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Top Adventure Southern Minnesota Hotels

Kahler Grand Hotel

20 2nd Ave Sw Rochester MN

2 min walk from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free WiFi, 2 restaurants, and breakfast (surcharge). Our guests praise the helpful staff and ...

8.2/10 Very Good! (1,883 reviews)

The room was clean and comfortable. The location was outstanding. Only compliant was that they missed servicing my room one day.

Reviewed on Feb 7, 2026

Country Inn & Suites by Radisson, Rochester, MN

4323 Highway 52 North, West Frontage Rd Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (1,001 reviews)

Room is clean. Staff was courteous.

Reviewed on Jan 23, 2026

AmericInn by Wyndham Mankato Event Center

240 Stadium Road Mankato MN

4 hours drive from Mayo Clinic

Book a stay at this business-friendly hotel in Mankato. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...

9/10 Wonderful! (1,000 reviews)

Staff was very nice and polite Rooms are spacious and clean

Reviewed on Jan 28, 2026

See all 1,200 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.