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Top Romantic Southwest Houston Hotels

Hotel Granduca Houston

1080 Uptown Park Blvd Houston TX

9 min drive from MD Anderson Cancer Center

In-room massages, al fresco dining, and a garden await couples looking for a romantic getaway at this upscale hotel. The property also offers a hot tub, happy ...

9.2/10 Wonderful! (1,000 reviews)

Couples like: al fresco dining, hot tub, couples dining, champagne service

Travelers say...

On Expedia shows a certain caliber of reviews and stars for the quality of the hotel and the service just did not match what was promised. The service in general was very slow. Between the valet service and request requesting things from the front desk I always had to call twice. Additionally, I ...

Reviewed on Mar 1, 2026

Omni Houston Hotel

4 Riverway Houston TX

9 min drive from MD Anderson Cancer Center

Rekindle the romance with your special someone. Consider booking a getaway at this hotel where you're sure to love the hot tub and spa. Other amenities to enjoy ...

9.2/10 Wonderful! (1,005 reviews)

Couples like: full-service spa, couples spa treatments, bar, hot tub

Travelers say...

Our stay at the Omni is always wonderful. I will say, though that our room did not have a refrigerator and was a little outdated, but the overall facility is wonderful.

Reviewed on Mar 30, 2026

Houston Grand Hotel - River Oaks

1919 Briar Oaks Ln Houston TX

7 min drive from MD Anderson Cancer Center

In-room massages, a garden, and onsite dining await couples looking for a romantic getaway at this boutique hotel. The property also offers Egyptian cotton sheets, ...

9.2/10 Wonderful! (421 reviews)

We absolutely loved our stay and we will be staying there again.

Reviewed on Mar 30, 2026

See all 1,266 properties in Southwest Houston

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.