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Top Pet-friendly Southern Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

4353 Canal Pl SE Rochester MN

11 min drive from Mayo Clinic

Make it a pet-friendly trip and bring along your four-legged friend. Dogs are welcome (fees apply) at this suburban hotel.

7.2/10 Good! (1,024 reviews)

Clean and quiet. Great breakfast

Reviewed on Nov 26, 2025

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Dogs are welcome to join you (fees apply) for a pet-friendly getaway at this family-friendly, city-center motel.

7.8/10 Good! (1,012 reviews)

Staff was super helpful, great breakfast, shirt drive to Mayo

Reviewed on Nov 24, 2025

Spark by Hilton Rochester South

4165 Maine Ave SE Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (294 reviews)

The pool was nice. The people in the room next to us were playing loud music, so had to call the front desk to get them to make those people turn down the music. The issue was handled successfully.

Reviewed on Dec 1, 2025

See all 1,190 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.