot tub.
8.2/10 Very Good! (592 reviews)
"It was completely fine."

Reviewed on Aug 8, 2025

AmericInn by Wyndham Northfield
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.