Eastern South Dakota Pet-friendly Vacations

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Top Pet-friendly Eastern South Dakota Hotels

La Quinta Inn & Suites by Wyndham Sioux Falls

La Quinta Inn & Suites by Wyndham Sioux Falls

3 out of 5
4521 W. 41st Street, Sioux Falls, SD
  • 9 min drive from Denny Sanford Premier Center
Dogs and cats may join you (for a fee) during your stay at this pet-friendly hotel. Take the opportunity to stretch your legs on the nearby hiking or biking ...
9/10 Wonderful! (1,456 reviews)
"This was a last minute booking due to a hospital stay and everything was great. Quiet hotel, convenient to the interstate, clean rooms, and comfy beds. The nicest LaQuinta I've stayed at!"

Reviewed on Aug 21, 2025

La Quinta Inn & Suites by Wyndham Sioux Falls
Econo Lodge Sioux Falls Empire Mall

Econo Lodge Sioux Falls Empire Mall

2 out of 5
3500 Gateway Boulevard, Sioux Falls, SD
  • 9 min drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs and cats (fees apply).
Economy hotel, no thrills, but it's nice
"Staff was really nice. Rooms are spacious. Good value and convenient to many stores/restaurants, etc. Rooms for clean."

Reviewed on Oct 18, 2022

Econo Lodge Sioux Falls Empire Mall
Kelly Inn & Suites Mitchell South Dakota

Kelly Inn & Suites Mitchell South Dakota

2.5 out of 5
1010 Cabela Drive, Mitchell, SD
  • 3 hours drive from Denny Sanford Premier Center
This pet-friendly hotel welcomes dogs for free.
8/10 Very Good! (1,028 reviews)
"Rooms were clean and comfortable. Staff was friendly and helpful. The fitness center could be cleaned and better arranged, and the tv didn’t work. Breakfast was decent."

Reviewed on Aug 19, 2025

Kelly Inn & Suites Mitchell South Dakota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.