Upstate South Carolina Pet-friendly Vacations 2026

Photo by RVLuckyorWhat

Plan, book, travel with confidence
Better together
Save up to ₩1,660,000 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place

Top Pet-friendly Upstate South Carolina Hotels

Aloft by Marriott Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Four-legged friends will enjoy free stays and pet-approved amenities, like food and water bowls, at this city-center hotel. If you need a walk during your visit, ...

9.2/10 Wonderful! (1,009 reviews)

"Great location"

Reviewed on Aug 20, 2026

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Butler Springs Park.

7.4/10 Good! (1,137 reviews)

"Shaft was friendly and the room was very clean"

Reviewed on Aug 21, 2026

Clarion Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.6/10 Good! (31 reviews)

"We needed an inexpensive place to sleep before an early flight out of GSP, and this hotel met our needs, and only 7 minutes to the airport. The room appeared recently renovated and was clean. We didn’t use any of the hotel’s amenities. The surrounding area isn’t the nicest, but we had no issues, ..."

Reviewed on Aug 20, 2026

See all 3,052 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.