Panama Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
Photo by PhotoJoy
- Plan, book, travel with confidence
Better together
Save up to ₩234,741 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Luxury Panama Hotels
JW Marriott Panama
Calle Punta Colon, Punta Pacifica, Panama City, Panama
The price is ₩308,831 per night from Oct 11 to Oct 12
₩308,831
₩339,714 total
Oct 11 - Oct 12
includes taxes & fees
Be treated to luxurious accommodations at JW Marriott Panama, where you can enjoy amenities like massage services, 24-hour room service, and more. The 4 outdoor ...
8.8/10 Excellent! (1,014 reviews)
"Property of HUGE"
Reviewed on Sep 27, 2025
Bristol Panama, a Registry Collection Hotel
Avenida Aquilino de La Guardia, Bella Vista, Panama City, Panama
The price is ₩250,403 per night from Nov 1 to Nov 2
₩250,403
₩275,443 total
Nov 1 - Nov 2
includes taxes & fees
Treat yourself to some sumptuous lodging at Bristol Panama, a Registry Collection Hotel, where you'll find deep soaking bathtubs and pillowtop beds. Notable ...
9.2/10 Wonderful! (1,013 reviews)
"Excelent atention to detail, recomended stay."
Reviewed on Sep 20, 2025
Waldorf Astoria Panama
47th St. & Uruguay Street, Panama City, Panama
The price is ₩314,372 per night from Oct 25 to Oct 26
₩314,372
₩345,809 total
Oct 25 - Oct 26
includes taxes & fees
Pamper yourself with a luxury stay at Waldorf Astoria Panama, where you can enjoy amenities like Champagne service, 24-hour room service, and more. The 2 bars, ...
8.8/10 Excellent! (1,008 reviews)
"Oliver was a pleasure and very informative on the surrounding areas, include very pleasant attitude with a smile on his face daily !! Thank you Oliver !!"
Reviewed on Sep 29, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
More Vacation Ideas
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
