Key Largo Luxury Vacations

Book a Luxury Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to ₩234,741 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Top Luxury Key Largo Hotels

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection

4.5 out of 5
97450 Overseas Highway, Key Largo, FL
  • 14 min drive from John Pennekamp Coral Reef State Park
Playa Largo Resort & Spa, Autograph Collection is one of the Key Largo luxury 4.5-star beach properties where you can treat yourself to pillowtop beds, Netflix, ...
8.8/10 Excellent! (1,005 reviews)
"This place is a gem for families, quiet and calm, pool area and private beach area was amazing and service excelent"

Reviewed on Sep 14, 2025

Playa Largo Resort & Spa, Autograph Collection
The Pelican Key Largo Cottages

The Pelican Key Largo Cottages

2 out of 5
99340 Overseas Highway, Key Largo, FL
  • 9 min drive from John Pennekamp Coral Reef State Park
The Pelican Key Largo Cottages offers a luxury stay. Popular amenities include a private beach, a marina, and a terrace.
8.6/10 Excellent! (1,011 reviews)
"Love the access to the water. Love the amount of rooms to choose from. Employees were helpful and friendly."

Reviewed on Sep 15, 2025

The Pelican Key Largo Cottages
Bayside Inn Key Largo

Bayside Inn Key Largo

3 out of 5
99490 Overseas Hwy, Key Largo, FL
  • 9 min drive from John Pennekamp Coral Reef State Park
Spoil yourself with a luxury vacation in Key Largo. Popular amenities include a private beach, an outdoor pool, and a restaurant.
8.4/10 Very Good! (1,569 reviews)
Nice place to stay in Key Largo
"Nice motel with a variety of amenities - 2 water bottles in room daily, bikes & paddle boards on site to use, access to pool & bay with lots of outdoor seating. Unfortunately only 5 rooms have a view of bay. Starbucks Keurig in lobby makes great chai latte! Appreciated recommendations for dining ..."

Reviewed on Sep 18, 2025

Bayside Inn Key Largo
See all 1,820 properties in Key Largo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.