Big Pine Key Adventure Vacations
Book a Adventure Hotel + Flight or Car together to unlock savings
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Adventure Big Pine Key Hotels
Deer Run Bed & Breakfast
1997 Long Beach Road, Big Pine Key, FL
Book a stay at this beach B&B in Big Pine Key. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Coupon Bight Aquatic Preserve and Cook ...
"Loved it. Beautiful property."
Reviewed on Aug 21, 2017
Ed & Ellen's Lodging Big Pine Key
1547 Narcissus Ave, Big Pine Key, FL
Stay at this 3-star apartment in Big Pine Key. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Blue Hole and Big Pine Key Flea Market ...
Nice place but not luxurious.
"It was wonderful for privacy, quietness, and relaxing. We saw no staff and that was ok with us. Dated interior but comfortable."
Reviewed on Apr 22, 2019
Old Wooden Bridge Resort and Marina
1791 Bogie Drive, Big Pine Key, FL
Stay at this cottage in Big Pine Key. Enjoy free WiFi, free parking, and a marina. Our guests praise the helpful staff in our reviews. Popular attractions Blue ...
8.4/10 Very Good! (243 reviews)
"The place was clean, really comfortable, had a lot of space, was charming. Nothing to complain about it. We had an issue and the office resolved right away. Loved this place and would recommend for sure!"
Reviewed on Jun 25, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Vacation Ideas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.